Transcriptional regulation of brown and beige adipocyte differentiation

No Pathway Network information available for Transcriptional regulation of brown and beige adipocyte differentiation

Pathways in the Transcriptional regulation of brown and beige adipocyte differentiation SuperPath

#	Name	Source	Genes
1	Transcriptional regulation of brown and beige adipocyte differentiation	Reactome	BMP7 CHD3 CHD4 CIDEA COX7A1 DIO2 EBF2 ELOVL3 GATAD2A GATAD2B HDAC1 HDAC2 HNRNPU MBD3 MTA1 MTA2 MTA3 NCOA1 PPARA PPARG PPARGC1A PPARGC1B PRDM16 RBBP4 RBBP7 RXRA SMAD1 SMAD4 UCP1 ZNF423 (see all 30) (see less)
2	Transcriptional regulation of brown and beige adipocyte differentiation by EBF2	Reactome	BMP7 CHD3 CHD4 CIDEA COX7A1 DIO2 EBF2 ELOVL3 GATAD2A GATAD2B HDAC1 HDAC2 HNRNPU MBD3 MTA1 MTA2 MTA3 NCOA1 PPARA PPARG PPARGC1A PPARGC1B PRDM16 RBBP4 RBBP7 RXRA SMAD1 SMAD4 UCP1 ZNF423 (see all 30) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PPARGC1A	PPARG Coactivator 1 Alpha	Protein Coding	2
2	CHD3	Chromodomain Helicase DNA Binding Protein 3	Protein Coding	2
3	CHD4	Chromodomain Helicase DNA Binding Protein 4	Protein Coding	2
4	CIDEA	Cell Death Inducing DFFA Like Effector A	Protein Coding	2
5	PPARGC1B	PPARG Coactivator 1 Beta	Protein Coding	2
6	COX7A1	Cytochrome C Oxidase Subunit 7A1	Protein Coding	2
7	DIO2	Iodothyronine Deiodinase 2	Protein Coding	2
8	ZNF423	Zinc Finger Protein 423	Protein Coding	2
9	HDAC1	Histone Deacetylase 1	Protein Coding	2
10	HDAC2	Histone Deacetylase 2	Protein Coding	2
11	HNRNPU	Heterogeneous Nuclear Ribonucleoprotein U	Protein Coding	2
12	SMAD1	SMAD Family Member 1	Protein Coding	2
13	SMAD4	SMAD Family Member 4	Protein Coding	2
14	MBD3	Methyl-CpG Binding Domain Protein 3	Protein Coding	2
15	PPARA	Peroxisome Proliferator Activated Receptor Alpha	Protein Coding	2
16	PPARG	Peroxisome Proliferator Activated Receptor Gamma	Protein Coding	2
17	GATAD2A	GATA Zinc Finger Domain Containing 2A	Protein Coding	2
18	GATAD2B	GATA Zinc Finger Domain Containing 2B	Protein Coding	2
19	MTA3	Metastasis Associated 1 Family Member 3	Protein Coding	2
20	RBBP4	RB Binding Protein 4, Chromatin Remodeling Factor	Protein Coding	2
21	RBBP7	RB Binding Protein 7, Chromatin Remodeling Factor	Protein Coding	2
22	RXRA	Retinoid X Receptor Alpha	Protein Coding	2
23	PRDM16	PR/SET Domain 16	Protein Coding	2
24	EBF2	EBF Transcription Factor 2	Protein Coding	2
25	BMP7	Bone Morphogenetic Protein 7	Protein Coding	2
26	UCP1	Uncoupling Protein 1	Protein Coding	2
27	ELOVL3	ELOVL Fatty Acid Elongase 3	Protein Coding	2
28	NCOA1	Nuclear Receptor Coactivator 1	Protein Coding	2
29	MTA1	Metastasis Associated 1	Protein Coding	2
30	MTA2	Metastasis Associated 1 Family Member 2	Protein Coding	2

