Transcriptional activation of cell cycle inhibitor p21

No Pathway Network information available for Transcriptional activation of cell cycle inhibitor p21

Pathways in the Transcriptional activation of cell cycle inhibitor p21 SuperPath

#	Name	Source	Genes
1	Transcriptional activation of cell cycle inhibitor p21	Reactome	CDKN1A PCBP4 TP53 ZNF385A
2	Transcriptional activation of p53 responsive genes	Reactome	CDKN1A PCBP4 TP53 ZNF385A

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	2
2	ZNF385A	Zinc Finger Protein 385A	Protein Coding	2
3	PCBP4	Poly(RC) Binding Protein 4	Protein Coding	2
4	TP53	Tumor Protein P53	Protein Coding	2

Disorders associated with Transcriptional activation of cell cycle inhibitor p21 SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Bladder cancer	Enrichment	CDKN1A, TP53	4.58
2	Bone marrow failure syndrome 5	Enrichment	TP53	3.53
3	Papilloma of choroid plexus	Enrichment	TP53	3.53
4	Basal cell carcinoma 7	Enrichment	TP53	3.53
5	Anaplastic thyroid carcinoma	Enrichment	TP53	3.53
6	Ductal carcinoma in situ	Enrichment	TP53	3.53
7	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	3.53
8	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	3.53
9	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	3.53
10	Choroid plexus cancer	Enrichment	TP53	3.53
11	Pleomorphic xanthoastrocytoma	Enrichment	TP53	3.53
12	Adrenocortical carcinoma, hereditary	Enrichment	TP53	3.23
13	Cervical cancer	Enrichment	TP53	3.23
14	Lymphoma, hodgkin, classic	Enrichment	TP53	3.23
15	Congenital fibrosarcoma	Enrichment	TP53	3.23
16	Li-fraumeni syndrome 1	Enrichment	TP53	3.23
17	Sarcoma	Enrichment	TP53	3.23
18	Cervix carcinoma	Enrichment	TP53	3.23
19	Hodgkin's lymphoma	Enrichment	TP53	3.23
20	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	3.23
21	Osteogenic sarcoma	Enrichment	TP53	3.05
22	Nasopharyngeal carcinoma	Enrichment	TP53	3.05
23	Atypical teratoid rhabdoid tumor	Enrichment	TP53	3.05
24	Anaplastic astrocytoma	Enrichment	TP53	3.05
25	Squamous cell carcinoma	Enrichment	TP53	3.05
26	Adenocarcinoma	Enrichment	TP53	3.05
27	Bone osteosarcoma	Enrichment	TP53	3.05
28	Small cell cancer of the lung	Enrichment	TP53	2.93
29	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	2.93
30	Lung sarcomatoid carcinoma	Enrichment	TP53	2.93
31	Embryonal rhabdomyosarcoma	Enrichment	TP53	2.93
32	Rhabdomyosarcoma 2	Enrichment	TP53	2.83
33	Lymphoma	Enrichment	TP53	2.83
34	Acute megakaryocytic leukemia	Enrichment	TP53	2.83
35	Li-fraumeni syndrome	Enrichment	TP53	2.75
36	Adrenocortical carcinoma	Enrichment	TP53	2.75
37	Breast adenocarcinoma	Enrichment	TP53	2.75
38	Esophageal cancer	Enrichment	TP53	2.69
39	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A	2.69
40	Squamous cell carcinoma, head and neck	Enrichment	TP53	2.69
41	Essential thrombocythemia	Enrichment	TP53	2.69
42	Gallbladder cancer	Enrichment	TP53	2.69
43	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	TP53	2.69
44	Glioma susceptibility 1	Enrichment	TP53	2.63
45	Lymphoma, non-hodgkin, familial	Enrichment	TP53	2.63
46	Adult hepatocellular carcinoma	Enrichment	TP53	2.58
47	Primary hyperaldosteronism	Enrichment	TP53	2.58
48	Leukemia, chronic lymphocytic	Enrichment	TP53	2.53
49	Familial colorectal cancer	Enrichment	TP53	2.53
50	Myelodysplastic syndrome	Enrichment	TP53	2.49
51	Lip and oral cavity carcinoma	Enrichment	TP53	2.45
52	Lung cancer susceptibility 3	Enrichment	TP53	2.38
53	Rhabdomyosarcoma	Enrichment	TP53	2.33
54	Gliosarcoma	Enrichment	TP53	2.33
55	Giant cell glioblastoma	Enrichment	TP53	2.30
56	Diffuse large b-cell lymphoma	Enrichment	TP53	2.25
57	Hepatoblastoma	Enrichment	TP53	2.21
58	Hepatocellular carcinoma	Enrichment	TP53	2.19
59	Diamond-blackfan anemia 1	Enrichment	TP53	2.17
60	Pancreatic cancer	Enrichment	TP53	2.13
61	Prostate cancer	Enrichment	TP53	2.07
62	Diamond-blackfan anemia	Enrichment	TP53	1.98
63	Leukemia, acute myeloid	Enrichment	TP53	1.93
64	Gastric cancer	Enrichment	TP53	1.90
65	Hereditary breast carcinoma	Enrichment	TP53	1.89
66	Hereditary breast ovarian cancer syndrome	Enrichment	TP53	1.79
67	Myeloma, multiple	Enrichment	TP53	1.78
68	Breast cancer	Enrichment	TP53	1.66
69	Colorectal cancer	Enrichment	TP53	1.59
70	Ovarian cancer	Enrichment	TP53	1.53
71	Inherited cancer-predisposing syndrome	Enrichment	TP53	1.42

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Transcriptional activation of cell cycle inhibitor p21

Pathway Network for Transcriptional activation of cell cycle inhibitor p21

Member Pathways for Transcriptional activation of cell cycle inhibitor p21

Pathways in the Transcriptional activation of cell cycle inhibitor p21 SuperPath

Associated Genes for Transcriptional activation of cell cycle inhibitor p21

Associated Disorders for Transcriptional activation of cell cycle inhibitor p21

Disorders associated with Transcriptional activation of cell cycle inhibitor p21 SuperPath

STRING Interaction Network for Transcriptional activation of cell cycle inhibitor p21

Sources for Transcriptional activation of cell cycle inhibitor p21