Transcriptional Regulation by E2F6

No Pathway Network information available for Transcriptional Regulation by E2F6

Pathways in the Transcriptional Regulation by E2F6 SuperPath

#	Name	Source	Genes
1	Transcriptional Regulation by E2F6	Reactome	BMI1 BRCA1 CBX3 CBX5 CDC7 CHEK1 COMMD3-BMI1 E2F1 E2F6 EED EHMT1 EHMT2 EPC1 EZH2 L3MBTL2 MAX MGA PCGF2 PCGF6 PHC1 PHC3 RAD51 RBBP4 RBBP7 RBBP8 RING1 RNF2 RRM2 RYBP SUZ12 TFDP1 TFDP2 UXT YAF2 (see all 34) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	COMMD3-BMI1	COMMD3-BMI1 Readthrough	Protein Coding	1
2	YAF2	YY1 Associated Factor 2	Protein Coding	1
3	EHMT2	Euchromatic Histone Lysine Methyltransferase 2	Protein Coding	1
4	CHEK1	Checkpoint Kinase 1	Protein Coding	1
5	CBX3	Chromobox 3	Protein Coding	1
6	E2F1	E2F Transcription Factor 1	Protein Coding	1
7	E2F6	E2F Transcription Factor 6	Protein Coding	1
8	PHC1	Polyhomeotic Homolog 1	Protein Coding	1
9	EZH2	Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit	Protein Coding	1
10	MGA	MAX Dimerization Protein MGA	Protein Coding	1
11	RYBP	RING1 And YY1 Binding Protein	Protein Coding	1
12	CBX5	Chromobox 5	Protein Coding	1
13	SUZ12	SUZ12 Polycomb Repressive Complex 2 Subunit	Protein Coding	1
14	MAX	MYC Associated Transcriptional Regulator X	Protein Coding	1
15	RAD51	RAD51 Recombinase	Protein Coding	1
16	RBBP4	RB Binding Protein 4, Chromatin Remodeling Factor	Protein Coding	1
17	RBBP7	RB Binding Protein 7, Chromatin Remodeling Factor	Protein Coding	1
18	RBBP8	RB Binding Protein 8, Endonuclease	Protein Coding	1
19	RING1	Ring Finger Protein 1	Protein Coding	1
20	RNF2	Ring Finger Protein 2	Protein Coding	1
21	RRM2	Ribonucleotide Reductase Regulatory Subunit M2	Protein Coding	1
22	BMI1	BMI1 Proto-Oncogene, Polycomb Ring Finger	Protein Coding	1
23	BRCA1	BRCA1 DNA Repair Associated	Protein Coding	1
24	TFDP1	Transcription Factor Dp-1	Protein Coding	1
25	TFDP2	Transcription Factor Dp-2	Protein Coding	1
26	PCGF2	Polycomb Group Ring Finger 2	Protein Coding	1
27	EHMT1	Euchromatic Histone Lysine Methyltransferase 1	Protein Coding	1
28	PHC3	Polyhomeotic Homolog 3	Protein Coding	1
29	EPC1	Enhancer Of Polycomb 1	Protein Coding	1
30	CDC7	Cell Division Cycle 7	Protein Coding	1
31	L3MBTL2	L3MBTL Histone Methyl-Lysine Binding Protein 2	Protein Coding	1
32	UXT	Ubiquitously Expressed Prefoldin Like Chaperone	Protein Coding	1
33	PCGF6	Polycomb Group Ring Finger 6	Protein Coding	1
34	EED	Embryonic Ectoderm Development	Protein Coding	1

