TP53 Regulates Metabolic Genes

No Pathway Network information available for TP53 Regulates Metabolic Genes

Pathways in the TP53 Regulates Metabolic Genes SuperPath

#	Name	Source	Genes
1	TP53 Regulates Metabolic Genes	Reactome	AGO1 AGO2 AGO3 AGO4 AKT1 AKT2 AKT3 COX4I1 COX4I2 COX5A COX5B COX6A1 COX6A2 COX6B1 COX6B2 COX6C COX7A1 COX7A2 COX7A2L COX7B COX7C COX8A COX8C COXFA4 DDIT4 G6PD GLS GLS2 GPI GPX2 GSR HIGD1C LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 MLST8 MOV10 MT-CO1 MT-CO2 MT-CO3 MTOR PRDX1 PRDX2 PRDX5 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 PTEN RHEB RPTOR RRAGA RRAGB RRAGC RRAGD RRM2B SCO2 SESN1 SESN2 SESN3 SFN SLC38A9 TIGAR TNRC6A TNRC6B TNRC6C TP53 TSC1 TSC2 TXN TXNRD1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 82) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	1
2	RRAGB	Ras Related GTP Binding B	Protein Coding	1
3	LAMTOR5	Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 5	Protein Coding	1
4	RRAGA	Ras Related GTP Binding A	Protein Coding	1
5	YWHAQ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Theta	Protein Coding	1
6	COX6B2	Cytochrome C Oxidase Subunit 6B2	Protein Coding	1
7	COX4I1	Cytochrome C Oxidase Subunit 4I1	Protein Coding	1
8	COX5B	Cytochrome C Oxidase Subunit 5B	Protein Coding	1
9	COX6A1	Cytochrome C Oxidase Subunit 6A1	Protein Coding	1
10	COX6A2	Cytochrome C Oxidase Subunit 6A2	Protein Coding	1
11	COX6B1	Cytochrome C Oxidase Subunit 6B1	Protein Coding	1
12	COX6C	Cytochrome C Oxidase Subunit 6C	Protein Coding	1
13	COX7A1	Cytochrome C Oxidase Subunit 7A1	Protein Coding	1
14	COX7A2	Cytochrome C Oxidase Subunit 7A2	Protein Coding	1
15	COX7B	Cytochrome C Oxidase Subunit 7B	Protein Coding	1
16	COX7C	Cytochrome C Oxidase Subunit 7C	Protein Coding	1
17	COX8A	Cytochrome C Oxidase Subunit 8A	Protein Coding	1
18	SESN3	Sestrin 3	Protein Coding	1
19	SLC38A9	Solute Carrier Family 38 Member 9	Protein Coding	1
20	AGO3	Argonaute RISC Catalytic Component 3	Protein Coding	1
21	AGO4	Argonaute RISC Component 4	Protein Coding	1
22	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
23	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	1
24	TNRC6B	Trinucleotide Repeat Containing Adaptor 6B	Protein Coding	1
25	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	1
26	G6PD	Glucose-6-Phosphate Dehydrogenase	Protein Coding	1
27	PRDX5	Peroxiredoxin 5	Protein Coding	1
28	AGO1	Argonaute RISC Component 1	Protein Coding	1
29	AGO2	Argonaute RISC Catalytic Component 2	Protein Coding	1
30	GLS2	Glutaminase 2	Protein Coding	1
31	SESN1	Sestrin 1	Protein Coding	1
32	TNRC6A	Trinucleotide Repeat Containing Adaptor 6A	Protein Coding	1
33	GLS	Glutaminase	Protein Coding	1
34	SFN	Stratifin	Protein Coding	1
35	GPI	Glucose-6-Phosphate Isomerase	Protein Coding	1
36	GPX2	Glutathione Peroxidase 2	Protein Coding	1
37	LAMTOR2	Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 2	Protein Coding	1
38	GSR	Glutathione-Disulfide Reductase	Protein Coding	1
