Transcriptional regulation of white adipocyte differentiation

Pathway network for the Transcriptional regulation of white adipocyte differentiation SuperPath

Sources:

Reactome

Pathways in the Transcriptional regulation of white adipocyte differentiation SuperPath

#	Name	Source	Genes
1	Transcriptional regulation of white adipocyte differentiation	Reactome	ADIPOQ ADIRF ANGPTL4 CARM1 CCNC CCND3 CD36 CDK19 CDK4 CDK8 CEBPA CEBPB CEBPD CHD9 CREBBP EBF1 EGR2 EP300 FABP4 FAM120B HDAC3 HELZ2 KLF4 KLF5 LEP LPL MED1 MED10 MED11 MED12 MED13 MED13L MED14 MED15 MED16 MED17 MED18 MED19 MED20 MED21 MED22 MED23 MED24 MED25 MED26 MED27 MED28 MED29 MED30 MED31 MED4 MED6 MED7 MED8 MED9 NCOA1 NCOA2 NCOA3 NCOA6 NCOR1 NCOR2 NFKB1 NR2F2 PCK1 PLIN1 PPARA PPARG PPARGC1A RELA RXRA SLC2A4 SMARCD3 SREBF1 SREBF2 TBL1X TBL1XR1 TGFB1 TGS1 THRAP3 WNT1 WNT10B ZNF467 ZNF638 (see all 83) (see less)
2	Regulation of lipid metabolism by PPARalpha	Reactome	ABCA1 ABCB4 ACADM ACOX1 ACSL1 AGT AHR AHRR ALAS1 ANGPTL4 ANKRD1 APOA1 APOA2 APOA5 ARNT ARNT2 BMAL1 CARM1 CCNC CD36 CDK19 CDK8 CHD9 CLOCK CPT1A CPT2 CREBBP CYP1A1 CYP4A11 CYP7A1 EP300 ESRRA FABP1 FADS1 FAM120B FDFT1 FHL2 G0S2 GLIPR1 GPS2 GRHL1 HDAC3 HELZ2 HMGCR HMGCS1 HMGCS2 ME1 MED1 MED10 MED11 MED12 MED13 MED13L MED14 MED15 MED16 MED17 MED18 MED19 MED20 MED21 MED22 MED23 MED24 MED25 MED26 MED27 MED28 MED29 MED30 MED31 MED4 MED6 MED7 MED8 MED9 MTF1 NCOA1 NCOA2 NCOA3 NCOA6 NCOR1 NCOR2 NFYA NFYB NFYC NPAS2 NR1D1 NR1H2 NR1H3 NR1H4 NRF1 PEX11A PLIN2 PPARA PPARG PPARGC1A PPARGC1B RGL1 RORA RXRA RXRB SIN3A SIN3B SLC27A1 SMARCD3 SP1 SREBF1 SREBF2 SULT2A1 TBL1X TBL1XR1 TGS1 THRAP3 TIAM2 TNFRSF21 TRIB3 TXNRD1 UGT1A9 (see all 119) (see less)
3	PPARA activates gene expression	Reactome	ABCA1 ABCB4 ACADM ACOX1 ACSL1 AGT AHR AHRR ALAS1 ANGPTL4 ANKRD1 APOA1 APOA2 APOA5 ARNT ARNT2 BMAL1 CARM1 CCNC CD36 CDK19 CDK8 CHD9 CLOCK CPT1A CPT2 CREBBP CYP1A1 CYP4A11 CYP7A1 EP300 ESRRA FABP1 FADS1 FAM120B FDFT1 FHL2 G0S2 GLIPR1 GPS2 GRHL1 HDAC3 HELZ2 HMGCR HMGCS1 HMGCS2 ME1 MED1 MED10 MED11 MED12 MED13 MED13L MED14 MED15 MED16 MED17 MED18 MED19 MED20 MED21 MED22 MED23 MED24 MED25 MED26 MED27 MED28 MED29 MED30 MED31 MED4 MED6 MED7 MED8 MED9 MTF1 NCOA1 NCOA2 NCOA3 NCOA6 NCOR1 NCOR2 NFYA NFYB NFYC NPAS2 NR1D1 NR1H2 NR1H3 NR1H4 NRF1 PEX11A PLIN2 PPARA PPARG PPARGC1A PPARGC1B RGL1 RORA RXRA RXRB SLC27A1 SMARCD3 SP1 SREBF1 SREBF2 SULT2A1 TBL1X TBL1XR1 TGS1 THRAP3 TIAM2 TNFRSF21 TRIB3 TXNRD1 UGT1A9 (see all 117) (see less)
4	Adipogenesis	Reactome	ADIPOQ ADIRF ANGPTL4 BMP7 CARM1 CCNC CCND3 CD36 CDK19 CDK4 CDK8 CEBPA CEBPB CEBPD CHD3 CHD4 CHD9 CIDEA COX7A1 CREBBP DIO2 EBF1 EBF2 EGR2 ELOVL3 EP300 FABP4 FAM120B GATAD2A GATAD2B HDAC1 HDAC2 HDAC3 HELZ2 HNRNPU KLF4 KLF5 LEP LPL MBD3 MED1 MED10 MED11 MED12 MED13 MED13L MED14 MED15 MED16 MED17 MED18 MED19 MED20 MED21 MED22 MED23 MED24 MED25 MED26 MED27 MED28 MED29 MED30 MED31 MED4 MED6 MED7 MED8 MED9 MTA1 MTA2 MTA3 NCOA1 NCOA2 NCOA3 NCOA6 NCOR1 NCOR2 NFKB1 NR2F2 PCK1 PLIN1 PPARA PPARG PPARGC1A PPARGC1B PRDM16 RBBP4 RBBP7 RELA RXRA SLC2A4 SMAD1 SMAD4 SMARCD3 SREBF1 SREBF2 TBL1X TBL1XR1 TGFB1 TGS1 THRAP3 UCP1 WNT1 WNT10B ZNF423 ZNF467 ZNF638 (see all 108) (see less)

