Transport of the SLBP independent Mature mRNA

Pathway network for the Transport of the SLBP independent Mature mRNA SuperPath

Sources:

Reactome
PubChem

Pathways in the Transport of the SLBP independent Mature mRNA SuperPath

#	Name	Source	Genes
1	Transport of the SLBP independent Mature mRNA	Reactome	AAAS ALYREF EIF4E NCBP1 NCBP2 NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 NXF1 POM121 RAE1 RANBP2 SEC13 SEH1L TPR (see all 34) (see less)
2	SUMOylation	Reactome	AAAS AR AURKA AURKB BIRC5 BLM BMI1 BRCA1 CASP8AP2 CBX2 CBX4 CBX5 CBX8 CDCA8 CDKN2A CETN2 CHD3 COMMD3-BMI1 CREBBP CTBP1 DAXX DDX17 DDX5 DNMT1 DNMT3A DNMT3B EID3 EIF2AK2 EP300 ESR1 FOXL2 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HDAC1 HDAC2 HDAC4 HDAC7 HERC2 HIC1 HIPK2 HNRNPC HNRNPK IKBKE IKBKG INCENP ING2 L3MBTL2 MBD1 MDC1 MDM2 MITF MRTFA MTA1 NCOA1 NCOA2 NCOR2 NDC1 NFKB2 NFKBIA NOP58 NPM1 NR1H2 NR1H3 NR1H4 NR1I2 NR2C1 NR3C1 NR3C2 NR4A2 NR5A1 NR5A2 NRIP1 NSMCE1 NSMCE2 NSMCE3 NSMCE4A NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 PARK7 PARP1 PCGF2 PCNA PGR PHC1 PHC2 PHC3 PIAS1 PIAS2 PIAS3 PIAS4 PML POM121 PPARA PPARG PPARGC1A RAD21 RAD52 RAE1 RANBP2 RANGAP1 RARA RELA RING1 RNF168 RNF2 RORA RPA1 RWDD3 RXRA SAE1 SAFB SATB1 SATB2 SCMH1 SEC13 SEH1L SENP1 SENP2 SENP5 SIN3A SMC1A SMC3 SMC5 SMC6 SP100 SP3 STAG1 STAG2 SUMO1 SUMO2 SUMO3 SUZ12 TDG TFAP2A TFAP2B TFAP2C THRA THRB TOP1 TOP2A TOP2B TOPORS TP53 TP53BP1 TPR TRIM27 TRIM28 UBA2 UBE2I UHRF2 VDR VHL WRN XPC XRCC4 ZBED1 ZNF131 ZNF350 (see all 189) (see less)
3	SUMO E3 ligases SUMOylate target proteins	Reactome	AAAS AR AURKA AURKB BIRC5 BLM BMI1 BRCA1 CASP8AP2 CBX2 CBX4 CBX5 CBX8 CDCA8 CDKN2A CETN2 CHD3 COMMD3-BMI1 CREBBP CTBP1 DAXX DDX17 DDX5 DNMT1 DNMT3A DNMT3B EID3 EIF2AK2 EP300 ESR1 FOXL2 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HDAC1 HDAC2 HDAC4 HDAC7 HERC2 HIC1 HIPK2 HNRNPC HNRNPK IKBKE IKBKG INCENP ING2 L3MBTL2 MBD1 MDC1 MDM2 MITF MRTFA MTA1 NCOA1 NCOA2 NCOR2 NDC1 NFKB2 NFKBIA NOP58 NPM1 NR1H2 NR1H3 NR1H4 NR1I2 NR2C1 NR3C1 NR3C2 NR4A2 NR5A1 NR5A2 NRIP1 NSMCE1 NSMCE2 NSMCE3 NSMCE4A NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 PARK7 PARP1 PCGF2 PCNA PGR PHC1 PHC2 PHC3 PIAS1 PIAS2 PIAS3 PIAS4 PML POM121 PPARA PPARG PPARGC1A RAD21 RAD52 RAE1 RANBP2 RANGAP1 RARA RELA RING1 RNF168 RNF2 RORA RPA1 RXRA SAFB SATB1 SATB2 SCMH1 SEC13 SEH1L SIN3A SMC1A SMC3 SMC5 SMC6 SP100 SP3 STAG1 STAG2 SUMO1 SUMO2 SUMO3 SUZ12 TDG TFAP2A TFAP2B TFAP2C THRA THRB TOP1 TOP2A TOP2B TOPORS TP53 TP53BP1 TPR TRIM27 TRIM28 UBE2I UHRF2 VDR VHL WRN XPC XRCC4 ZBED1 ZNF131 ZNF350 (see all 183) (see less)
4	tRNA processing	Reactome	AAAS ADAT1 ADAT2 ADAT3 ALKBH8 C2orf49 CDKAL1 CLP1 CPSF1 CPSF4 CSTF2 CTU1 CTU2 DDX1 DUS2 ELAC2 EPRS1 FAM98B FTSJ1 GON7 GTPBP3 HSD17B10 LAGE3 LCMT2 METTL1 MTO1 NDC1 NSUN2 NSUN6 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 OSGEP OSGEPL1 POM121 POP1 POP4 POP5 POP7 PRORP PUS1 PUS3 PUS7 QNG1 QTRT1 QTRT2 RAE1 RAN RANBP2 RPP14 RPP21 RPP25 RPP30 RPP38 RPP40 RTCB RTRAF SEC13 SEH1L THADA THG1L TP53RK TPR TPRKB TRDMT1 TRIT1 TRMT1 TRMT10A TRMT10C TRMT11 TRMT112 TRMT13 TRMT44 TRMT5 TRMT6 TRMT61A TRMT61B TRMT9B TRMU TRNT1 TSEN15 TSEN2 TSEN34 TSEN54 TYW1 TYW2 TYW3 TYW5 URM1 WDR4 XPOT YRDC ZBTB8OS (see all 111) (see less)