39	COX8C	Cytochrome C Oxidase Subunit 8C	Protein Coding	1
40	LAMTOR4	Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 4	Protein Coding	1
41	MOV10	Mov10 RNA Helicase	Protein Coding	1
42	MT-CO1	Mitochondrially Encoded Cytochrome C Oxidase I	Protein Coding	1
43	MT-CO2	Mitochondrially Encoded Cytochrome C Oxidase II	Protein Coding	1
44	MT-CO3	Mitochondrially Encoded Cytochrome C Oxidase III	Protein Coding	1
45	COXFA4	Cytochrome C Oxidase Associated Subunit FA4	Protein Coding	1
46	RRM2B	Ribonucleotide Reductase Regulatory TP53 Inducible Subunit M2B	Protein Coding	1
47	PRDX1	Peroxiredoxin 1	Protein Coding	1
48	PRKAG2	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 2	Protein Coding	1
49	PRKAG3	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 3	Protein Coding	1
50	DDIT4	DNA Damage Inducible Transcript 4	Protein Coding	1
51	LAMTOR1	Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 1	Protein Coding	1
52	PRKAA1	Protein Kinase AMP-Activated Catalytic Subunit Alpha 1	Protein Coding	1
53	PRKAA2	Protein Kinase AMP-Activated Catalytic Subunit Alpha 2	Protein Coding	1
54	PRKAB1	Protein Kinase AMP-Activated Non-Catalytic Subunit Beta 1	Protein Coding	1
55	PRKAB2	Protein Kinase AMP-Activated Non-Catalytic Subunit Beta 2	Protein Coding	1
56	PRKAG1	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 1	Protein Coding	1
57	TIGAR	TP53 Induced Glycolysis Regulatory Phosphatase	Protein Coding	1
58	PTEN	Phosphatase And Tensin Homolog	Protein Coding	1
59	RPTOR	Regulatory Associated Protein Of MTOR Complex 1	Protein Coding	1
60	TNRC6C	Trinucleotide Repeat Containing Adaptor 6C	Protein Coding	1
61	RRAGD	Ras Related GTP Binding D	Protein Coding	1
62	RHEB	Ras Homolog, MTORC1 Binding	Protein Coding	1
63	HIGD1C	HIG1 Hypoxia Inducible Domain Family Member 1C	Protein Coding	1
64	RRAGC	Ras Related GTP Binding C	Protein Coding	1
65	MLST8	MTOR Associated Protein MLST8	Protein Coding	1
66	PRDX2	Peroxiredoxin 2	Protein Coding	1
67	TP53	Tumor Protein P53	Protein Coding	1
68	TSC1	TSC Complex Subunit 1	Protein Coding	1
69	TSC2	TSC Complex Subunit 2	Protein Coding	1
70	TXN	Thioredoxin	Protein Coding	1
71	TXNRD1	Thioredoxin Reductase 1	Protein Coding	1
72	YWHAB	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Beta	Protein Coding	1
73	YWHAE	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon	Protein Coding	1
74	YWHAG	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamma	Protein Coding	1
75	YWHAH	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Eta	Protein Coding	1
76	YWHAZ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta	Protein Coding	1
77	SESN2	Sestrin 2	Protein Coding	1
78	COX4I2	Cytochrome C Oxidase Subunit 4I2	Protein Coding	1
79	LAMTOR3	Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 3	Protein Coding	1
80	COX7A2L	Cytochrome C Oxidase Subunit 7A2 Like	Protein Coding	1
81	COX5A	Cytochrome C Oxidase Subunit 5A	Protein Coding	1
82	SCO2	Synthesis Of Cytochrome C Oxidase 2	Protein Coding	1

