Transcription Androgen Receptor nuclear signaling

No Pathway Network information available for Transcription Androgen Receptor nuclear signaling

Pathways in the Transcription Androgen Receptor nuclear signaling SuperPath

#	Name	Source	Genes
1	Transcription Androgen Receptor nuclear signaling	GeneGo (Thomson Reuters)	AKT1 AR CCND1 CDKN1A CTNNB1 DVL1 DVL2 DVL3 EGF EGFR EP300 EZR FZD1 FZD10 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GRB2 GSK3B HRAS IGF1 IGF1R IL6 IL6R IL6ST KLK3 MAP2K1 MAPK1 MMP2 NCOA1 NCOA2 NCOR1 PAK6 PRKACA PRKACB PRKACG PTK2B RAD9A RAD9B RAF1 SCAP SHC1 SMAD3 SOS1 SOS2 SRD5A1 SRD5A2 STAT3 TGFB1 TGFB1I1 TGFBR1 TGFBR2 WNT1 WNT10A WNT10B WNT11 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B (see all 76) (see less)
2	Translation Non-genomic (rapid) action of Androgen Receptor	GeneGo (Thomson Reuters)	AKT1 AKT2 AKT3 AR CAV1 CTNNB1 DVL1 DVL2 DVL3 EGF EGFR EIF4EBP1 ERBB2 FOXO3 FZD1 FZD10 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GRB2 GSK3B HBEGF HRAS IRS1 MAP2K1 MAPK1 MDM2 MTOR NFKB1 NFKB2 NRG1 PIK3CA PIK3R1 PTEN RAF1 REL RELA RELB RPS6KB1 SHC1 SOS1 SOS2 SRC SRD5A1 SRD5A2 TSC2 WNT1 WNT10A WNT10B WNT11 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B (see all 70) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	2
2	AR	Androgen Receptor	Protein Coding	2
3	CTNNB1	Catenin Beta 1	Protein Coding	2
4	DVL1	Dishevelled Segment Polarity Protein 1	Protein Coding	2
5	DVL2	Dishevelled Segment Polarity Protein 2	Protein Coding	2
6	DVL3	Dishevelled Segment Polarity Protein 3	Protein Coding	2
7	EGF	Epidermal Growth Factor	Protein Coding	2
8	EGFR	Epidermal Growth Factor Receptor	Protein Coding	2
9	FZD2	Frizzled Class Receptor 2	Protein Coding	2
10	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	2
11	GSK3B	Glycogen Synthase Kinase 3 Beta	Protein Coding	2
12	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	2
13	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	2
14	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	2
15	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	2
16	SHC1	SHC Adaptor Protein 1	Protein Coding	2
17	SOS1	SOS Ras/Rac Guanine Nucleotide Exchange Factor 1	Protein Coding	2
18	SOS2	SOS Ras/Rho Guanine Nucleotide Exchange Factor 2	Protein Coding	2
19	SRD5A1	Steroid 5 Alpha-Reductase 1	Protein Coding	2
20	SRD5A2	Steroid 5 Alpha-Reductase 2	Protein Coding	2
21	WNT1	Wnt Family Member 1	Protein Coding	2
22	WNT2	Wnt Family Member 2	Protein Coding	2
23	WNT3	Wnt Family Member 3	Protein Coding	2
24	WNT5A	Wnt Family Member 5A	Protein Coding	2
25	WNT6	Wnt Family Member 6	Protein Coding	2
26	WNT7A	Wnt Family Member 7A	Protein Coding	2
27	WNT7B	Wnt Family Member 7B	Protein Coding	2
28	WNT8A	Wnt Family Member 8A	Protein Coding	2
29	WNT8B	Wnt Family Member 8B	Protein Coding	2
30	WNT10B	Wnt Family Member 10B	Protein Coding	2
31	WNT11	Wnt Family Member 11	Protein Coding	2
32	WNT2B	Wnt Family Member 2B	Protein Coding	2
33	WNT9A	Wnt Family Member 9A	Protein Coding	2
34	WNT9B	Wnt Family Member 9B	Protein Coding	2
35	FZD5	Frizzled Class Receptor 5	Protein Coding	2
36	FZD3	Frizzled Class Receptor 3	Protein Coding	2
37	FZD1	Frizzled Class Receptor 1	Protein Coding	2
38	FZD4	Frizzled Class Receptor 4	Protein Coding	2
39	FZD6	Frizzled Class Receptor 6	Protein Coding	2
40	FZD7	Frizzled Class Receptor 7	Protein Coding	2
41	FZD8	Frizzled Class Receptor 8	Protein Coding	2
42	FZD9	Frizzled Class Receptor 9	Protein Coding	2
43	FZD10	Frizzled Class Receptor 10	Protein Coding	2
44	WNT16	Wnt Family Member 16	Protein Coding	2
45	WNT4	Wnt Family Member 4	Protein Coding	2
46	WNT10A	Wnt Family Member 10A	Protein Coding	2
47	WNT5B	Wnt Family Member 5B	Protein Coding	2