5	SUMOylation of DNA damage response and repair proteins	Reactome	AAAS BLM BMI1 BRCA1 CBX2 CBX4 CBX8 CDKN2A CETN2 COMMD3-BMI1 EID3 HDAC7 HERC2 MDC1 NDC1 NSMCE1 NSMCE2 NSMCE3 NSMCE4A NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 PARP1 PCGF2 PHC1 PHC2 PHC3 PIAS1 PIAS2 PIAS4 PML POM121 RAD21 RAD52 RAE1 RANBP2 RING1 RNF168 RNF2 RPA1 SCMH1 SEC13 SEH1L SMC1A SMC3 SMC5 SMC6 SP100 STAG1 STAG2 SUMO1 SUMO2 SUMO3 TDG TPR UBE2I WRN XPC XRCC4 (see all 77) (see less)
6	ISG15 antiviral mechanism	Reactome	AAAS ARIH1 BECN1 EIF2AK2 EIF4A1 EIF4A2 EIF4A3 EIF4E EIF4E2 EIF4E3 EIF4G1 EIF4G2 EIF4G3 FLNB HERC5 IFIT1 IRF3 ISG15 JAK1 KPNA1 KPNA2 KPNA3 KPNA4 KPNA5 KPNA7 KPNB1 MAPK3 MX1 MX2 NDC1 NEDD4 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 PIN1 PLCG1 POM121 PPM1B RAE1 RANBP2 RIGI RPS27A SEC13 SEH1L STAT1 TPR TRIM25 UBA52 UBA7 UBB UBC UBE2E1 UBE2L6 UBE2N USP18 (see all 73) (see less)
7	SUMOylation of chromatin organization proteins	Reactome	AAAS BMI1 CBX2 CBX4 CBX5 CBX8 CHD3 COMMD3-BMI1 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HDAC1 HDAC2 HDAC4 L3MBTL2 NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 PCGF2 PHC1 PHC2 PHC3 PIAS1 PIAS2 POM121 RAE1 RANBP2 RING1 RNF2 SATB1 SATB2 SCMH1 SEC13 SEH1L SUMO1 SUMO2 SUMO3 SUZ12 TPR UBE2I ZBED1 (see all 71) (see less)
8	tRNA processing in the nucleus	Reactome	AAAS C2orf49 CLP1 CPSF1 CPSF4 CSTF2 DDX1 ELAC2 FAM98B NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POM121 POP1 POP4 POP5 POP7 RAE1 RAN RANBP2 RPP14 RPP21 RPP25 RPP30 RPP38 RPP40 RTCB RTRAF SEC13 SEH1L TPR TRNT1 TSEN15 TSEN2 TSEN34 TSEN54 XPOT ZBTB8OS (see all 57) (see less)
9	snRNP Assembly	Reactome	AAAS CLNS1A DDX20 GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GEMIN8 NCBP1 NCBP2 NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 PHAX POM121 PRMT5 RAE1 RANBP2 SEC13 SEH1L SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN TGS1 TPR WDR77 (see all 53) (see less)
10	Metabolism of non-coding RNA	Reactome	AAAS CLNS1A DDX20 GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GEMIN8 NCBP1 NCBP2 NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 PHAX POM121 PRMT5 RAE1 RANBP2 SEC13 SEH1L SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN TGS1 TPR WDR77 (see all 53) (see less)
11	Nuclear Envelope Breakdown	Reactome	AAAS BANF1 CCNB1 CCNB2 CDK1 CNEP1R1 CTDNEP1 EMD LEMD2 LEMD3 LMNA LMNB1 LPIN1 LPIN2 LPIN3 NDC1 NEK6 NEK7 NEK9 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 PLK1 POM121 PRKCA PRKCB RAE1 RANBP2 SEC13 SEH1L TMPO TPR VRK1 VRK2 (see all 52) (see less)
12	SUMOylation of RNA binding proteins	Reactome	AAAS BMI1 CBX2 CBX4 CBX8 COMMD3-BMI1 HNRNPC HNRNPK NDC1 NOP58 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 PCGF2 PHC1 PHC2 PHC3 POM121 RAE1 RANBP2 RING1 RNF2 SCMH1 SEC13 SEH1L SUMO1 SUMO2 TPR UBE2I (see all 47) (see less)