Gene overlap in member pathways for Transcriptional regulation of white adipocyte differentiation SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	MED6	Mediator Complex Subunit 6	Protein Coding	4
2	MED16	Mediator Complex Subunit 16	Protein Coding	4
3	CDK8	Cyclin Dependent Kinase 8	Protein Coding	4
4	CARM1	Coactivator Associated Arginine Methyltransferase 1	Protein Coding	4
5	NCOA2	Nuclear Receptor Coactivator 2	Protein Coding	4
6	PPARGC1A	PPARG Coactivator 1 Alpha	Protein Coding	4
7	MED8	Mediator Complex Subunit 8	Protein Coding	4
8	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	4
9	EP300	EP300 Lysine Acetyltransferase	Protein Coding	4
10	MED19	Mediator Complex Subunit 19	Protein Coding	4
11	NCOA6	Nuclear Receptor Coactivator 6	Protein Coding	4
12	CDK19	Cyclin Dependent Kinase 19	Protein Coding	4
13	MED13L	Mediator Complex Subunit 13L	Protein Coding	4
14	MED4	Mediator Complex Subunit 4	Protein Coding	4
15	MED11	Mediator Complex Subunit 11	Protein Coding	4
16	MED31	Mediator Complex Subunit 31	Protein Coding	4
17	ANGPTL4	Angiopoietin Like 4	Protein Coding	4
18	MED15	Mediator Complex Subunit 15	Protein Coding	4
19	PPARA	Peroxisome Proliferator Activated Receptor Alpha	Protein Coding	4
20	PPARG	Peroxisome Proliferator Activated Receptor Gamma	Protein Coding	4
21	MED1	Mediator Complex Subunit 1	Protein Coding	4
22	MED18	Mediator Complex Subunit 18	Protein Coding	4
23	MED9	Mediator Complex Subunit 9	Protein Coding	4
24	MED29	Mediator Complex Subunit 29	Protein Coding	4
25	RXRA	Retinoid X Receptor Alpha	Protein Coding	4
26	SMARCD3	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit D3	Protein Coding	4
27	SREBF1	Sterol Regulatory Element Binding Transcription Factor 1	Protein Coding	4
28	SREBF2	Sterol Regulatory Element Binding Transcription Factor 2	Protein Coding	4
29	MED22	Mediator Complex Subunit 22	Protein Coding	4
30	TBL1X	Transducin Beta Like 1 X-Linked	Protein Coding	4
31	TBL1XR1	TBL1X/Y Related 1	Protein Coding	4
32	CHD9	Chromodomain Helicase DNA Binding Protein 9	Protein Coding	4
33	MED28	Mediator Complex Subunit 28	Protein Coding	4
34	MED25	Mediator Complex Subunit 25	Protein Coding	4
35	NCOA3	Nuclear Receptor Coactivator 3	Protein Coding	4
36	MED10	Mediator Complex Subunit 10	Protein Coding	4
37	FAM120B	Family With Sequence Similarity 120 Member B	Protein Coding	4
38	HELZ2	Helicase With Zinc Finger 2	Protein Coding	4
39	NCOA1	Nuclear Receptor Coactivator 1	Protein Coding	4
40	HDAC3	Histone Deacetylase 3	Protein Coding	4
41	CCNC	Cyclin C	Protein Coding	4
42	MED30	Mediator Complex Subunit 30	Protein Coding	4
43	MED14	Mediator Complex Subunit 14	Protein Coding	4
44	MED21	Mediator Complex Subunit 21	Protein Coding	4
45	MED23	Mediator Complex Subunit 23	Protein Coding	4
46	MED17	Mediator Complex Subunit 17	Protein Coding	4
47	MED26	Mediator Complex Subunit 26	Protein Coding	4
48	MED27	Mediator Complex Subunit 27	Protein Coding	4
49	MED7	Mediator Complex Subunit 7	Protein Coding	4
50	MED20	Mediator Complex Subunit 20	Protein Coding	4
51	CD36	CD36 Molecule (CD36 Blood Group)	Protein Coding	4
52	NCOR1	Nuclear Receptor Corepressor 1	Protein Coding	4
53	NCOR2	Nuclear Receptor Corepressor 2	Protein Coding	4
54	TGS1	Trimethylguanosine Synthase 1	Protein Coding	4
55	MED24	Mediator Complex Subunit 24	Protein Coding	4