Disorders associated with TP53 Regulates Metabolic Genes SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Cox deficiency, benign infantile mitochondrial myopathy	Enrichment	COX4I1, COX5A, COX6A2, COX6B1, COX8A, MT-CO1, MT-CO2, MT-CO3	10.76
2	Focal cortical dysplasia, type ii	Enrichment	MTOR, RHEB, TSC1, TSC2	8.90
3	Isolated focal cortical dysplasia type ii	Enrichment	MTOR, RHEB, TSC1, TSC2	8.90
4	Mitochondrial complex iv deficiency, nuclear type 1	Enrichment	COX4I1, COX6B1, COX8A, MT-CO1, MT-CO2, MT-CO3	8.55
5	Hemimegalencephaly	Enrichment	AKT3, MTOR, PTEN, RHEB	8.21
6	Mitochondrial myopathy, infantile, transient	Enrichment	MT-CO1, MT-CO2, MT-CO3	4.76
7	Adult hepatocellular carcinoma	Enrichment	TP53, TSC1, TSC2	4.76
8	Familial colorectal cancer	Enrichment	MT-CO1, MT-CO2, TP53	4.61
9	Mitochondrial myopathy with reversible cytochrome c oxidase deficiency	Enrichment	MT-CO1, MT-CO2, MT-CO3	4.61
10	Lymphangioleiomyomatosis	Enrichment	TSC1, TSC2	4.44
11	Tuberous sclerosis 1	Enrichment	TSC1, TSC2	3.97
12	Hamartoma	Enrichment	TSC1, TSC2	3.97
13	Tuberous sclerosis	Enrichment	TSC1, TSC2	3.67
14	Hereditary recurrent myoglobinuria	Enrichment	MT-CO1, MT-CO3	3.67
15	Acute megakaryocytic leukemia	Enrichment	PTEN, TP53	3.45
16	Tetralogy of fallot	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.30
17	Mitochondrial complex v deficiency, mitochondrial type 1	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.30
18	Neuropathy, ataxia, and retinitis pigmentosa	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.30
19	Striatonigral degeneration, infantile, mitochondrial	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.30
20	Camptodactyly of fingers	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.30
21	Breast adenocarcinoma	Enrichment	AKT1, TP53	3.27
22	Bladder cancer	Enrichment	PTEN, TP53, TSC1	3.16
23	Squamous cell carcinoma, head and neck	Enrichment	PTEN, TP53	3.13
24	Cowden syndrome	Enrichment	AKT1, PTEN	2.90
25	Mitochondrial neurogastrointestinal encephalomyopathy	Enrichment	RRM2B, SCO2	2.90
26	Leber hereditary optic neuropathy, modifier of	Enrichment	MT-CO1, MT-CO2, MT-CO3	2.85
27	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	Enrichment	MT-CO1, MT-CO2, MT-CO3	2.81
28	Mitochondrial disease	Enrichment	MT-CO1, MT-CO2, MT-CO3, RRM2B	2.72
29	Meningioma	Enrichment	AKT1, PTEN	2.64
30	Hereditary breast carcinoma	Enrichment	AKT1, PTEN, TP53	2.63
31	Ovarian cancer	Enrichment	AKT1, PTEN, TP53, TSC2	2.49
32	Hypertelorism	Enrichment	MT-CO1, MT-CO2, MT-CO3	2.42
33	Rhabdomyosarcoma	Enrichment	PTEN, TP53	2.39
34	Diffuse large b-cell lymphoma	Enrichment	PTEN, TP53	2.24
35	Proteus syndrome	Enrichment	AKT1	2.22
36	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	2.22
37	Linear skin defects with multiple congenital anomalies 2	Enrichment	COX7B	2.22
38	Vacterl association with hydrocephalus	Enrichment	PTEN	2.22
39	Immunodeficiency due to defect in mapbp-interacting protein	Enrichment	LAMTOR2	2.22