13	tRNA modification in the nucleus and cytosol	Reactome	ADAT1 ADAT2 ADAT3 ALKBH8 CDKAL1 CTU1 CTU2 DUS2 EPRS1 FTSJ1 GON7 LAGE3 LCMT2 METTL1 NSUN2 NSUN6 OSGEP PUS1 PUS3 PUS7 QNG1 QTRT1 QTRT2 THADA THG1L TP53RK TPRKB TRDMT1 TRIT1 TRMT1 TRMT10A TRMT11 TRMT112 TRMT13 TRMT44 TRMT5 TRMT6 TRMT61A TRMT9B TYW1 TYW2 TYW3 TYW5 URM1 WDR4 (see all 45) (see less)
14	SUMOylation of DNA replication proteins	Reactome	AAAS AURKA AURKB BIRC5 CDCA8 INCENP NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 PCNA PIAS3 PIAS4 POM121 RAE1 RANBP2 RANGAP1 SEC13 SEH1L SUMO1 SUMO2 SUMO3 TOP1 TOP2A TOP2B TPR UBE2I (see all 45) (see less)
15	Viral Messenger RNA Synthesis	Reactome	AAAS GTF2F1 GTF2F2 NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L POM121 RAE1 RANBP2 SEC13 SEH1L TPR (see all 43) (see less)
16	Transport of Mature mRNAs Derived from Intronless Transcripts	Reactome	AAAS ALYREF CPSF1 CPSF2 CPSF3 CPSF4 EIF4E FIP1L1 NCBP1 NCBP2 NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 NXF1 POM121 RAE1 RANBP2 SEC13 SEH1L SLBP SYMPK TPR WDR33 (see all 42) (see less)
17	Transport of Mature mRNA Derived from an Intronless Transcript	Reactome	AAAS ALYREF CPSF1 CPSF2 CPSF3 CPSF4 EIF4E FIP1L1 NCBP1 NCBP2 NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 NXF1 POM121 RAE1 RANBP2 SEC13 SEH1L SYMPK TPR WDR33 (see all 41) (see less)
18	NS1 Mediated Effects on Host Pathways	Reactome	AAAS CPSF4 EIF2AK2 ISG15 KPNA1 KPNA2 KPNA3 KPNA4 KPNA5 KPNA7 KPNB1 NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 PABPN1 POM121 RAE1 RANBP2 SEC13 SEH1L TPR (see all 40) (see less)
19	SUMOylation of ubiquitinylation proteins	Reactome	AAAS MDM2 NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 PIAS1 PIAS2 PIAS4 PML POM121 RAE1 RANBP2 SEC13 SEH1L SUMO1 TPR TRIM27 UBE2I VHL (see all 38) (see less)
20	Interactions of Rev with host cellular proteins	Reactome	AAAS KPNB1 NDC1 NPM1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POM121 RAE1 RAN RANBP1 RANBP2 RANGAP1 RCC1 SEC13 SEH1L TPR XPO1 (see all 36) (see less)
21	Nuclear Pore Complex (NPC) Disassembly	Reactome	AAAS CCNB1 CCNB2 CDK1 NDC1 NEK6 NEK7 NEK9 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POM121 RAE1 RANBP2 SEC13 SEH1L TPR (see all 35) (see less)
22	Transport of the SLBP Dependant Mature mRNA	Reactome	AAAS ALYREF EIF4E NCBP1 NCBP2 NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 NXF1 POM121 RAE1 RANBP2 SEC13 SEH1L SLBP TPR (see all 35) (see less)
23	Rev-mediated nuclear export of HIV RNA	Reactome	AAAS NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POM121 RAE1 RAN RANBP1 RANBP2 RANGAP1 RCC1 SEC13 SEH1L TPR XPO1 (see all 34) (see less)
24	SUMOylation of SUMOylation proteins	Reactome	AAAS NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 PIAS4 POM121 RAE1 RANBP2 SEC13 SEH1L SUMO1 SUMO2 TOPORS TPR UBE2I (see all 34) (see less)
25	Interactions of Vpr with host cellular proteins	Reactome	AAAS BANF1 HMGA1 KPNA1 NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POM121 PSIP1 RAE1 RANBP2 SEC13 SEH1L TPR (see all 33) (see less)
26	Nuclear import of Rev protein	Reactome	AAAS KPNB1 NDC1 NPM1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POM121 RAE1 RAN RANBP2 RCC1 SEC13 SEH1L TPR (see all 33) (see less)