56	THRAP3	Thyroid Hormone Receptor Associated Protein 3	Protein Coding	4
57	MED12	Mediator Complex Subunit 12	Protein Coding	4
58	MED13	Mediator Complex Subunit 13	Protein Coding	4
59	PPARGC1B	PPARG Coactivator 1 Beta	Protein Coding	3
60	CDK4	Cyclin Dependent Kinase 4	Protein Coding	2
61	CEBPA	CCAAT Enhancer Binding Protein Alpha	Protein Coding	2
62	CEBPB	CCAAT Enhancer Binding Protein Beta	Protein Coding	2
63	CEBPD	CCAAT Enhancer Binding Protein Delta	Protein Coding	2
64	ADIRF	Adipogenesis Regulatory Factor	Protein Coding	2
65	ZNF467	Zinc Finger Protein 467	Protein Coding	2
66	EBF1	EBF Transcription Factor 1	Protein Coding	2
67	EGR2	Early Growth Response 2	Protein Coding	2
68	FABP4	Fatty Acid Binding Protein 4	Protein Coding	2
69	ZNF638	Zinc Finger Protein 638	Protein Coding	2
70	LEP	Leptin	Protein Coding	2
71	LPL	Lipoprotein Lipase	Protein Coding	2
72	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	2
73	PCK1	Phosphoenolpyruvate Carboxykinase 1	Protein Coding	2
74	PLIN1	Perilipin 1	Protein Coding	2
75	RELA	RELA Proto-Oncogene, NF-KB Subunit	Protein Coding	2
76	SLC2A4	Solute Carrier Family 2 Member 4	Protein Coding	2
77	KLF5	KLF Transcription Factor 5	Protein Coding	2
78	NR2F2	Nuclear Receptor Subfamily 2 Group F Member 2	Protein Coding	2
79	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	2
80	WNT1	Wnt Family Member 1	Protein Coding	2
81	WNT10B	Wnt Family Member 10B	Protein Coding	2
82	CCND3	Cyclin D3	Protein Coding	2
83	KLF4	KLF Transcription Factor 4	Protein Coding	2
84	ADIPOQ	Adiponectin, C1Q And Collagen Domain Containing	Protein Coding	2
85	NR1H3	Nuclear Receptor Subfamily 1 Group H Member 3	Protein Coding	2
86	GLIPR1	GLI Pathogenesis Related 1	Protein Coding	2
87	APOA5	Apolipoprotein A5	Protein Coding	2
88	PLIN2	Perilipin 2	Protein Coding	2
89	CPT1A	Carnitine Palmitoyltransferase 1A	Protein Coding	2
90	CPT2	Carnitine Palmitoyltransferase 2	Protein Coding	2
91	CYP1A1	Cytochrome P450 Family 1 Subfamily A Member 1	Protein Coding	2
92	CYP4A11	Cytochrome P450 Family 4 Subfamily A Member 11	Protein Coding	2
93	CYP7A1	Cytochrome P450 Family 7 Subfamily A Member 1	Protein Coding	2
94	AGT	Angiotensinogen	Protein Coding	2
95	ABCA1	ATP Binding Cassette Subfamily A Member 1	Protein Coding	2
96	AHR	Aryl Hydrocarbon Receptor	Protein Coding	2
97	ESRRA	Estrogen Related Receptor Alpha	Protein Coding	2
98	ALAS1	5''-Aminolevulinate Synthase 1	Protein Coding	2
99	FABP1	Fatty Acid Binding Protein 1	Protein Coding	2
100	ACSL1	Acyl-CoA Synthetase Long Chain Family Member 1	Protein Coding	2
101	FDFT1	Farnesyl-Diphosphate Farnesyltransferase 1	Protein Coding	2
102	FHL2	Four And A Half LIM Domains 2	Protein Coding	2
103	RGL1	Ral Guanine Nucleotide Dissociation Stimulator Like 1	Protein Coding	2
104	TIAM2	TIAM Rac1 Associated GEF 2	Protein Coding	2
105	ANKRD1	Ankyrin Repeat Domain 1	Protein Coding	2
106	TNFRSF21	TNF Receptor Superfamily Member 21	Protein Coding	2
107	GPS2	G Protein Pathway Suppressor 2	Protein Coding	2
108	GRHL1	Grainyhead Like Transcription Factor 1	Protein Coding	2
109	HMGCR	3-Hydroxy-3-Methylglutaryl-CoA Reductase	Protein Coding	2
110	HMGCS1	3-Hydroxy-3-Methylglutaryl-CoA Synthase 1	Protein Coding	2
111	HMGCS2	3-Hydroxy-3-Methylglutaryl-CoA Synthase 2	Protein Coding	2
112	APOA1	Apolipoprotein A1	Protein Coding	2
113	APOA2	Apolipoprotein A2	Protein Coding	2