40	Myoglobinuria, recurrent	Enrichment	MT-CO1	2.22
41	Global developmental delay with speech and behavioral abnormalities	Enrichment	TNRC6B	2.22
42	Anemia, congenital, nonspherocytic hemolytic, 10	Enrichment	GSR	2.22
43	Mitochondrial complex iv deficiency, nuclear type 18	Enrichment	COX6A2	2.22
44	Casgid syndrome	Enrichment	GLS	2.22
45	Bone marrow failure syndrome 5	Enrichment	TP53	2.22
46	Papilloma of choroid plexus	Enrichment	TP53	2.22
47	Basal cell carcinoma 7	Enrichment	TP53	2.22
48	Anaplastic thyroid carcinoma	Enrichment	TP53	2.22
49	Cardiomyopathy, familial hypertrophic, 6	Enrichment	PRKAG2	2.22
50	Mitochondrial dna depletion syndrome 8b	Enrichment	RRM2B	2.22
51	Papillary tumor of the pineal region	Enrichment	PTEN	2.22
52	Glycogen storage disease of heart, lethal congenital	Enrichment	PRKAG2	2.22
53	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	2.22
54	Developmental and epileptic encephalopathy 71	Enrichment	GLS	2.22
55	Cowden syndrome 6	Enrichment	AKT1	2.22
56	Anemia, congenital, nonspherocytic hemolytic, 4	Enrichment	GPI	2.22
57	Exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial hyperostosis	Enrichment	COX4I2	2.22
58	Glioma susceptibility 2	Enrichment	PTEN	2.22
59	Ductal carcinoma in situ	Enrichment	TP53	2.22
60	Developmental and epileptic encephalopathy 56	Enrichment	YWHAG	2.22
61	Epilepsy, familial adult myoclonic, 6	Enrichment	TNRC6A	2.22
62	Skeletal muscle glycogen content and metabolism quantitative trait locus	Enrichment	PRKAG3	2.22
63	Mitochondrial complex iv deficiency, nuclear type 7	Enrichment	COX6B1	2.22
64	Mitochondrial complex iv deficiency, nuclear type 20	Enrichment	COX5A	2.22
65	Mitochondrial complex iv deficiency, nuclear type 16	Enrichment	COX4I1	2.22
66	Mitochondrial complex iv deficiency, nuclear type 21	Enrichment	COXFA4	2.22
67	Mitochondrial complex iv deficiency, nuclear type 15	Enrichment	COX8A	2.22
68	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	2.22
69	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	2.22
70	Charcot-marie-tooth disease, recessive intermediate d	Enrichment	COX6A1	2.22
71	Capillary hemangioma	Enrichment	AKT3	2.22
72	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	2.22
73	Autosomal recessive axonal charcot-marie-tooth disease due to copper metabolism defect	Enrichment	SCO2	2.22
74	Pancreatic insufficiency-anemia-hyperostosis syndrome	Enrichment	COX4I2	2.22
75	Spastic ataxia-dysarthria due to glutaminase deficiency	Enrichment	GLS	2.22
76	Choroid plexus cancer	Enrichment	TP53	2.22
77	Congenital nonspherocytic hemolytic anemia	Enrichment	G6PD	2.22
78	Autosomal dominant spastic ataxia	Enrichment	MT-CO3	2.22
79	Pleomorphic xanthoastrocytoma	Enrichment	TP53	2.22
80	Primary immunodeficiency syndrome due to p14 deficiency	Enrichment	LAMTOR2	2.22
81	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	2.22
82	Distal 17p13.3 microdeletion syndrome	Enrichment	YWHAE	2.22
83	Rrm2b mitochondrial dna maintenance defects	Enrichment	RRM2B	2.22