27	Export of Viral Ribonucleoproteins from Nucleus	Reactome	AAAS HSPA1A HSPA1B NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POM121 RAE1 RAN RANBP2 SEC13 SEH1L TPR XPO1 (see all 33) (see less)
28	Vpr-mediated nuclear import of PICs	Reactome	AAAS BANF1 HMGA1 KPNA1 NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POM121 PSIP1 RAE1 RANBP2 SEC13 SEH1L TPR (see all 33) (see less)
29	Transport of Ribonucleoproteins into the Host Nucleus	Reactome	AAAS KPNA1 KPNB1 NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POM121 RAE1 RANBP2 SEC13 SEH1L TPR (see all 31) (see less)
30	Regulation of Glucokinase by Glucokinase Regulatory Protein	Reactome	AAAS GCK GCKR NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POM121 RAE1 RANBP2 SEC13 SEH1L TPR (see all 31) (see less)
31	Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	Reactome	AAAS GCK GCKR NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POM121 RAE1 RANBP2 SEC13 SEH1L TPR (see all 31) (see less)
32	NEP/NS2 Interacts with the Cellular Export Machinery	Reactome	AAAS NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POM121 RAE1 RAN RANBP2 SEC13 SEH1L TPR XPO1 (see all 31) (see less)
33	Postmitotic nuclear pore complex (NPC) reformation	Reactome	AHCTF1 KPNB1 NDC1 NUP107 NUP133 NUP155 NUP160 NUP188 NUP205 NUP35 NUP37 NUP43 NUP54 NUP58 NUP62 NUP85 NUP93 NUP98 POM121 RAN RANGAP1 RCC1 SEC13 SEH1L SUMO1 TNPO1 UBE2I (see all 27) (see less)
34	SUMOylation of transcription factors	Reactome	CDKN2A FOXL2 HIC1 MDM2 MITF MTA1 PIAS1 PIAS2 PIAS3 PIAS4 SP3 SUMO1 SUMO2 SUMO3 TFAP2A TFAP2B TFAP2C TP53 TP53BP1 UBE2I (see all 20) (see less)
35	SUMOylation of DNA methylation proteins	Reactome	BMI1 CBX2 CBX4 CBX8 COMMD3-BMI1 DNMT1 DNMT3A DNMT3B PCGF2 PHC1 PHC2 PHC3 RING1 RNF2 SCMH1 SUMO1 UBE2I (see all 17) (see less)
36	Depolymerization of the Nuclear Lamina	Reactome	CCNB1 CDK1 CNEP1R1 CTDNEP1 EMD LEMD2 LEMD3 LMNA LMNB1 LPIN1 LPIN2 LPIN3 PRKCA PRKCB TMPO (see all 15) (see less)
37	SUMOylation of immune response proteins	Reactome	EIF2AK2 IKBKE IKBKG NFKB2 NFKBIA PIAS3 PIAS4 RELA SUMO1 SUMO3 TOPORS UBE2I (see all 12) (see less)
38	tRNA modification in the mitochondrion	Reactome	GTPBP3 HSD17B10 MTO1 OSGEPL1 PRORP PUS1 TRIT1 TRMT10C TRMT61B TRMU YRDC (see all 11) (see less)
39	Processing and activation of SUMO	Reactome	RWDD3 SAE1 SENP1 SENP2 SENP5 SUMO1 SUMO2 SUMO3 UBA2 UBE2I (see all 10) (see less)
40	tRNA splicing II	PubChem	C2orf49 DDX1 FAM98B RTCB RTRAF TSEN15 TSEN2 TSEN34 TSEN54 ZBTB8OS (see all 10) (see less)
41	Activation of NIMA Kinases NEK9, NEK6, NEK7	Reactome	CCNB1 CCNB2 CDK1 NEK6 NEK7 NEK9 PLK1 (see all 7) (see less)
42	SUMO is transferred from E1 to E2 (UBE2I, UBC9)	Reactome	RWDD3 SAE1 SUMO1 SUMO2 SUMO3 UBA2 UBE2I (see all 7) (see less)
43	SUMO is proteolytically processed	Reactome	SENP1 SENP2 SENP5 SUMO1 SUMO2 SUMO3 (see all 6) (see less)
44	Synthesis of wybutosine at G37 of tRNA(Phe)	Reactome	LCMT2 TRMT5 TYW1 TYW2 TYW3 TYW5 (see all 6) (see less)
45	tRNA processing in the mitochondrion	Reactome	ELAC2 HSD17B10 PRORP TRMT10C TRNT1
46	SUMO is conjugated to E1 (UBA2:SAE1)	Reactome	SAE1 SUMO1 SUMO2 SUMO3 UBA2
