Transcription_Transcription factor Tubby signaling pathways

No Pathway Network information available for Transcription_Transcription factor Tubby signaling pathways

Pathways in the Transcription_Transcription factor Tubby signaling pathways SuperPath

#	Name	Source	Genes
1	Transcription_Transcription factor Tubby signaling pathways	GeneGo (Thomson Reuters)	ABL1 GNA11 GNAQ HTR2C INS INSR JAK2 PLCB1 PLCB2 PLCB3 PLCB4 PLCG1 PLCG2 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD2 PRKD3 TUB (see all 26) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ABL1	ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase	Protein Coding	1
2	GNA11	G Protein Subunit Alpha 11	Protein Coding	1
3	GNAQ	G Protein Subunit Alpha Q	Protein Coding	1
4	HTR2C	5-Hydroxytryptamine Receptor 2C	Protein Coding	1
5	INS	Insulin	Protein Coding	1
6	INSR	Insulin Receptor	Protein Coding	1
7	JAK2	Janus Kinase 2	Protein Coding	1
8	PLCB2	Phospholipase C Beta 2	Protein Coding	1
9	PLCB3	Phospholipase C Beta 3	Protein Coding	1
10	PLCB4	Phospholipase C Beta 4	Protein Coding	1
11	PLCG1	Phospholipase C Gamma 1	Protein Coding	1
12	PLCG2	Phospholipase C Gamma 2	Protein Coding	1
13	PRKCA	Protein Kinase C Alpha	Protein Coding	1
14	PRKCB	Protein Kinase C Beta	Protein Coding	1
15	PRKCD	Protein Kinase C Delta	Protein Coding	1
16	PRKCE	Protein Kinase C Epsilon	Protein Coding	1
17	PRKCG	Protein Kinase C Gamma	Protein Coding	1
18	PRKCH	Protein Kinase C Eta	Protein Coding	1
19	PRKCI	Protein Kinase C Iota	Protein Coding	1
20	PRKD1	Protein Kinase D1	Protein Coding	1
21	PRKCQ	Protein Kinase C Theta	Protein Coding	1
22	PRKCZ	Protein Kinase C Zeta	Protein Coding	1
23	TUB	TUB Bipartite Transcription Factor	Protein Coding	1
24	PLCB1	Phospholipase C Beta 1	Protein Coding	1
25	PRKD3	Protein Kinase D3	Protein Coding	1
26	PRKD2	Protein Kinase D2	Protein Coding	1