114	ACADM	Acyl-CoA Dehydrogenase Medium Chain	Protein Coding	2
115	SLC27A1	Solute Carrier Family 27 Member 1	Protein Coding	2
116	FADS1	Fatty Acid Desaturase 1	Protein Coding	2
117	ARNT	Aryl Hydrocarbon Receptor Nuclear Translocator	Protein Coding	2
118	BMAL1	Basic Helix-Loop-Helix ARNT Like 1	Protein Coding	2
119	ME1	Malic Enzyme 1	Protein Coding	2
120	MTF1	Metal Regulatory Transcription Factor 1	Protein Coding	2
121	NFYA	Nuclear Transcription Factor Y Subunit Alpha	Protein Coding	2
122	NFYB	Nuclear Transcription Factor Y Subunit Beta	Protein Coding	2
123	NFYC	Nuclear Transcription Factor Y Subunit Gamma	Protein Coding	2
124	NPAS2	Neuronal PAS Domain Protein 2	Protein Coding	2
125	NRF1	Nuclear Respiratory Factor 1	Protein Coding	2
126	G0S2	G0/G1 Switch 2	Protein Coding	2
127	ACOX1	Acyl-CoA Oxidase 1	Protein Coding	2
128	ABCB4	ATP Binding Cassette Subfamily B Member 4	Protein Coding	2
129	UGT1A9	UDP Glucuronosyltransferase Family 1 Member A9	Protein Coding	2
130	AHRR	Aryl Hydrocarbon Receptor Repressor	Protein Coding	2
131	TRIB3	Tribbles Pseudokinase 3	Protein Coding	2
132	RORA	RAR Related Orphan Receptor A	Protein Coding	2
133	RXRB	Retinoid X Receptor Beta	Protein Coding	2
134	SP1	Sp1 Transcription Factor	Protein Coding	2
135	SULT2A1	Sulfotransferase Family 2A Member 1	Protein Coding	2
136	TXNRD1	Thioredoxin Reductase 1	Protein Coding	2
137	NR1H2	Nuclear Receptor Subfamily 1 Group H Member 2	Protein Coding	2
138	PEX11A	Peroxisomal Biogenesis Factor 11 Alpha	Protein Coding	2
139	NR1D1	Nuclear Receptor Subfamily 1 Group D Member 1	Protein Coding	2
140	CLOCK	Clock Circadian Regulator	Protein Coding	2
141	ARNT2	Aryl Hydrocarbon Receptor Nuclear Translocator 2	Protein Coding	2
142	NR1H4	Nuclear Receptor Subfamily 1 Group H Member 4	Protein Coding	2
143	SIN3B	SIN3 Transcription Regulator Family Member B	Protein Coding	1
144	SIN3A	SIN3 Transcription Regulator Family Member A	Protein Coding	1
145	CHD3	Chromodomain Helicase DNA Binding Protein 3	Protein Coding	1
146	CHD4	Chromodomain Helicase DNA Binding Protein 4	Protein Coding	1
147	CIDEA	Cell Death Inducing DFFA Like Effector A	Protein Coding	1
148	COX7A1	Cytochrome C Oxidase Subunit 7A1	Protein Coding	1
149	DIO2	Iodothyronine Deiodinase 2	Protein Coding	1
150	ZNF423	Zinc Finger Protein 423	Protein Coding	1
151	HDAC1	Histone Deacetylase 1	Protein Coding	1
152	HDAC2	Histone Deacetylase 2	Protein Coding	1
153	HNRNPU	Heterogeneous Nuclear Ribonucleoprotein U	Protein Coding	1
154	SMAD1	SMAD Family Member 1	Protein Coding	1
155	SMAD4	SMAD Family Member 4	Protein Coding	1
156	MBD3	Methyl-CpG Binding Domain Protein 3	Protein Coding	1
157	GATAD2A	GATA Zinc Finger Domain Containing 2A	Protein Coding	1
158	GATAD2B	GATA Zinc Finger Domain Containing 2B	Protein Coding	1
159	MTA3	Metastasis Associated 1 Family Member 3	Protein Coding	1
160	RBBP4	RB Binding Protein 4, Chromatin Remodeling Factor	Protein Coding	1
161	RBBP7	RB Binding Protein 7, Chromatin Remodeling Factor	Protein Coding	1
162	PRDM16	PR/SET Domain 16	Protein Coding	1
163	EBF2	EBF Transcription Factor 2	Protein Coding	1
164	BMP7	Bone Morphogenetic Protein 7	Protein Coding	1
165	UCP1	Uncoupling Protein 1	Protein Coding	1
166	ELOVL3	ELOVL Fatty Acid Elongase 3	Protein Coding	1
167	MTA1	Metastasis Associated 1	Protein Coding	1
168	MTA2	Metastasis Associated 1 Family Member 2	Protein Coding	1