47	Inhibition of PKR	Reactome	EIF2AK2

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	NUP35	Nucleoporin 35	Protein Coding	32
2	NUP205	Nucleoporin 205	Protein Coding	32
3	NUP160	Nucleoporin 160	Protein Coding	32
4	NUP188	Nucleoporin 188	Protein Coding	32
5	NUP62	Nucleoporin 62	Protein Coding	32
6	NUP43	Nucleoporin 43	Protein Coding	32
7	NUP98	Nucleoporin 98 And 96 Precursor	Protein Coding	32
8	NUP54	Nucleoporin 54	Protein Coding	32
9	NDC1	NDC1 Transmembrane Nucleoporin	Protein Coding	32
10	NUP133	Nucleoporin 133	Protein Coding	32
11	NUP107	Nucleoporin 107	Protein Coding	32
12	SEC13	SEC13 Homolog, Nuclear Pore And COPII Component	Protein Coding	32
13	NUP37	Nucleoporin 37	Protein Coding	32
14	NUP85	Nucleoporin 85	Protein Coding	32
15	SEH1L	SEH1 Like Nucleoporin	Protein Coding	32
16	NUP155	Nucleoporin 155	Protein Coding	32
17	NUP93	Nucleoporin 93	Protein Coding	32
18	NUP58	Nucleoporin 58	Protein Coding	32
19	POM121	POM121 Transmembrane Nucleoporin	Protein Coding	32
20	NUP50	Nucleoporin 50	Protein Coding	31
21	NUP42	Nucleoporin 42	Protein Coding	31
22	NUP210	Nucleoporin 210	Protein Coding	31
23	NUP88	Nucleoporin 88	Protein Coding	31
24	RANBP2	RAN Binding Protein 2	Protein Coding	31
25	TPR	Translocated Promoter Region, Nuclear Basket Protein	Protein Coding	31
26	NUP214	Nucleoporin 214	Protein Coding	31
27	AAAS	Aladin WD Repeat Nucleoporin	Protein Coding	31
28	RAE1	Ribonucleic Acid Export 1	Protein Coding	31
29	NUP153	Nucleoporin 153	Protein Coding	31
30	SUMO1	Small Ubiquitin Like Modifier 1	Protein Coding	16
31	UBE2I	Ubiquitin Conjugating Enzyme E2 I	Protein Coding	14
32	SUMO2	Small Ubiquitin Like Modifier 2	Protein Coding	12
33	SUMO3	Small Ubiquitin Like Modifier 3	Protein Coding	11
34	PIAS4	Protein Inhibitor Of Activated STAT 4	Protein Coding	8
35	RAN	RAN, Member RAS Oncogene Family	Protein Coding	8
36	NCBP2	Nuclear Cap Binding Protein Subunit 2	Protein Coding	6
37	NCBP1	Nuclear Cap Binding Protein Subunit 1	Protein Coding	6
38	COMMD3-BMI1	COMMD3-BMI1 Readthrough	Protein Coding	6
39	PHC1	Polyhomeotic Homolog 1	Protein Coding	6
40	PHC2	Polyhomeotic Homolog 2	Protein Coding	6
41	SCMH1	Scm Polycomb Group Protein Homolog 1	Protein Coding	6
42	EIF2AK2	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2	Protein Coding	6
43	CBX8	Chromobox 8	Protein Coding	6
44	RANGAP1	Ran GTPase Activating Protein 1	Protein Coding	6
45	RING1	Ring Finger Protein 1	Protein Coding	6
46	RNF2	Ring Finger Protein 2	Protein Coding	6
47	BMI1	BMI1 Proto-Oncogene, Polycomb Ring Finger	Protein Coding	6
48	PCGF2	Polycomb Group Ring Finger 2	Protein Coding	6
49	PHC3	Polyhomeotic Homolog 3	Protein Coding	6
50	CBX2	Chromobox 2	Protein Coding	6
51	CBX4	Chromobox 4	Protein Coding	6
52	PIAS1	Protein Inhibitor Of Activated STAT 1	Protein Coding	6
53	PIAS2	Protein Inhibitor Of Activated STAT 2	Protein Coding	6
54	KPNB1	Karyopherin Subunit Beta 1	Protein Coding	6
55	EIF4E	Eukaryotic Translation Initiation Factor 4E	Protein Coding	5
56	PIAS3	Protein Inhibitor Of Activated STAT 3	Protein Coding	5
57	CPSF4	Cleavage And Polyadenylation Specific Factor 4	Protein Coding	5