48	WNT3A	Wnt Family Member 3A	Protein Coding	2
49	KLK3	Kallikrein Related Peptidase 3	Protein Coding	1
50	CCND1	Cyclin D1	Protein Coding	1
51	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	1
52	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
53	PTK2B	Protein Tyrosine Kinase 2 Beta	Protein Coding	1
54	IGF1	Insulin Like Growth Factor 1	Protein Coding	1
55	IGF1R	Insulin Like Growth Factor 1 Receptor	Protein Coding	1
56	IL6	Interleukin 6	Protein Coding	1
57	IL6R	Interleukin 6 Receptor	Protein Coding	1
58	IL6ST	Interleukin 6 Cytokine Family Signal Transducer	Protein Coding	1
59	SMAD3	SMAD Family Member 3	Protein Coding	1
60	MMP2	Matrix Metallopeptidase 2	Protein Coding	1
61	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	1
62	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	1
63	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	1
64	RAD9A	RAD9 Checkpoint Clamp Component A	Protein Coding	1
65	STAT3	Signal Transducer And Activator Of Transcription 3	Protein Coding	1
66	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1
67	TGFB1I1	Transforming Growth Factor Beta 1 Induced Transcript 1	Protein Coding	1
68	TGFBR1	Transforming Growth Factor Beta Receptor 1	Protein Coding	1
69	TGFBR2	Transforming Growth Factor Beta Receptor 2	Protein Coding	1
70	EZR	Ezrin	Protein Coding	1
71	NCOA1	Nuclear Receptor Coactivator 1	Protein Coding	1
72	NCOR1	Nuclear Receptor Corepressor 1	Protein Coding	1
73	NCOA2	Nuclear Receptor Coactivator 2	Protein Coding	1
74	SCAP	SREBF Chaperone	Protein Coding	1
75	PAK6	P21 (RAC1) Activated Kinase 6	Protein Coding	1
76	RAD9B	RAD9 Checkpoint Clamp Component B	Protein Coding	1
77	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	1
78	CAV1	Caveolin 1	Protein Coding	1
79	HBEGF	Heparin Binding EGF Like Growth Factor	Protein Coding	1
80	EIF4EBP1	Eukaryotic Translation Initiation Factor 4E Binding Protein 1	Protein Coding	1
81	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	1
82	FOXO3	Forkhead Box O3	Protein Coding	1
83	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	1
84	NRG1	Neuregulin 1	Protein Coding	1
85	IRS1	Insulin Receptor Substrate 1	Protein Coding	1
86	MDM2	MDM2 Proto-Oncogene	Protein Coding	1
87	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
88	NFKB2	Nuclear Factor Kappa B Subunit 2	Protein Coding	1
89	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
90	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	1
91	PTEN	Phosphatase And Tensin Homolog	Protein Coding	1
92	REL	REL Proto-Oncogene, NF-KB Subunit	Protein Coding	1
93	RELA	RELA Proto-Oncogene, NF-KB Subunit	Protein Coding	1
94	RELB	RELB Proto-Oncogene, NF-KB Subunit	Protein Coding	1
95	RPS6KB1	Ribosomal Protein S6 Kinase B1	Protein Coding	1
96	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
97	TSC2	TSC Complex Subunit 2	Protein Coding	1
98	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	1

Disorders associated with Transcription Androgen Receptor nuclear signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Robinow syndrome, autosomal dominant 1	Enrichment	DVL1, DVL3, FZD2, WNT5A	9.18
2	Autosomal dominant robinow syndrome	Enrichment	DVL1, DVL3, FZD2, WNT5A	9.18
3	Lung non-small cell carcinoma	Enrichment	EGFR, ERBB2, HRAS, MAP2K1, PIK3CA	8.84
4	Robinow syndrome, autosomal recessive 1	Enrichment	DVL1, DVL3, FZD2, WNT5A	8.49
5	Hemimegalencephaly	Enrichment	AKT3, MTOR, PIK3CA, PTEN	8.49
6	Bladder cancer	Enrichment	CTNNB1, EGFR, ERBB2, HRAS, PIK3CA, PTEN	8.18
7	Autosomal recessive robinow syndrome	Enrichment	DVL1, DVL3, FZD2, WNT5A	8.01
8	Ovarian cancer	Enrichment	AKT1, AR, CTNNB1, EGFR, ERBB2, PIK3CA, PTEN, TSC2	7.34