Disorders associated with Transcriptional regulation of white adipocyte differentiation SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Witteveen-kolk syndrome	Enrichment	SIN3A, SIN3B	4.12
2	Hypoalphalipoproteinemia, primary, 2	Enrichment	ABCA1, APOA1	3.66
3	Leptin deficiency or dysfunction	Enrichment	LEP, PPARG	3.66
4	Hypoalphalipoproteinemia, primary, 1	Enrichment	ABCA1, APOA1	3.36
5	Intrahepatic cholestasis of pregnancy	Enrichment	ABCB4, NR1H4	3.36
6	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	3.26
7	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	3.26
8	Congenital heart defects, multiple types, 4	Enrichment	BMP7, NR2F2	3.21
9	Cholestasis, progressive familial intrahepatic, 1	Enrichment	ABCB4, NR1H4	2.97
10	Heart disease	Enrichment	CREBBP, NR2F2	2.49
11	Corpus callosum, agenesis of	Enrichment	CREBBP, MED12	2.43
12	Isolated corpus callosum agenesis	Enrichment	CREBBP, MED12	2.43
13	Rare genetic intellectual disability	Enrichment	CREBBP, EP300	2.43
14	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP, MED12	2.43
15	Hydrocephalus, congenital, 1	Enrichment	CDK8, MED12	2.38
16	Myeloma, multiple	Enrichment	CREBBP, NCOR2, RXRA	2.31
17	Diffuse large b-cell lymphoma	Enrichment	CREBBP, TBL1XR1	2.23
18	Phosphoenolpyruvate carboxykinase deficiency, cytosolic	Enrichment	PCK1	2.21
19	Hypothyroidism, congenital, nongoitrous, 8	Enrichment	TBL1X	2.21
20	Charcot-marie-tooth disease, demyelinating, type 1d	Enrichment	EGR2	2.21
21	Coronary heart disease 7	Enrichment	CD36	2.21
22	Melanoma, cutaneous malignant 3	Enrichment	CDK4	2.21
23	Intellectual developmental disorder, autosomal recessive 18, with or without epilepsy	Enrichment	MED23	2.21
24	Mucoepithelial dysplasia, hereditary	Enrichment	SREBF1	2.21
25	Split-hand/foot malformation 6	Enrichment	WNT10B	2.21
26	Tooth agenesis, selective, 8	Enrichment	WNT10B	2.21
27	Neurodevelopmental disorder with spasticity, cataracts, and cerebellar hypoplasia	Enrichment	MED27	2.21
28	Impaired intellectual development and distinctive facial features with or without cardiac defects	Enrichment	MED13L	2.21
29	46,xx sex reversal 5	Enrichment	NR2F2	2.21
30	Ifap syndrome 2	Enrichment	SREBF1	2.21
31	Bone mineral density quantitative trait locus 16	Enrichment	WNT1	2.21
32	Platelet glycoprotein iv deficiency	Enrichment	CD36	2.21
33	Plasma triglyceride level quantitative trait locus	Enrichment	ANGPTL4	2.21
34	Basel-vanagaite-smirin-yosef syndrome	Enrichment	MED25	2.21
35	Neurodegeneration with developmental delay, early respiratory failure, myoclonic seizures, and brain abnormalities	Enrichment	MED11	2.21
36	Menke-hennekam syndrome 1	Enrichment	CREBBP	2.21
37	Guillouet-gordon syndrome	Enrichment	MED16	2.21
38	Pparg-associated congenital generalized lipodystrophy	Enrichment	PPARG	2.21
39	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	2.21
40	Charcot-marie-tooth disease type 1d	Enrichment	EGR2	2.21
41	Acute myeloid leukemia with mutated cebpa	Enrichment	CEBPA	2.21
42	Menke-hennekam syndrome	Enrichment	CREBBP	2.21
43	Spermatogenic failure, x-linked, 9	Enrichment	RBBP7	2.10
44	Gand syndrome	Enrichment	GATAD2B	2.10
45	Developmental and epileptic encephalopathy 54	Enrichment	HNRNPU	2.10
46	Left ventricular noncompaction 8	Enrichment	PRDM16	2.10
47	Nephronophthisis 14	Enrichment	ZNF423	2.10
48	Severe intellectual disability-poor language-strabismus-grimacing face-long fingers syndrome	Enrichment	GATAD2B	2.10
49	Heritable thoracic aortic disease	Enrichment	SMAD4	2.10
50	1q44 microdeletion syndrome	Enrichment	HNRNPU	2.10
51	Acyl-coa dehydrogenase, medium-chain, deficiency of	Enrichment	ACADM	2.06
52	Retinitis pigmentosa 85	Enrichment	AHR	2.06
53	Gallbladder disease 1	Enrichment	ABCB4	2.06
54	Peroxisomal acyl-coa oxidase deficiency	Enrichment	ACOX1	2.06
55	Mitchell syndrome	Enrichment	ACOX1	2.06
56	Foveal hypoplasia 3	Enrichment	AHR	2.06