58	KPNA1	Karyopherin Subunit Alpha 1	Protein Coding	5
59	ALYREF	Aly/REF Export Factor	Protein Coding	4
60	NXF1	Nuclear RNA Export Factor 1	Protein Coding	4
61	UBA2	Ubiquitin Like Modifier Activating Enzyme 2	Protein Coding	4
62	SAE1	SUMO1 Activating Enzyme Subunit 1	Protein Coding	4
63	TOPORS	TOP1 Binding Arginine/Serine Rich Protein, E3 Ubiquitin Ligase	Protein Coding	4
64	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	4
65	MDM2	MDM2 Proto-Oncogene	Protein Coding	4
66	NPM1	Nucleophosmin 1	Protein Coding	4
67	PML	PML Nuclear Body Scaffold	Protein Coding	4
68	CPSF1	Cleavage And Polyadenylation Specific Factor 1	Protein Coding	4
69	CCNB1	Cyclin B1	Protein Coding	4
70	CDK1	Cyclin Dependent Kinase 1	Protein Coding	4
71	RCC1	Regulator Of Chromosome Condensation 1	Protein Coding	4
72	XPO1	Exportin 1	Protein Coding	4
73	STAG1	STAG1 Cohesin Complex Component	Protein Coding	3
74	CETN2	Centrin 2	Protein Coding	3
75	STAG2	STAG2 Cohesin Complex Component	Protein Coding	3
76	CHD3	Chromodomain Helicase DNA Binding Protein 3	Protein Coding	3
77	H4C16	H4 Histone 16	Protein Coding	3
78	PARP1	Poly(ADP-Ribose) Polymerase 1	Protein Coding	3
79	RNF168	Ring Finger Protein 168	Protein Coding	3
80	DNMT1	DNA Methyltransferase 1	Protein Coding	3
81	DNMT3A	DNA Methyltransferase 3 Alpha	Protein Coding	3
82	DNMT3B	DNA Methyltransferase 3 Beta	Protein Coding	3
83	NSMCE1	NSE1 Component Of SMC5/6 Complex	Protein Coding	3
84	SENP5	SUMO Specific Peptidase 5	Protein Coding	3
85	SMC5	Structural Maintenance Of Chromosomes 5	Protein Coding	3
86	SATB2	SATB Homeobox 2	Protein Coding	3
87	CBX5	Chromobox 5	Protein Coding	3
88	SUZ12	SUZ12 Polycomb Repressive Complex 2 Subunit	Protein Coding	3
89	RWDD3	RWD Domain Containing 3	Protein Coding	3
90	NSMCE2	NSE2 SUMO Ligase Component Of SMC5/6 Complex	Protein Coding	3
91	SENP1	SUMO Specific Peptidase 1	Protein Coding	3
92	HDAC1	Histone Deacetylase 1	Protein Coding	3
93	HDAC2	Histone Deacetylase 2	Protein Coding	3
94	HIC1	HIC ZBTB Transcriptional Repressor 1	Protein Coding	3
95	HNRNPC	Heterogeneous Nuclear Ribonucleoprotein C	Protein Coding	3
96	HNRNPK	Heterogeneous Nuclear Ribonucleoprotein K	Protein Coding	3
97	BIRC5	Baculoviral IAP Repeat Containing 5	Protein Coding	3
98	INCENP	Inner Centromere Protein	Protein Coding	3
99	MITF	Melanocyte Inducing Transcription Factor	Protein Coding	3
100	NFKB2	Nuclear Factor Kappa B Subunit 2	Protein Coding	3
101	NFKBIA	NFKB Inhibitor Alpha	Protein Coding	3
102	EID3	EP300 Interacting Inhibitor Of Differentiation 3	Protein Coding	3
103	PCNA	Proliferating Cell Nuclear Antigen	Protein Coding	3
104	HDAC7	Histone Deacetylase 7	Protein Coding	3
105	NOP58	NOP58 Ribonucleoprotein	Protein Coding	3
106	NSMCE4A	NSE4A Component Of SMC5/6 Complex	Protein Coding	3
107	CDCA8	Cell Division Cycle Associated 8	Protein Coding	3
108	H4C15	H4 Clustered Histone 15	Protein Coding	3
109	NSMCE3	NSE3 Component Of SMC5/6 Complex	Protein Coding	3
110	RAD21	RAD21 Cohesin Complex Component	Protein Coding	3
111	RAD52	RAD52 DNA Repair Protein	Protein Coding	3
112	SENP2	SUMO Specific Peptidase 2	Protein Coding	3