9	Adult hepatocellular carcinoma	Enrichment	CTNNB1, EGF, PIK3CA, TSC2	7.09
10	Noonan syndrome 1	Enrichment	HRAS, MAP2K1, RAF1, SOS1, SOS2	7.00
11	Rasopathy	Enrichment	HRAS, MAP2K1, RAF1, SOS1, SOS2	6.72
12	Colorectal cancer	Enrichment	AKT1, CTNNB1, ERBB2, FZD3, PIK3CA, PIK3R1, SRC	6.52
13	Noonan syndrome and noonan-related syndrome	Enrichment	HRAS, MAP2K1, RAF1, SOS1	6.07
14	Robinow syndrome, autosomal dominant 2	Enrichment	DVL1, DVL3, FZD2	5.88
15	Cowden syndrome 1	Enrichment	EGFR, PIK3CA, PTEN	5.58
16	Noonan syndrome 3	Enrichment	HRAS, RAF1, SOS1	5.34
17	Arteriovenous malformation	Enrichment	HRAS, MAP2K1, PIK3CA	4.97
18	Cowden syndrome	Enrichment	AKT1, PIK3CA, PTEN	4.97
19	Loeys-dietz syndrome	Enrichment	SMAD3, TGFBR1, TGFBR2	4.86
20	Prostate cancer	Enrichment	AR, PIK3CA, PTEN, SRD5A2	4.85
21	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS, MAP2K1, PIK3CA	4.81
22	Robinow syndrome, autosomal dominant 3	Enrichment	DVL3, FZD2	4.58
23	Meningioma	Enrichment	AKT1, PIK3CA, PTEN	4.55
24	Lip and oral cavity carcinoma	Enrichment	EGFR, HRAS, PIK3CA	4.55
25	Loeys-dietz syndrome 2	Enrichment	TGFBR1, TGFBR2	4.51
26	Osteoporosis, juvenile	Enrichment	WNT1, WNT3A	4.11
27	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	4.11
28	Loeys-dietz syndrome 1	Enrichment	TGFBR1, TGFBR2	4.03
29	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3, PIK3CA	3.81
30	Focal cortical dysplasia, type ii	Enrichment	MTOR, TSC2	3.81
31	Isolated focal cortical dysplasia type ii	Enrichment	MTOR, TSC2	3.81
32	Aortic aneurysm	Enrichment	SMAD3, TGFBR1	3.73
33	Exudative vitreoretinopathy 1	Enrichment	CTNNB1, FZD4	3.59
34	Insulin-like growth factor i	Enrichment	IGF1, IGF1R	3.51
35	Breast adenocarcinoma	Enrichment	AKT1, PIK3CA	3.41
36	Lung squamous cell carcinoma	Enrichment	EGFR, PIK3CA	3.41
37	Nevus, epidermal	Enrichment	HRAS, PIK3CA	3.27
38	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS, PTEN	3.27
39	Squamous cell carcinoma, head and neck	Enrichment	EGFR, PTEN	3.27
40	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1, PIK3CA	3.27
41	Gallbladder cancer	Enrichment	CTNNB1, PIK3CA	3.27
42	Common variable immunodeficiency	Enrichment	NFKB1, NFKB2	3.27
43	Follicular thyroid carcinoma	Enrichment	HRAS, PTEN	3.27
44	Overgrowth syndrome	Enrichment	MTOR, PIK3R1	3.27
45	Lung cancer	Enrichment	EGFR, ERBB2, PIK3CA	3.23
46	Breast cancer	Enrichment	AKT1, PIK3CA, PTEN, SHC1	3.22
47	Melanocytic nevus syndrome, congenital	Enrichment	HRAS, RAF1	3.14
48	Exudative vitreoretinopathy	Enrichment	CTNNB1, FZD4	3.14
49	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	2.96
50	Marfan syndrome	Enrichment	TGFBR1, TGFBR2	2.87
51	Gastric cancer	Enrichment	ERBB2, PIK3CA, PTEN	2.85
52	Hereditary breast carcinoma	Enrichment	AKT1, PIK3CA, PTEN	2.82
53	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	SMAD3, TGFBR1, TGFBR2	2.72
54	Osteoporosis	Enrichment	SRC, WNT1	2.64
55	Lung cancer susceptibility 3	Enrichment	EGFR, ERBB2	2.64
56	Autism spectrum disorder	Enrichment	MAP2K1, PTEN, SRD5A2, TSC2	2.62
57	Rhabdomyosarcoma	Enrichment	HRAS, PTEN	2.52
58	Arteriovenous malformations of the brain	Enrichment	EGFR, IL6	2.30
59	Ehlers-danlos syndrome	Enrichment	SMAD3, TGFBR2	2.30
60	Microcephaly	Enrichment	CTNNB1, EP300, IGF1R, MAPK1	2.30
61	Macrodactyly	Enrichment	PIK3CA	2.29
62	Proteus syndrome	Enrichment	AKT1	2.29
63	Paget disease, extramammary	Enrichment	ERBB2	2.29
64	Nail disorder, nonsyndromic congenital, 1	Enrichment	FZD6	2.29
65	Mullerian aplasia and hyperandrogenism	Enrichment	WNT4	2.29
66	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	2.29
67	Prostate cancer, hereditary, x-linked 3	Enrichment	AR	2.29