Disorders associated with Transcription_Transcription factor Tubby signaling pathways SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Melanoma, uveal	Enrichment	GNA11, GNAQ, PLCB4	6.90
2	Phakomatosis cesioflammea	Enrichment	GNA11, GNAQ	5.45
3	Anastomosing haemangioma	Enrichment	GNA11, GNAQ	4.98
4	Capillary malformations, congenital	Enrichment	GNA11, GNAQ	4.45
5	Hypocalciuric hypercalcemia, familial, type ii	Enrichment	GNA11	2.72
6	Donohue syndrome	Enrichment	INSR	2.72
7	Hyperinsulinemic hypoglycemia, familial, 5	Enrichment	INSR	2.72
8	Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities	Enrichment	INSR	2.72
9	Diabetes mellitus, insulin-resistant, with acanthosis nigricans	Enrichment	INSR	2.72
10	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	2.72
11	Sturge-weber syndrome	Enrichment	GNAQ	2.72
12	Spondylometaphyseal dysplasia with corneal dystrophy	Enrichment	PLCB3	2.72
13	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	2.72
14	Auriculocondylar syndrome 2a	Enrichment	PLCB4	2.72
15	Spinocerebellar ataxia 14	Enrichment	PRKCG	2.72
16	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	2.72
17	Hypocalcemia, autosomal dominant 2	Enrichment	GNA11	2.72
18	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	2.72
19	Congenital heart defects and ectodermal dysplasia	Enrichment	PRKD1	2.72
20	Auriculocondylar syndrome 2b	Enrichment	PLCB4	2.72
21	Phakomatosis cesiomarmorata	Enrichment	GNA11	2.72
22	Malignant epithelial tumor of salivary glands	Enrichment	PRKD1	2.72
23	Cutis marmorata telangiectatica congenita	Enrichment	GNA11	2.42
24	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	INSR	2.42
25	Maturity-onset diabetes of the young, type 10	Enrichment	INS	2.42
26	Thrombocythemia 3	Enrichment	JAK2	2.42
27	Hyperproinsulinemia	Enrichment	INS	2.42
28	Congenital heart defects and skeletal malformations syndrome	Enrichment	ABL1	2.42
29	Autosomal dominant hypocalcemia	Enrichment	GNA11	2.42
30	Ocular melanoma	Enrichment	PLCB4	2.42
31	Diabetes mellitus, permanent neonatal, 4	Enrichment	INS	2.42
32	Retinal dystrophy and obesity	Enrichment	TUB	2.42
33	Polycythemia	Enrichment	JAK2	2.42
34	Hypereosinophilic syndrome	Enrichment	JAK2	2.42
35	Type 1 diabetes mellitus 2	Enrichment	INS	2.24
36	Polycythemia vera	Enrichment	JAK2	2.24
37	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	GNA11	2.24
38	Breast implant-associated anaplastic large cell lymphoma	Enrichment	JAK2	2.24
39	T-cell acute lymphoblastic leukemia	Enrichment	ABL1	2.24
40	Erythrocytosis, familial, 1	Enrichment	JAK2	2.12
41	Budd-chiari syndrome	Enrichment	JAK2	2.12
42	Auriculocondylar syndrome 1	Enrichment	PLCB4	2.12
43	Developmental and epileptic encephalopathy 12	Enrichment	PLCB1	2.12
44	Neonatal diabetes mellitus	Enrichment	INS	2.12
45	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	ABL1	2.12
46	Hereditary ataxia	Enrichment	PRKCG	2.12
47	Myeloproliferative neoplasm	Enrichment	JAK2	2.02
48	Klippel-trenaunay-weber syndrome	Enrichment	GNAQ	1.94
49	Type 1 diabetes mellitus	Enrichment	INS	1.94
50	46,xy disorder of sex development	Enrichment	INSR	1.94
51	Myelofibrosis	Enrichment	JAK2	1.87
52	Leukemia, chronic myeloid	Enrichment	ABL1	1.87
53	Essential thrombocythemia	Enrichment	JAK2	1.87
54	Moyamoya angiopathy	Enrichment	ABL1	1.87
55	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	ABL1	1.87
56	Permanent neonatal diabetes mellitus	Enrichment	INS	1.82
57	Inflammatory bowel disease 1	Enrichment	PRKCQ	1.77
58	Leukemia, acute lymphoblastic 3	Enrichment	JAK2	1.77
59	Developmental and epileptic encephalopathy 14	Enrichment	PLCB1	1.77
60	Stroke, ischemic	Enrichment	PRKCH	1.72
61	Diabetes mellitus	Enrichment	INS	1.68
62	Lip and oral cavity carcinoma	Enrichment	ABL1	1.64
63	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ	1.61
64	Heart disease	Enrichment	ABL1	1.58
65	Maturity-onset diabetes of the young	Enrichment	INS	1.42
66	Precursor t-cell acute lymphoblastic leukemia	Enrichment	ABL1	1.36
67	Leukemia, acute myeloid	Enrichment	JAK2	1.13
68	Benign epilepsy with centrotemporal spikes	Enrichment	PLCB1	1.12
69	Type 2 diabetes mellitus	Enrichment	INSR	1.11
70	Centralopathic epilepsy	Enrichment	PLCB1	1.10
71	West syndrome	Enrichment	PLCB1	1.09
72	Primary ovarian insufficiency	Enrichment	JAK2	0.97
73	Microcephaly	Enrichment	ABL1	0.68
74	Retinitis pigmentosa	Enrichment	TUB	0.47
75	Hereditary retinal dystrophy	Enrichment	TUB	0.37
76	Fundus dystrophy	Enrichment	TUB	0.37

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Transcription_Transcription factor Tubby signaling pathways

Pathway Network for Transcription_Transcription factor Tubby signaling pathways

Member Pathways for Transcription_Transcription factor Tubby signaling pathways

Pathways in the Transcription_Transcription factor Tubby signaling pathways SuperPath

Associated Genes for Transcription_Transcription factor Tubby signaling pathways

Associated Disorders for Transcription_Transcription factor Tubby signaling pathways

Disorders associated with Transcription_Transcription factor Tubby signaling pathways SuperPath

STRING Interaction Network for Transcription_Transcription factor Tubby signaling pathways

Sources for Transcription_Transcription factor Tubby signaling pathways