113	RELA	RELA Proto-Oncogene, NF-KB Subunit	Protein Coding	3
114	TRIM27	Tripartite Motif Containing 27	Protein Coding	3
115	RPA1	Replication Protein A1	Protein Coding	3
116	SATB1	SATB Homeobox 1	Protein Coding	3
117	BLM	BLM RecQ Like Helicase	Protein Coding	3
118	SP3	Sp3 Transcription Factor	Protein Coding	3
119	SP100	SP100 Nuclear Antigen	Protein Coding	3
120	FOXL2	Forkhead Box L2	Protein Coding	3
121	BRCA1	BRCA1 DNA Repair Associated	Protein Coding	3
122	AURKA	Aurora Kinase A	Protein Coding	3
123	TDG	Thymine DNA Glycosylase	Protein Coding	3
124	TFAP2A	Transcription Factor AP-2 Alpha	Protein Coding	3
125	TFAP2B	Transcription Factor AP-2 Beta	Protein Coding	3
126	TFAP2C	Transcription Factor AP-2 Gamma	Protein Coding	3
127	TOP1	DNA Topoisomerase I	Protein Coding	3
128	TOP2A	DNA Topoisomerase II Alpha	Protein Coding	3
129	TOP2B	DNA Topoisomerase II Beta	Protein Coding	3
130	TP53	Tumor Protein P53	Protein Coding	3
131	TP53BP1	Tumor Protein P53 Binding Protein 1	Protein Coding	3
132	VHL	Von Hippel-Lindau Tumor Suppressor	Protein Coding	3
133	WRN	WRN RecQ Like Helicase	Protein Coding	3
134	XPC	XPC Complex Subunit, DNA Damage Recognition And Repair Factor	Protein Coding	3
135	XRCC4	X-Ray Repair Cross Complementing 4	Protein Coding	3
136	SMC6	Structural Maintenance Of Chromosomes 6	Protein Coding	3
137	SMC1A	Structural Maintenance Of Chromosomes 1A	Protein Coding	3
138	H4C9	H4 Clustered Histone 9	Protein Coding	3
139	H4C1	H4 Clustered Histone 1	Protein Coding	3
140	H4C4	H4 Clustered Histone 4	Protein Coding	3
141	H4C6	H4 Clustered Histone 6	Protein Coding	3
142	H4C12	H4 Clustered Histone 12	Protein Coding	3
143	H4C11	H4 Clustered Histone 11	Protein Coding	3
144	H4C3	H4 Clustered Histone 3	Protein Coding	3
145	H4C8	H4 Clustered Histone 8	Protein Coding	3
146	H4C2	H4 Clustered Histone 2	Protein Coding	3
147	H4C5	H4 Clustered Histone 5	Protein Coding	3
148	H4C13	H4 Clustered Histone 13	Protein Coding	3
149	H4C14	H4 Clustered Histone 14	Protein Coding	3
150	L3MBTL2	L3MBTL Histone Methyl-Lysine Binding Protein 2	Protein Coding	3
151	IKBKG	Inhibitor Of Nuclear Factor Kappa B Kinase Regulatory Subunit Gamma	Protein Coding	3
152	HERC2	HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 2	Protein Coding	3
153	MTA1	Metastasis Associated 1	Protein Coding	3
154	SMC3	Structural Maintenance Of Chromosomes 3	Protein Coding	3
155	ZBED1	Zinc Finger BED-Type Containing 1	Protein Coding	3
156	AURKB	Aurora Kinase B	Protein Coding	3
157	IKBKE	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Epsilon	Protein Coding	3
158	MDC1	Mediator Of DNA Damage Checkpoint 1	Protein Coding	3
159	HDAC4	Histone Deacetylase 4	Protein Coding	3
160	TSEN15	TRNA Splicing Endonuclease Subunit 15	Protein Coding	3
161	TYW3	TRNA-YW Synthesizing Protein 3 Homolog	Protein Coding	3
162	TYW5	TRNA-YW Synthesizing Protein 5	Protein Coding	3
163	DDX1	DEAD-Box Helicase 1	Protein Coding	3
164	FAM98B	Family With Sequence Similarity 98 Member B	Protein Coding	3
165	TSEN54	TRNA Splicing Endonuclease Subunit 54	Protein Coding	3
166	HSD17B10	Hydroxysteroid 17-Beta Dehydrogenase 10	Protein Coding	3