68	Vacterl association with hydrocephalus	Enrichment	PTEN	2.29
69	Androgen insensitivity, partial	Enrichment	AR	2.29
70	Noonan syndrome 5	Enrichment	RAF1	2.29
71	Hypomagnesemia 4, renal	Enrichment	EGF	2.29
72	Noonan syndrome 4	Enrichment	SOS1	2.29
73	Lipodystrophy, congenital generalized, type 3	Enrichment	CAV1	2.29
74	46,xx sex reversal with dysgenesis of kidneys, adrenals, and lungs	Enrichment	WNT4	2.29
75	Melorheostosis, isolated	Enrichment	MAP2K1	2.29
76	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.29
77	Omodysplasia 2	Enrichment	FZD2	2.29
78	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.29
79	Cowden syndrome 5	Enrichment	PIK3CA	2.29
80	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.29
81	Split-hand/foot malformation 6	Enrichment	WNT10B	2.29
82	Noonan syndrome 9	Enrichment	SOS2	2.29
83	Tooth agenesis, selective, 8	Enrichment	WNT10B	2.29
84	Accelerated tumor formation	Enrichment	MDM2	2.29
85	Pulmonary hypertension, primary, 3	Enrichment	CAV1	2.29
86	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.29
87	Visceral neuropathy, familial, 2, autosomal recessive	Enrichment	ERBB2	2.29
88	Noonan syndrome 13	Enrichment	MAPK1	2.29
89	Immunodeficiency 92	Enrichment	REL	2.29
90	Lessel-kubisch syndrome	Enrichment	MDM2	2.29
91	Short syndrome	Enrichment	PIK3R1	2.29
92	Diarrhea 9	Enrichment	WNT2B	2.29
93	Papillary tumor of the pineal region	Enrichment	PTEN	2.29
94	Lipodystrophy, familial partial, type 7	Enrichment	CAV1	2.29
95	Bone mineral density quantitative trait locus 16	Enrichment	WNT1	2.29
96	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	2.29
97	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.29
98	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.29
99	Santos syndrome	Enrichment	WNT7A	2.29
100	Melorheostosis	Enrichment	MAP2K1	2.29
101	Leopard syndrome 2	Enrichment	RAF1	2.29
102	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.29
103	Cowden syndrome 6	Enrichment	AKT1	2.29
104	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.29
105	Microphthalmia/coloboma 11	Enrichment	FZD5	2.29
106	Glioma susceptibility 2	Enrichment	PTEN	2.29
107	Thrombocytopenia 6	Enrichment	SRC	2.29
108	46,xy disorder of sex development due to 5-alpha-reductase 2 deficiency	Enrichment	SRD5A2	2.29
109	Deficiency in anterior pituitary function - variable immunodeficiency syndrome	Enrichment	NFKB2	2.29
110	Immunodeficiency 53	Enrichment	RELB	2.29
111	Trigonitis	Enrichment	RAF1	2.29
112	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.29
113	Adenoid ameloblastoma	Enrichment	CTNNB1	2.29
114	Hypospadias	Enrichment	PIK3CA	2.29
115	Capillary hemangioma	Enrichment	AKT3	2.29
116	Rare venous malformation	Enrichment	PIK3CA	2.29
117	Diaphragmatic eventration	Enrichment	PIK3CA	2.29
118	Complete androgen insensitivity syndrome	Enrichment	AR	2.29
119	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.29
120	Rare combined vascular malformation	Enrichment	PIK3CA	2.29
121	Cavernous lymphangioma	Enrichment	PIK3CA	2.29
122	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.29
123	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.29
124	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	2.29
125	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.29
126	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.29
127	Egf-related primary hypomagnesemia with intellectual disability	Enrichment	EGF	2.29
128	Macrodactyly of toe	Enrichment	PIK3CA	2.29
129	Serous carcinoma of the corpus uteri	Enrichment	ERBB2	2.29
130	Microcystic stromal tumor	Enrichment	CTNNB1	2.29
131	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	2.29
132	Endometrial cancer	Enrichment	PIK3CA, PTEN	2.29