57	Familial apolipoprotein a5 deficiency	Enrichment	APOA5	2.06
58	Webb-dattani syndrome	Enrichment	ARNT2	2.06
59	Cholestasis, progressive familial intrahepatic, 5	Enrichment	NR1H4	2.06
60	Hypercholesterolemia due to cholesterol 7alpha-hydroxylase deficiency	Enrichment	CYP7A1	2.06
61	Low density lipoprotein cholesterol level quantitative trait locus 3	Enrichment	HMGCR	2.06
62	Muscular dystrophy, limb-girdle, autosomal recessive 28	Enrichment	HMGCR	2.06
63	Medium-chain acyl-coenzyme a dehydrogenase deficiency	Enrichment	ACADM	2.06
64	Aapoaii amyloidosis	Enrichment	APOA2	2.06
65	Hypoalphalipoproteinemia	Enrichment	ABCA1	2.06
66	Chromosome 15q24 deletion syndrome	Enrichment	SIN3A	2.06
67	Scoliosis	Enrichment	CREBBP, MED13L	2.03
68	Camurati-engelmann disease 1	Enrichment	TGFB1	1.91
69	Hyperlipoproteinemia, type i	Enrichment	LPL	1.91
70	Argininemia	Enrichment	MED23	1.91
71	Thumb deformity	Enrichment	CREBBP	1.91
72	Ebstein anomaly	Enrichment	CDK8	1.91
73	Carotid intimal medial thickness 1	Enrichment	PPARG	1.91
74	Hardikar syndrome	Enrichment	MED12	1.91
75	Opitz-kaveggia syndrome	Enrichment	MED12	1.91
76	Neuropathy, congenital hypomyelinating, 1, autosomal recessive	Enrichment	EGR2	1.91
77	Osteogenesis imperfecta, type xv	Enrichment	WNT1	1.91
78	Lipase deficiency, combined	Enrichment	LPL	1.91
79	Charcot-marie-tooth disease, axonal, type 2b2	Enrichment	MED25	1.91
80	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	1.91
81	Cardiomyopathy, dilated, 1ff	Enrichment	KLF5	1.91
82	Developmental and epileptic encephalopathy 87	Enrichment	CDK19	1.91
83	Autoinflammatory disease, familial, behcet-like 3	Enrichment	RELA	1.91
84	Ohdo syndrome, x-linked	Enrichment	MED12	1.91
85	Menke-hennekam syndrome 2	Enrichment	EP300	1.91
86	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.91
87	Rela fusion-positive ependymoma	Enrichment	RELA	1.91
88	Charcot-marie-tooth disease type 2b2	Enrichment	MED25	1.91
89	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	1.91
90	Camurati-engelmann disease	Enrichment	TGFB1	1.91
91	Familial lipoprotein lipase deficiency	Enrichment	LPL	1.91
92	Cholestasis-pigmentary retinopathy-cleft palate syndrome	Enrichment	MED12	1.91
93	Intellectual developmental disorder with hypotonia and behavioral abnormalities	Enrichment	CDK8	1.91
94	Med12-related disorders	Enrichment	MED12	1.91
95	Familial partial lipodystrophy	Enrichment	PPARG	1.91
96	Blepharophimosis - intellectual disability syndrome, mkb type	Enrichment	MED12	1.91
97	Common variable immunodeficiency 12	Enrichment	NFKB1	1.91
98	Myhre syndrome	Enrichment	SMAD4	1.80
99	Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome	Enrichment	SMAD4	1.80
100	Sifrim-hitz-weiss syndrome	Enrichment	CHD4	1.80
101	Snijders blok-campeau syndrome	Enrichment	CHD3	1.80
102	Hyperlipoproteinemia, type v	Enrichment	APOA5	1.77
103	Tangier disease	Enrichment	ABCA1	1.77
104	Carnitine palmitoyltransferase ii deficiency, infantile	Enrichment	CPT2	1.77
105	Cholestasis, progressive familial intrahepatic, 3	Enrichment	ABCB4	1.77
106	Carnitine palmitoyltransferase ii deficiency, lethal neonatal	Enrichment	CPT2	1.77
107	Carnitine palmitoyltransferase i deficiency	Enrichment	CPT1A	1.77
108	Carnitine palmitoyltransferase ii deficiency, myopathic, stress-induced	Enrichment	CPT2	1.77
109	Hypothyroidism, congenital, nongoitrous, 6	Enrichment	NR1D1	1.77
110	Encephalopathy, acute, infection-induced 4	Enrichment	CPT2	1.77
111	Cholestasis, intrahepatic, of pregnancy 3	Enrichment	ABCB4	1.77
112	3-hydroxy-3-methylglutaryl-coa synthase-2 deficiency	Enrichment	HMGCS2	1.77
113	Squalene synthase deficiency	Enrichment	FDFT1	1.77
114	Intellectual developmental disorder with or without epilepsy or cerebellar ataxia	Enrichment	RORA	1.77
115	Hypoalphalipoproteinemia, primary, 2, intermediate	Enrichment	APOA1	1.77
116	Intrahepatic cholestasis	Enrichment	ABCB4	1.77
117	Amyloidosis, hereditary systemic 3	Enrichment	APOA1	1.77