84	Tubular renal disease-cardiomyopathy syndrome	Enrichment	RRAGD	2.22
85	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	2.22
86	Inherited cancer-predisposing syndrome	Enrichment	PTEN, TP53, TSC1, TSC2	2.08
87	Leigh syndrome, nuclear	Enrichment	MT-CO1, MT-CO2, MT-CO3	2.08
88	Breast cancer	Enrichment	AKT1, PTEN, TP53	1.98
89	Leigh disease	Enrichment	MT-CO1, MT-CO2, MT-CO3	1.96
90	Fanconi renotubular syndrome 1	Enrichment	RRM2B	1.92
91	Adrenocortical carcinoma, hereditary	Enrichment	TP53	1.92
92	Cervical cancer	Enrichment	TP53	1.92
93	Rod-cone dystrophy, sensorineural deafness, and fanconi-type renal dysfunction	Enrichment	RRM2B	1.92
94	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 5	Enrichment	RRM2B	1.92
95	Premature ovarian failure 3	Enrichment	AGO2	1.92
96	Mitochondrial dna depletion syndrome 8a	Enrichment	RRM2B	1.92
97	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal recessive 2	Enrichment	RRM2B	1.92
98	Lymphoma, hodgkin, classic	Enrichment	TP53	1.92
99	Global developmental delay, progressive ataxia, and elevated glutamine	Enrichment	GLS	1.92
100	Hypomagnesemia 7, renal, with or without dilated cardiomyopathy	Enrichment	RRAGD	1.92
101	Neurodevelopmental disorder with language delay and behavioral abnormalities, with or without seizures	Enrichment	AGO1	1.92
102	Cebalid syndrome	Enrichment	MTOR	1.92
103	Myopia 6	Enrichment	SCO2	1.92
104	Senior-loken syndrome 7	Enrichment	AKT3	1.92
105	Congenital fibrosarcoma	Enrichment	TP53	1.92
106	Li-fraumeni syndrome 1	Enrichment	TP53	1.92
107	Sarcoma	Enrichment	TP53	1.92
108	Congenital hemolytic anemia	Enrichment	G6PD	1.92
109	Cervix carcinoma	Enrichment	TP53	1.92
110	Hodgkin's lymphoma	Enrichment	TP53	1.92
111	Bardet-biedl syndrome 16	Enrichment	AKT3	1.92
112	Smith-kingsmore syndrome	Enrichment	MTOR	1.92
113	Glucosephosphate dehydrogenase deficiency	Enrichment	G6PD	1.92
114	Long-olsen-distelmaier syndrome	Enrichment	RRAGC	1.92
115	Vacterl with hydrocephalus	Enrichment	PTEN	1.92
116	Juvenile polyposis of infancy	Enrichment	PTEN	1.92
117	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	1.92
118	Prostate cancer	Enrichment	PTEN, TP53	1.88
119	Colorectal cancer	Enrichment	AKT1, MT-CO1, TP53	1.80
120	Keratoderma, palmoplantar, with deafness	Enrichment	MT-CO1	1.74
121	Polycystic kidney disease, infantile severe, with tuberous sclerosis	Enrichment	TSC2	1.74
122	Linear skin defects with multiple congenital anomalies 1	Enrichment	COX7B	1.74
123	Mitochondrial complex iv deficiency, nuclear type 2	Enrichment	SCO2	1.74
124	Osteogenic sarcoma	Enrichment	TP53	1.74
125	Nasopharyngeal carcinoma	Enrichment	TP53	1.74
126	Tuberous sclerosis 2	Enrichment	TSC2	1.74
127	Miller-dieker lissencephaly syndrome	Enrichment	YWHAE	1.74
128	Chromosome 17p13.3, centromeric, duplication syndrome	Enrichment	YWHAE	1.74
129	Atypical teratoid rhabdoid tumor	Enrichment	TP53	1.74
130	Anaplastic astrocytoma	Enrichment	TP53	1.74
131	Xanthinuria, type ii	Enrichment	TSC2	1.74