133	Multiple self-healing squamous epithelioma	Enrichment	TGFBR1	2.25
134	Stuve-wiedemann syndrome 2	Enrichment	IL6ST	2.25
135	Hyper-ige syndrome 4a, autosomal dominant, with recurrent infections	Enrichment	IL6ST	2.25
136	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	2.25
137	T-cell large granular lymphocyte leukemia	Enrichment	STAT3	2.25
138	Colorectal cancer, hereditary nonpolyposis, type 6	Enrichment	TGFBR2	2.25
139	Interleukin 6, serum level of, quantitative trait locus	Enrichment	IL6R	2.25
140	Soluble interleukin-6 receptor, serum level of, quantitative trait locus	Enrichment	IL6R	2.25
141	Hyper-ige syndrome 5, autosomal recessive, with recurrent infections	Enrichment	IL6R	2.25
142	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	2.25
143	Autoimmune disease, multisystem, infantile-onset, 1	Enrichment	STAT3	2.25
144	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	2.25
145	Hyper-ige syndrome 4b, autosomal recessive, with recurrent infections	Enrichment	IL6ST	2.25
146	Immunodeficiency 94 with autoinflammation and dysmorphic facies	Enrichment	IL6ST	2.25
147	Stat3-related early-onset multisystem autoimmune disease	Enrichment	STAT3	2.25
148	Chronic lymphoproliferative disorder of natural killer cells	Enrichment	STAT3	2.25
149	Hepatocellular carcinoma	Enrichment	CTNNB1, PIK3CA	2.25
150	Tooth agenesis	Enrichment	WNT10A, WNT10B	2.25
151	Hydrops fetalis, nonimmune	Enrichment	FZD6, HRAS	2.10
152	Fibromatosis, gingival, 1	Enrichment	SOS1	1.99
153	Tooth agenesis, selective, 4	Enrichment	WNT10A	1.99
154	Costello syndrome	Enrichment	HRAS	1.99
155	Schopf-schulz-passarge syndrome	Enrichment	WNT10A	1.99
156	Spinal and bulbar muscular atrophy, x-linked 1	Enrichment	AR	1.99
157	Ulna and fibula, absence of, with severe limb deficiency	Enrichment	WNT7A	1.99
158	Bladder exstrophy and epispadias complex	Enrichment	WNT3	1.99
159	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	1.99
160	Odontoonychodermal dysplasia	Enrichment	WNT10A	1.99
161	Pulmonic stenosis	Enrichment	SOS1	1.99
162	Xanthinuria, type i	Enrichment	SRD5A2	1.99
163	Tetraamelia syndrome 1	Enrichment	WNT3	1.99
164	Lymphangioleiomyomatosis	Enrichment	TSC2	1.99
165	Keratosis, seborrheic	Enrichment	PIK3CA	1.99
166	Osteogenesis imperfecta, type xv	Enrichment	WNT1	1.99
167	Noonan syndrome 8	Enrichment	PIK3CA	1.99
168	Fibular aplasia or hypoplasia, femoral bowing, and poly-, syn-, and oligodactyly	Enrichment	WNT7A	1.99
169	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	1.99
170	Immunodeficiency, common variable, 10	Enrichment	NFKB2	1.99
171	46,xy sex reversal 1	Enrichment	AR	1.99
172	Androgen insensitivity syndrome	Enrichment	AR	1.99
173	Autoinflammatory disease, familial, behcet-like 3	Enrichment	RELA	1.99
174	Cebalid syndrome	Enrichment	MTOR	1.99
175	Hypospadias 1, x-linked	Enrichment	AR	1.99
176	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	1.99
177	Rela fusion-positive ependymoma	Enrichment	RELA	1.99
178	Senior-loken syndrome 7	Enrichment	AKT3	1.99
179	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	1.99
180	Bardet-biedl syndrome 16	Enrichment	AKT3	1.99
181	Smith-kingsmore syndrome	Enrichment	MTOR	1.99
182	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.99
183	Vacterl with hydrocephalus	Enrichment	PTEN	1.99
184	Posterior hypospadias	Enrichment	AR	1.99
185	Teratoma	Enrichment	CTNNB1	1.99
186	Bladder exstrophy-epispadias-cloacal exstrophy complex	Enrichment	WNT3	1.99
187	Common variable immunodeficiency 12	Enrichment	NFKB1	1.99
188	Juvenile polyposis of infancy	Enrichment	PTEN	1.99
189	Wooly hair nevus	Enrichment	HRAS	1.99
190	Non-immune hydrops fetalis	Enrichment	FZD6, HRAS	1.96