118	Acute necrotizing encephalopathy of childhood	Enrichment	CPT2	1.77
119	Intellectual developmental disorder, x-linked, syndromic, lujan-fryns type	Enrichment	MED12	1.74
120	Ifap syndrome 1, with or without bresheck syndrome	Enrichment	SREBF1	1.74
121	Pierpont syndrome	Enrichment	TBL1XR1	1.74
122	Osteoporosis, juvenile	Enrichment	WNT1	1.74
123	Transposition of the great arteries, dextro-looped	Enrichment	MED13L	1.74
124	Adiponectin deficiency	Enrichment	ADIPOQ	1.74
125	Microcephaly, postnatal progressive, with seizures and brain atrophy	Enrichment	MED17	1.74
126	Lipodystrophy, familial partial, type 4	Enrichment	PLIN1	1.74
127	Anus, imperforate	Enrichment	MED12	1.74
128	Intellectual developmental disorder, autosomal dominant 61	Enrichment	MED13	1.74
129	Tethered spinal cord syndrome	Enrichment	CREBBP	1.74
130	Dedifferentiated liposarcoma	Enrichment	CDK4	1.74
131	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.74
132	Intellectual developmental disorder, autosomal dominant 41	Enrichment	TBL1XR1	1.74
133	Charcot-marie-tooth disease type 1	Enrichment	EGR2	1.74
134	Phosphoenolpyruvate carboxykinase deficiency	Enrichment	PCK1	1.74
135	Well-differentiated liposarcoma	Enrichment	CDK4	1.74
136	Complex neurodevelopmental disorder	Enrichment	CDK8, MED13, MED27, RORA	1.65
137	Juvenile polyposis syndrome	Enrichment	SMAD4	1.63
138	Isolated growth hormone deficiency, type ii	Enrichment	MED13	1.62
139	Lipodystrophy, familial partial, type 3	Enrichment	PPARG	1.62
140	Congenital generalized lipodystrophy	Enrichment	PPARG	1.62
141	Blood platelet disease	Enrichment	CD36	1.62
142	Coronary artery anomaly	Enrichment	LPL	1.62
143	Cerebral malaria	Enrichment	CD36	1.62
144	Isolated congenitally uncorrected transposition of the great arteries	Enrichment	MED13L	1.62
145	Spastic paraplegia 50, autosomal recessive	Enrichment	APOA1	1.59
146	Type 2 diabetes mellitus	Enrichment	PPARG, SLC2A4	1.57
147	Hypertrophic neuropathy of dejerine-sottas	Enrichment	EGR2	1.52
148	Hyperlipidemia, familial combined, 3	Enrichment	LPL	1.52
149	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.52
150	Inherited acute myeloid leukemia	Enrichment	CEBPA	1.52
151	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	CEBPA	1.52
152	Colorectal cancer	Enrichment	EP300, PPARG, SMAD4	1.49
153	Hypertriglyceridemia 1	Enrichment	APOA5	1.47
154	Hydrocephalus, congenital, 2, with or without brain or eye anomalies	Enrichment	ACADM	1.47
155	Pierre robin syndrome	Enrichment	MED13L	1.44
156	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	1.44
157	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	1.44
158	Hypertrichosis	Enrichment	CREBBP	1.44
159	46,xy disorder of sex development	Enrichment	NR2F2	1.44
160	Ventricular septal defect 1	Enrichment	BMP7	1.41
161	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	SMAD4	1.41
162	Common variable immunodeficiency	Enrichment	NFKB1	1.38
163	Vesicoureteral reflux	Enrichment	MED13L	1.38
164	Amyloidosis, hereditary systemic 2	Enrichment	APOA1	1.37
165	Congenital myopathy 3 with rigid spine	Enrichment	HMGCS1	1.37
166	Gastric cancer	Enrichment	CDK4, SMAD4	1.34
167	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	MED12, SMAD4	1.32
168	Isolated split hand-split foot malformation	Enrichment	WNT10B	1.32
169	Autosomal recessive non-syndromic intellectual disability	Enrichment	MED23, MED25	1.31
170	Renal tubular dysgenesis	Enrichment	AGT	1.30
171	Charge syndrome	Enrichment	EP300	1.27
172	Arima syndrome	Enrichment	ZNF423	1.26
173	Gallbladder cancer	Enrichment	SMAD4	1.26
174	Hereditary hemorrhagic telangiectasia	Enrichment	SMAD4	1.26
175	Progressive familial intrahepatic cholestasis	Enrichment	ABCB4	1.23
176	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.23
177	Infantile nephronophthisis	Enrichment	ZNF423	1.21
178	Coronary heart disease 5	Enrichment	ABCA1	1.12
179	Limb-girdle muscular dystrophy	Enrichment	HMGCR	1.12