132	Squamous cell carcinoma	Enrichment	TP53	1.74
133	Adenocarcinoma	Enrichment	TP53	1.74
134	Laryngeal squamous cell carcinoma	Enrichment	PTEN	1.74
135	Bone osteosarcoma	Enrichment	TP53	1.74
136	Lessel-kreienkamp syndrome	Enrichment	AGO2	1.74
137	Idiopathic camptocormia	Enrichment	RRM2B	1.74
138	Myelodysplastic syndrome with ring sideroblasts	Enrichment	MT-CO1	1.74
139	Leber plus disease	Enrichment	MT-CO1, MT-CO2, MT-CO3	1.70
140	Small cell cancer of the lung	Enrichment	TP53	1.62
141	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	1.62
142	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3	1.62
143	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3	1.62
144	Lung sarcomatoid carcinoma	Enrichment	TP53	1.62
145	Embryonal rhabdomyosarcoma	Enrichment	TP53	1.62
146	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	YWHAZ	1.62
147	Glioma	Enrichment	PTEN	1.62
148	Gastric cancer	Enrichment	PTEN, TP53	1.56
149	Autism spectrum disorder	Enrichment	PTEN, TNRC6B, TSC2	1.55
150	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	G6PD	1.52
151	Kearns-sayre syndrome	Enrichment	RRM2B	1.52
152	Rhabdomyosarcoma 2	Enrichment	TP53	1.52
153	Macrocephaly/autism syndrome	Enrichment	PTEN	1.52
154	Cox deficiency, infantile mitochondrial myopathy	Enrichment	SCO2	1.52
155	Lymphoma	Enrichment	TP53	1.52
156	Hemangioma	Enrichment	PTEN	1.52
157	Rare isolated myopia	Enrichment	SCO2	1.52
158	Endometrial stromal sarcoma	Enrichment	YWHAE	1.52
159	Li-fraumeni syndrome	Enrichment	TP53	1.45
160	Cowden syndrome 1	Enrichment	PTEN	1.45
161	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 1	Enrichment	RRM2B	1.45
162	Deafness, nonsyndromic sensorineural, mitochondrial	Enrichment	MT-CO1	1.45
163	Mitochondrial dna depletion syndrome 1	Enrichment	SCO2	1.45
164	Keratoconus	Enrichment	TSC1	1.45
165	Adrenocortical carcinoma	Enrichment	TP53	1.45
166	Hereditary spherocytosis	Enrichment	GPI	1.45
167	Kidney clear cell sarcoma	Enrichment	YWHAE	1.45
168	Complex neurodevelopmental disorder	Enrichment	AGO1, AGO2, TNRC6B	1.41
169	Retinitis pigmentosa	Enrichment	MT-CO1, MT-CO2, MT-CO3, RRM2B	1.40
170	Esophageal cancer	Enrichment	TP53	1.38
171	Polycystic kidney disease 1 with or without polycystic liver disease	Enrichment	TSC2	1.38
172	Thyroid cancer, nonmedullary, 2	Enrichment	PTEN	1.38
173	Renal cell carcinoma, papillary, 1	Enrichment	MTOR	1.38
174	Polycystic kidney disease 1	Enrichment	TSC2	1.38
175	Essential thrombocythemia	Enrichment	TP53	1.38
176	Gallbladder cancer	Enrichment	TP53	1.38
177	Megacolon	Enrichment	AKT3	1.38
178	Follicular thyroid carcinoma	Enrichment	PTEN	1.38
179	Hemolytic anemia	Enrichment	GPI	1.38
180	Overgrowth syndrome	Enrichment	MTOR	1.38
181	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	TP53	1.38
182	Hereditary breast ovarian cancer syndrome	Enrichment	PTEN, TP53	1.36
183	Glioma susceptibility 1	Enrichment	TP53	1.32
184	Methylmalonic aciduria and homocystinuria, cblc type	Enrichment	PRDX1	1.32