191	Camurati-engelmann disease 1	Enrichment	TGFB1	1.95
192	Microvascular complications of diabetes 5	Enrichment	TGFBR2	1.95
193	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	1.95
194	Loeys-dietz syndrome 3	Enrichment	SMAD3	1.95
195	Menke-hennekam syndrome 2	Enrichment	EP300	1.95
196	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.95
197	Camurati-engelmann disease	Enrichment	TGFB1	1.95
198	Fibrolamellar carcinoma	Enrichment	PRKACA	1.95
199	Growth delay due to insulin-like growth factor type 1 deficiency	Enrichment	IGF1	1.95
200	Connective tissue disease	Enrichment	SMAD3, TGFBR2	1.86
201	Desmoid disease, hereditary	Enrichment	CTNNB1	1.81
202	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.81
203	Tuberous sclerosis 1	Enrichment	TSC2	1.81
204	Mullerian duct aplasia, unilateral renal agenesis, and cervicothoracic somite anomalies	Enrichment	WNT4	1.81
205	Microphthalmia, syndromic 9	Enrichment	WNT7B	1.81
206	Polycystic kidney disease, infantile severe, with tuberous sclerosis	Enrichment	TSC2	1.81
207	Tooth agenesis, selective, 2	Enrichment	WNT10A	1.81
208	Nuchal bleb, familial	Enrichment	SOS1	1.81
209	Langerhans cell histiocytosis	Enrichment	MAP2K1	1.81
210	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.81
211	Tuberous sclerosis 2	Enrichment	TSC2	1.81
212	Neonatal nephrocutaneous inflammatory syndrome	Enrichment	EGFR	1.81
213	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	1.81
214	Anus, imperforate	Enrichment	CTNNB1	1.81
215	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.81
216	Large congenital melanocytic nevus	Enrichment	HRAS	1.81
217	Desmoid tumor	Enrichment	CTNNB1	1.81
218	Dedifferentiated liposarcoma	Enrichment	MDM2	1.81
219	Hamartoma	Enrichment	TSC2	1.81
220	Nail disease	Enrichment	FZD6	1.81
221	Xanthinuria, type ii	Enrichment	TSC2	1.81
222	Immunodeficiency 14	Enrichment	PIK3R1	1.81
223	Laryngeal squamous cell carcinoma	Enrichment	PTEN	1.81
224	Spermatocytoma	Enrichment	HRAS	1.81
225	Tetraamelia syndrome	Enrichment	WNT3	1.81
226	Neonatal inflammatory skin and bowel disease	Enrichment	EGFR	1.81
227	Well-differentiated liposarcoma	Enrichment	MDM2	1.81
228	Keratoacanthoma	Enrichment	PIK3CA	1.81
229	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	STAT3	1.78
230	Stuve-wiedemann syndrome 1	Enrichment	IL6ST	1.78
231	Multicentric osteolysis, nodulosis, and arthropathy	Enrichment	MMP2	1.78
232	Breast implant-associated anaplastic large cell lymphoma	Enrichment	STAT3	1.78
233	Hyper ige syndrome	Enrichment	STAT3	1.78
234	Growth delay due to insulin-like growth factor i resistance	Enrichment	IGF1R	1.78
235	Stüve-wiedemann syndrome	Enrichment	IL6ST	1.78
236	Congenital nervous system abnormality	Enrichment	CTNNB1, PTEN, TSC2	1.76
237	Nervous system disease	Enrichment	CTNNB1, PTEN, TSC2	1.76
238	Type 2 diabetes mellitus	Enrichment	AKT2, IRS1	1.70
239	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS	1.69
240	Cardiofaciocutaneous syndrome 1	Enrichment	MAP2K1	1.69
241	Acyl-coa dehydrogenase, very long-chain, deficiency of	Enrichment	DVL2	1.69
242	Ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	WNT10A	1.69
243	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.69
244	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3	1.69
245	Immunodeficiency, common variable, 1	Enrichment	NFKB2	1.69
246	Pilomatrixoma	Enrichment	CTNNB1	1.69
247	Barrett esophagus	Enrichment	ERBB2	1.69
248	Alazami syndrome	Enrichment	CTNNB1	1.69
249	Cardiofaciocutaneous syndrome	Enrichment	MAP2K1	1.69
250	Ectodermal dysplasia	Enrichment	WNT10A	1.69
251	Retinopathy of prematurity	Enrichment	FZD4	1.69
252	Tuberous sclerosis	Enrichment	TSC2	1.69
253	Cerebrovascular disease	Enrichment	PIK3CA	1.69