Disorders associated with Transcriptional regulation of brown and beige adipocyte differentiation SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Spermatogenic failure, x-linked, 9	Enrichment	RBBP7	2.66
2	Gand syndrome	Enrichment	GATAD2B	2.66
3	Developmental and epileptic encephalopathy 54	Enrichment	HNRNPU	2.66
4	Left ventricular noncompaction 8	Enrichment	PRDM16	2.66
5	Nephronophthisis 14	Enrichment	ZNF423	2.66
6	Severe intellectual disability-poor language-strabismus-grimacing face-long fingers syndrome	Enrichment	GATAD2B	2.66
7	Pparg-associated congenital generalized lipodystrophy	Enrichment	PPARG	2.66
8	Heritable thoracic aortic disease	Enrichment	SMAD4	2.66
9	1q44 microdeletion syndrome	Enrichment	HNRNPU	2.66
10	Myhre syndrome	Enrichment	SMAD4	2.35
11	Carotid intimal medial thickness 1	Enrichment	PPARG	2.35
12	Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome	Enrichment	SMAD4	2.35
13	Sifrim-hitz-weiss syndrome	Enrichment	CHD4	2.35
14	Snijders blok-campeau syndrome	Enrichment	CHD3	2.35
15	Familial partial lipodystrophy	Enrichment	PPARG	2.35
16	Juvenile polyposis syndrome	Enrichment	SMAD4	2.18
17	Lipodystrophy, familial partial, type 3	Enrichment	PPARG	2.05
18	Leptin deficiency or dysfunction	Enrichment	PPARG	2.05
19	Congenital generalized lipodystrophy	Enrichment	PPARG	2.05
20	Ventricular septal defect 1	Enrichment	BMP7	1.96
21	Congenital heart defects, multiple types, 4	Enrichment	BMP7	1.96
22	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	SMAD4	1.96
23	Arima syndrome	Enrichment	ZNF423	1.81
24	Gallbladder cancer	Enrichment	SMAD4	1.81
25	Hereditary hemorrhagic telangiectasia	Enrichment	SMAD4	1.81
26	Colorectal cancer	Enrichment	PPARG, SMAD4	1.80
27	Infantile nephronophthisis	Enrichment	ZNF423	1.76
28	Chromosome 1p36 deletion syndrome	Enrichment	PRDM16	1.55
29	Gliosarcoma	Enrichment	PPARG	1.46
30	Giant cell glioblastoma	Enrichment	PPARG	1.43
31	Pancreatic cancer	Enrichment	SMAD4	1.27
32	Differentiated thyroid carcinoma	Enrichment	PPARG	1.21
33	Left ventricular noncompaction	Enrichment	PRDM16	1.13
34	Type 2 diabetes mellitus	Enrichment	PPARG	1.05
35	Gastric cancer	Enrichment	SMAD4	1.04
36	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	SMAD4	1.03
37	Thrombocytopenia	Enrichment	SMAD4	1.00
38	Body mass index quantitative trait locus 11	Enrichment	PPARG	0.98
39	Familial isolated dilated cardiomyopathy	Enrichment	PRDM16	0.95
40	Myeloma, multiple	Enrichment	RXRA	0.93
41	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	PPARGC1A	0.92
42	Inherited cancer-predisposing syndrome	Enrichment	SMAD4	0.59

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Transcriptional regulation of brown and beige adipocyte differentiation

Pathway Network for Transcriptional regulation of brown and beige adipocyte differentiation

Member Pathways for Transcriptional regulation of brown and beige adipocyte differentiation

Pathways in the Transcriptional regulation of brown and beige adipocyte differentiation SuperPath

Associated Genes for Transcriptional regulation of brown and beige adipocyte differentiation

Associated Disorders for Transcriptional regulation of brown and beige adipocyte differentiation

Disorders associated with Transcriptional regulation of brown and beige adipocyte differentiation SuperPath

STRING Interaction Network for Transcriptional regulation of brown and beige adipocyte differentiation

Sources for Transcriptional regulation of brown and beige adipocyte differentiation