180	Familial isolated dilated cardiomyopathy	Enrichment	ANKRD1, FHL2	1.12
181	Diaphragmatic hernia, congenital	Enrichment	CDK8	1.12
182	Osteogenesis imperfecta, type iv	Enrichment	WNT1	1.12
183	Acute promyelocytic leukemia	Enrichment	TBL1XR1	1.12
184	Osteoporosis	Enrichment	WNT1	1.08
185	Crigler-najjar syndrome, type i	Enrichment	UGT1A9	1.08
186	Hyperbilirubinemia, transient familial neonatal	Enrichment	UGT1A9	1.08
187	Bilirubin, serum level of, quantitative trait locus 1	Enrichment	UGT1A9	1.08
188	Crigler-najjar syndrome, type ii	Enrichment	UGT1A9	1.08
189	Polydactyly, postaxial, type a1	Enrichment	EP300	1.06
190	Osteogenesis imperfecta, type iii	Enrichment	WNT1	1.06
191	Inherited cancer-predisposing syndrome	Enrichment	CDK4, CEBPA, SMAD4	1.05
192	Gilbert syndrome	Enrichment	UGT1A9	1.04
193	Bilirubin metabolic disorder	Enrichment	UGT1A9	1.04
194	Gliosarcoma	Enrichment	PPARG	1.03
195	Chromosome 1p36 deletion syndrome	Enrichment	PRDM16	1.01
196	Septooptic dysplasia	Enrichment	ARNT2	1.01
197	Melanoma, cutaneous malignant 1	Enrichment	CDK4	1.00
198	Cardiomyopathy, dilated, 1e	Enrichment	MED12	1.00
199	Syndromic intellectual disability	Enrichment	MED16	1.00
200	Giant cell glioblastoma	Enrichment	PPARG	1.00
201	Heart, malformation of	Enrichment	CDK8	0.98
202	Charcot-marie-tooth disease type 4	Enrichment	EGR2	0.98
203	Hypercholesterolemia, familial, 1	Enrichment	APOA2	0.97
204	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	MED25	0.96
205	Multiple sclerosis	Enrichment	NR1H3	0.94
206	Cardiomyopathy, dilated, 1a	Enrichment	LPL	0.92
207	Familial hypercholesterolemia	Enrichment	APOA2	0.91
208	Tooth agenesis	Enrichment	WNT10B	0.90
209	Brittle bone disorder	Enrichment	WNT1	0.88
210	Malaria	Enrichment	CD36	0.88
211	Hypertension, essential	Enrichment	AGT	0.86
212	Strabismus	Enrichment	MED13L	0.82
213	Hirschsprung disease 1	Enrichment	SREBF1	0.79
214	Differentiated thyroid carcinoma	Enrichment	PPARG	0.79
215	Microcephaly	Enrichment	EP300, MED12	0.76
216	Cystic fibrosis	Enrichment	TGFB1	0.75
217	Pancreatic cancer	Enrichment	SMAD4	0.74
218	Non-syndromic x-linked intellectual disability	Enrichment	MED12	0.70
219	Leukemia, acute myeloid	Enrichment	CEBPA	0.66
220	Congenital nervous system abnormality	Enrichment	CPT2, CREBBP	0.63
221	Nervous system disease	Enrichment	CPT2, CREBBP	0.63
222	Left ventricular noncompaction	Enrichment	PRDM16	0.61
223	Body mass index quantitative trait locus 11	Enrichment	PPARG	0.58
224	Hypertelorism	Enrichment	MED13L	0.56
225	Undetermined early-onset epileptic encephalopathy	Enrichment	CDK19	0.54
226	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	PPARGC1A	0.52
227	Thrombocytopenia	Enrichment	SMAD4	0.50
228	Autism	Enrichment	CREBBP	0.45
229	Breast cancer	Enrichment	ABCA1	0.32
230	Autism spectrum disorder	Enrichment	MED13L	0.31
231	Retinitis pigmentosa	Enrichment	AHR	0.07

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Transcriptional regulation of white adipocyte differentiation

Pathway Network for Transcriptional regulation of white adipocyte differentiation

Pathway network for the Transcriptional regulation of white adipocyte differentiation SuperPath

Member Pathways for Transcriptional regulation of white adipocyte differentiation

Pathways in the Transcriptional regulation of white adipocyte differentiation SuperPath

Gene overlap in member pathways for Transcriptional regulation of white adipocyte differentiation SuperPath

Associated Genes for Transcriptional regulation of white adipocyte differentiation

Associated Disorders for Transcriptional regulation of white adipocyte differentiation

Disorders associated with Transcriptional regulation of white adipocyte differentiation SuperPath

STRING Interaction Network for Transcriptional regulation of white adipocyte differentiation

Sources for Transcriptional regulation of white adipocyte differentiation