254	Craniopharyngioma	Enrichment	CTNNB1	1.69
255	Noonan syndrome with multiple lentigines	Enrichment	RAF1	1.69
256	Epidermolytic nevus	Enrichment	HRAS	1.69
257	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.69
258	Eyelid coloboma	Enrichment	FZD5	1.69
259	Glioma	Enrichment	PTEN	1.69
260	Gingival fibromatosis	Enrichment	SOS1	1.69
261	Male infertility due to gonadal dysgenesis or sperm disorder	Enrichment	SOS2	1.69
262	Lens coloboma	Enrichment	FZD5	1.69
263	Kaposi sarcoma	Enrichment	IL6	1.65
264	Mantle cell lymphoma	Enrichment	CCND1	1.65
265	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	1.65
266	Capillary malformations, congenital	Enrichment	PIK3CA	1.59
267	Pseudovaginal perineoscrotal hypospadias	Enrichment	SRD5A2	1.59
268	Norrie disease	Enrichment	FZD4	1.59
269	Macrocephaly/autism syndrome	Enrichment	PTEN	1.59
270	Hemangioma	Enrichment	PTEN	1.59
271	Persistent hyperplastic primary vitreous	Enrichment	FZD4	1.59
272	Acute megakaryocytic leukemia	Enrichment	PTEN	1.59
273	Autosomal recessive hypohidrotic ectodermal dysplasia syndrome	Enrichment	WNT10A	1.59
274	Coloboma of choroid and retina	Enrichment	FZD5	1.59
275	Diffuse cutaneous systemic sclerosis	Enrichment	CAV1	1.59
276	Von hippel-lindau syndrome	Enrichment	CCND1	1.56
277	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.56
278	Mosaic variegated aneuploidy syndrome 1	Enrichment	PAK6	1.56
279	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.56
280	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	1.51
281	Li-fraumeni syndrome	Enrichment	MDM2	1.51
282	Coloboma of optic nerve	Enrichment	FZD5	1.51
283	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.51
284	Hemihyperplasia, isolated	Enrichment	PIK3CA	1.51
285	Renal dysplasia, cystic	Enrichment	WNT9B	1.51
286	Renal hypoplasia	Enrichment	WNT9B	1.51
287	Diarrhea	Enrichment	WNT2B	1.51
288	Adrenocortical carcinoma	Enrichment	CTNNB1	1.51
289	Limited scleroderma	Enrichment	CAV1	1.51
290	Multicystic kidney dysplasia	Enrichment	FZD3	1.51
291	Multicystic dysplastic kidney	Enrichment	FZD3	1.51
292	Inherited cancer-predisposing syndrome	Enrichment	EGFR, PTEN, TSC2	1.51
293	Rubinstein-taybi syndrome 1	Enrichment	EP300	1.48
294	Type 1 diabetes mellitus	Enrichment	IL6	1.48
295	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	EP300	1.48
296	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	1.48
297	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	1.48
298	Classic ehlers-danlos syndrome	Enrichment	TGFBR1	1.48
299	Polycystic kidney disease 1 with or without polycystic liver disease	Enrichment	TSC2	1.45
300	Myelofibrosis	Enrichment	SRC	1.45
301	Coats disease	Enrichment	FZD4	1.45
302	Renal cell carcinoma, papillary, 1	Enrichment	MTOR	1.45
303	Polycystic kidney disease 1	Enrichment	TSC2	1.45
304	Pilomyxoid astrocytoma	Enrichment	RAF1	1.45
305	Megacolon	Enrichment	AKT3	1.45
306	Esophageal cancer	Enrichment	TGFBR2	1.41
307	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A	1.41
308	Glioma susceptibility 1	Enrichment	ERBB2	1.39
309	Renal hypodysplasia/aplasia 1	Enrichment	WNT9B	1.39
310	Isolated split hand-split foot malformation	Enrichment	WNT10B	1.39
311	Difference of sex development	Enrichment	AR	1.39
312	Mosaic variegated aneuploidy syndrome	Enrichment	PAK6	1.36
313	Permanent neonatal diabetes mellitus	Enrichment	STAT3	1.36
314	Renal agenesis, bilateral	Enrichment	WNT9B	1.34
315	Charge syndrome	Enrichment	EP300	1.31
316	Inflammatory bowel disease 1	Enrichment	IL6	1.31
317	Familial thoracic aortic aneurysm and dissection	Enrichment	SMAD3	1.31
318	Cat eye syndrome	Enrichment	FZD5	1.30
319	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.30