185	Lymphoma, non-hodgkin, familial	Enrichment	TP53	1.32
186	Mitochondrial dna depletion syndrome 4b	Enrichment	SCO2	1.32
187	Coronary heart disease 5	Enrichment	G6PD	1.27
188	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	TNRC6B	1.27
189	Primary hyperaldosteronism	Enrichment	TP53	1.27
190	Leukemia, chronic lymphocytic	Enrichment	TP53	1.23
191	Polymicrogyria	Enrichment	AKT3	1.23
192	Melanoma	Enrichment	PTEN	1.23
193	Rare mitochondrial non-syndromic sensorineural deafness	Enrichment	MT-CO1	1.23
194	Meningioma, familial	Enrichment	PTEN	1.19
195	Myelodysplastic syndrome	Enrichment	TP53	1.19
196	Uterine corpus cancer	Enrichment	PTEN	1.19
197	Specific learning disability	Enrichment	YWHAG	1.19
198	Lip and oral cavity carcinoma	Enrichment	TP53	1.15
199	Lung cancer susceptibility 3	Enrichment	TP53	1.09
200	Renal cell carcinoma, nonpapillary	Enrichment	MTOR	1.06
201	Autosomal dominant polycystic kidney disease	Enrichment	TSC2	1.06
202	Kidney disease	Enrichment	TSC1	1.06
203	Rare genetic intellectual disability	Enrichment	MTOR	1.06
204	Wolff-parkinson-white syndrome	Enrichment	PRKAG2	1.03
205	Gliosarcoma	Enrichment	TP53	1.03
206	Giant cell glioblastoma	Enrichment	TP53	1.01
207	Esophageal atresia/tracheoesophageal fistula	Enrichment	GLS	0.96
208	Endometrial cancer	Enrichment	PTEN	0.92
209	Hepatoblastoma	Enrichment	TP53	0.92
210	Hepatocellular carcinoma	Enrichment	TP53	0.90
211	Diamond-blackfan anemia 1	Enrichment	TP53	0.89
212	Malaria	Enrichment	G6PD	0.89
213	Congenital nervous system abnormality	Enrichment	PTEN, TSC2	0.87
214	Nervous system disease	Enrichment	PTEN, TSC2	0.87
215	Pancreatic cancer	Enrichment	TP53	0.85
216	Peripheral nervous system disease	Enrichment	COX6A1	0.75
217	Neuropathy	Enrichment	COX6A1	0.75
218	Familial hypertrophic cardiomyopathy	Enrichment	PRKAG2	0.74
219	Diamond-blackfan anemia	Enrichment	TP53	0.71
220	Leukemia, acute myeloid	Enrichment	TP53	0.67
221	Epilepsy	Enrichment	MT-CO3	0.67
222	Type 2 diabetes mellitus	Enrichment	AKT2	0.65
223	Hypertrophic cardiomyopathy	Enrichment	PRKAG2	0.64
224	West syndrome	Enrichment	TSC2	0.63
225	Sensorineural hearing loss	Enrichment	RRM2B	0.60
226	Autosomal dominant non-syndromic intellectual disability	Enrichment	YWHAZ	0.58
227	Myeloma, multiple	Enrichment	TP53	0.54
228	Undetermined early-onset epileptic encephalopathy	Enrichment	YWHAG	0.54
229	Dilated cardiomyopathy	Enrichment	SCO2	0.41
230	Microcephaly	Enrichment	YWHAG	0.28

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

TP53 Regulates Metabolic Genes

Pathway Network for TP53 Regulates Metabolic Genes

Member Pathways for TP53 Regulates Metabolic Genes

Pathways in the TP53 Regulates Metabolic Genes SuperPath

Associated Genes for TP53 Regulates Metabolic Genes

Associated Disorders for TP53 Regulates Metabolic Genes

Disorders associated with TP53 Regulates Metabolic Genes SuperPath

STRING Interaction Network for TP53 Regulates Metabolic Genes

Sources for TP53 Regulates Metabolic Genes