Disorders associated with Transcriptional Regulation by E2F6 SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Weaver syndrome	Enrichment	EZH2, SUZ12	4.74
2	Pancreatic cancer	Enrichment	BRCA1, RBBP8	2.75
3	Palmoplantar keratoderma, punctate type ii	Enrichment	BRCA1	2.60
4	Spermatogenic failure, x-linked, 9	Enrichment	RBBP7	2.60
5	Seckel syndrome 2	Enrichment	RBBP8	2.60
6	Mirror movements 2	Enrichment	RAD51	2.60
7	Microcephaly 11, primary, autosomal recessive	Enrichment	PHC1	2.60
8	Luo-schoch-yamamoto syndrome	Enrichment	RNF2	2.60
9	Fanconi anemia, complementation group r	Enrichment	RAD51	2.60
10	Imagawa-matsumoto syndrome	Enrichment	SUZ12	2.60
11	Infant-type hemispheric glioma	Enrichment	BRCA1	2.60
12	Jawad syndrome	Enrichment	RBBP8	2.60
13	Polydactyly-macrocephaly syndrome	Enrichment	MAX	2.60
14	Cohen-gibson syndrome	Enrichment	EED	2.60
15	Turnpenny-fry syndrome	Enrichment	PCGF2	2.60
16	Premature ovarian failure 26	Enrichment	MGA	2.60
17	Oocyte/zygote/embryo maturation arrest 21	Enrichment	CHEK1	2.60
18	Primary peritoneal carcinoma	Enrichment	BRCA1	2.60
19	Fanconi anemia, complementation group a	Enrichment	BRCA1, RAD51	2.46
20	Inherited cancer-predisposing syndrome	Enrichment	BRCA1, EZH2, MAX	2.36
21	Fanconi anemia, complementation group s	Enrichment	BRCA1	2.30
22	Pancreatic cancer 4	Enrichment	BRCA1	2.30
23	Kleefstra syndrome	Enrichment	EHMT1	2.30
24	Inflammatory breast carcinoma	Enrichment	BRCA1	2.30
25	Peritoneum cancer	Enrichment	BRCA1	2.30
26	Bilateral breast cancer	Enrichment	BRCA1	2.30
27	Kleefstra syndrome due to a point mutation	Enrichment	EHMT1	2.30
28	Hereditary breast carcinoma	Enrichment	BRCA1, RAD51	2.27
29	Spindle cell sarcoma	Enrichment	MGA	2.12
30	Hereditary breast ovarian cancer syndrome	Enrichment	BRCA1, RAD51	2.08
31	Mirror movements 1	Enrichment	RAD51	2.00
32	Polyposis syndrome, hereditary mixed, 1	Enrichment	BRCA1	2.00
33	Cholangiocarcinoma	Enrichment	BRCA1	2.00
34	Male infertility due to gonadal dysgenesis or sperm disorder	Enrichment	CHEK1	2.00
35	Breast-ovarian cancer, familial 2	Enrichment	BRCA1	1.90
36	Ciliary dyskinesia, primary, 40	Enrichment	E2F6	1.90
37	Endometrial stromal sarcoma	Enrichment	SUZ12	1.90
38	Kleefstra syndrome 1	Enrichment	EHMT1	1.83
39	Breast cancer	Enrichment	BRCA1, RAD51	1.82
40	Polymicrogyria	Enrichment	EHMT1	1.61
41	Uterine corpus cancer	Enrichment	BRCA1	1.56
42	Autism spectrum disorder	Enrichment	EED, EHMT1	1.52
43	Breast-ovarian cancer, familial 1	Enrichment	BRCA1	1.49
44	Pheochromocytoma	Enrichment	MAX	1.46
45	Periventricular nodular heterotopia	Enrichment	BRCA1	1.46
46	Seckel syndrome	Enrichment	RBBP8	1.46
47	Rhabdomyosarcoma	Enrichment	BRCA1	1.40
48	Isolated congenital microcephaly	Enrichment	PHC1	1.40
49	Endometrial cancer	Enrichment	BRCA1	1.29
50	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	MAX	1.29
51	Bladder cancer	Enrichment	BRCA1	1.15
52	Prostate cancer	Enrichment	BRCA1	1.15
53	Lung cancer	Enrichment	BRCA1	1.11
54	Primary autosomal recessive microcephaly	Enrichment	PHC1	1.11
55	Gastric cancer	Enrichment	BRCA1	0.99
56	Myeloma, multiple	Enrichment	MGA	0.88
57	Schizophrenia	Enrichment	EHMT1	0.86
58	Colorectal cancer	Enrichment	BRCA1	0.71
59	Ovarian cancer	Enrichment	BRCA1	0.65
60	Complex neurodevelopmental disorder	Enrichment	RNF2	0.57

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Transcriptional Regulation by E2F6

Pathway Network for Transcriptional Regulation by E2F6

Member Pathways for Transcriptional Regulation by E2F6

Pathways in the Transcriptional Regulation by E2F6 SuperPath

Associated Genes for Transcriptional Regulation by E2F6

Associated Disorders for Transcriptional Regulation by E2F6

Disorders associated with Transcriptional Regulation by E2F6 SuperPath

STRING Interaction Network for Transcriptional Regulation by E2F6

Sources for Transcriptional Regulation by E2F6