320	Polymicrogyria	Enrichment	AKT3	1.30
321	Melanoma	Enrichment	PTEN	1.30
322	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1	1.30
323	Leukemia, chronic lymphocytic	Enrichment	CCND1	1.26
324	Meningioma, familial	Enrichment	PTEN	1.26
325	46,xy complete gonadal dysgenesis	Enrichment	AR	1.26
326	Uterine corpus cancer	Enrichment	PTEN	1.26
327	Heritable pulmonary arterial hypertension	Enrichment	CAV1	1.26
328	Specific learning disability	Enrichment	MAPK1	1.26
329	Pectus excavatum	Enrichment	TGFBR1	1.22
330	Aortic valve disease 1	Enrichment	SOS1	1.19
331	Microphthalmia/coloboma 12	Enrichment	FZD5	1.19
332	Osteogenesis imperfecta, type iv	Enrichment	WNT1	1.19
333	Chronic kidney disease	Enrichment	WNT9B	1.19
334	Medulloblastoma	Enrichment	CTNNB1	1.16
335	46,xy partial gonadal dysgenesis	Enrichment	SOS1	1.16
336	Neural tube defects	Enrichment	RAD9B	1.15
337	Acute promyelocytic leukemia	Enrichment	STAT3	1.15
338	Nk-cell enteropathy	Enrichment	IGF1R	1.15
339	Coloboma of macula	Enrichment	FZD5	1.13
340	Renal cell carcinoma, nonpapillary	Enrichment	MTOR	1.13
341	Osteogenesis imperfecta, type iii	Enrichment	WNT1	1.13
342	Hydrocephalus	Enrichment	FZD3	1.13
343	Lynch syndrome	Enrichment	PIK3CA	1.13
344	Autosomal dominant polycystic kidney disease	Enrichment	TSC2	1.13
345	Rare genetic intellectual disability	Enrichment	MTOR	1.13
346	Aortic aneurysm, familial thoracic 1	Enrichment	SMAD3	1.12
347	Gliosarcoma	Enrichment	EGFR	1.10
348	Polydactyly, postaxial, type a1	Enrichment	EP300	1.09
349	Polycystic liver disease	Enrichment	CTNNB1	1.07
350	Giant cell glioblastoma	Enrichment	EGFR	1.07
351	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	1.07
352	Heart, malformation of	Enrichment	MAPK1	1.05
353	Diffuse large b-cell lymphoma	Enrichment	PTEN	1.03
354	Macs syndrome	Enrichment	WNT7B	1.01
355	Hepatoblastoma	Enrichment	CTNNB1	0.99
356	Microphthalmia	Enrichment	WNT7B	0.97
357	Brittle bone disorder	Enrichment	WNT1	0.95
358	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	0.93
359	Hirschsprung disease 1	Enrichment	ERBB2	0.86
360	Differentiated thyroid carcinoma	Enrichment	HRAS	0.86
361	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.80
362	Male infertility	Enrichment	AR	0.79
363	Cystic fibrosis	Enrichment	TGFB1	0.78
364	Left ventricular noncompaction	Enrichment	RAF1	0.78
365	Distal arthrogryposis	Enrichment	FZD3	0.71
366	West syndrome	Enrichment	TSC2	0.69
367	Thrombocytopenia	Enrichment	SRC	0.66
368	Hypertelorism	Enrichment	PIK3CA	0.63
369	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	0.62
370	Hereditary breast ovarian cancer syndrome	Enrichment	PTEN	0.61
371	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	AR	0.60
372	Myeloma, multiple	Enrichment	CCND1	0.57
373	Autosomal recessive non-syndromic intellectual disability	Enrichment	EZR	0.56
374	Dilated cardiomyopathy	Enrichment	RAF1	0.47
375	Hereditary retinal dystrophy	Enrichment	FZD4	0.11
376	Fundus dystrophy	Enrichment	FZD4	0.11

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Transcription Androgen Receptor nuclear signaling

Pathway Network for Transcription Androgen Receptor nuclear signaling

Member Pathways for Transcription Androgen Receptor nuclear signaling

Pathways in the Transcription Androgen Receptor nuclear signaling SuperPath

Associated Genes for Transcription Androgen Receptor nuclear signaling

Associated Disorders for Transcription Androgen Receptor nuclear signaling

Disorders associated with Transcription Androgen Receptor nuclear signaling SuperPath

STRING Interaction Network for Transcription Androgen Receptor nuclear signaling

Sources for Transcription Androgen Receptor nuclear signaling