167	ZBTB8OS	Zinc Finger And BTB Domain Containing 8 Opposite Strand	Protein Coding	3
168	TRNT1	TRNA Nucleotidyl Transferase 1	Protein Coding	3
169	RTCB	RNA 2'',3''-Cyclic Phosphate And 5''-OH Ligase	Protein Coding	3
170	RTRAF	RNA Transcription, Translation And Transport Factor	Protein Coding	3
171	TRIT1	TRNA Isopentenyltransferase 1	Protein Coding	3
172	TRMT10C	TRNA Methyltransferase 10C, Mitochondrial RNase P Subunit	Protein Coding	3
173	TYW2	TRNA Wybutosine-Synthesizing Protein 2	Protein Coding	3
174	TYW1	TRNA-YW Synthesizing Protein 1 Homolog	Protein Coding	3
175	TRMT5	TRNA Methyltransferase 5	Protein Coding	3
176	ELAC2	ElaC Ribonuclease Z 2	Protein Coding	3
177	TSEN34	TRNA Splicing Endonuclease Subunit 34	Protein Coding	3
178	C2orf49	Chromosome 2 Open Reading Frame 49	Protein Coding	3
179	PUS1	Pseudouridine Synthase 1	Protein Coding	3
180	TSEN2	TRNA Splicing Endonuclease Subunit 2	Protein Coding	3
181	PRORP	Protein Only RNase P Catalytic Subunit	Protein Coding	3
182	LCMT2	Leucine Carboxyl Methyltransferase 2	Protein Coding	3
183	NEK6	NIMA Related Kinase 6	Protein Coding	3
184	NEK7	NIMA Related Kinase 7	Protein Coding	3
185	BANF1	Barrier To Autointegration Nuclear Assembly Factor 1	Protein Coding	3
186	CCNB2	Cyclin B2	Protein Coding	3
187	NEK9	NIMA Related Kinase 9	Protein Coding	3
188	NR1H3	Nuclear Receptor Subfamily 1 Group H Member 3	Protein Coding	2
189	TRIM28	Tripartite Motif Containing 28	Protein Coding	2
190	NCOA2	Nuclear Receptor Coactivator 2	Protein Coding	2
191	DDX17	DEAD-Box Helicase 17	Protein Coding	2
192	PPARGC1A	PPARG Coactivator 1 Alpha	Protein Coding	2
193	PARK7	Parkinsonism Associated Deglycase	Protein Coding	2
194	UHRF2	Ubiquitin Like With PHD And Ring Finger Domains 2	Protein Coding	2
195	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	2
196	CTBP1	C-Terminal Binding Protein 1	Protein Coding	2
197	DAXX	Death Domain Associated Protein	Protein Coding	2
198	DDX5	DEAD-Box Helicase 5	Protein Coding	2
199	EP300	EP300 Lysine Acetyltransferase	Protein Coding	2
200	ESR1	Estrogen Receptor 1	Protein Coding	2
201	NR5A2	Nuclear Receptor Subfamily 5 Group A Member 2	Protein Coding	2
202	NR5A1	Nuclear Receptor Subfamily 5 Group A Member 1	Protein Coding	2
203	SIN3A	SIN3 Transcription Regulator Family Member A	Protein Coding	2
204	HIPK2	Homeodomain Interacting Protein Kinase 2	Protein Coding	2
205	NR3C1	Nuclear Receptor Subfamily 3 Group C Member 1	Protein Coding	2
206	ING2	Inhibitor Of Growth Family Member 2	Protein Coding	2
207	AR	Androgen Receptor	Protein Coding	2
208	MBD1	Methyl-CpG Binding Domain Protein 1	Protein Coding	2
209	NR3C2	Nuclear Receptor Subfamily 3 Group C Member 2	Protein Coding	2
210	NR4A2	Nuclear Receptor Subfamily 4 Group A Member 2	Protein Coding	2
211	PGR	Progesterone Receptor	Protein Coding	2
212	PPARA	Peroxisome Proliferator Activated Receptor Alpha	Protein Coding	2
213	PPARG	Peroxisome Proliferator Activated Receptor Gamma	Protein Coding	2
214	MRTFA	Myocardin Related Transcription Factor A	Protein Coding	2
215	RARA	Retinoic Acid Receptor Alpha	Protein Coding	2
216	ZNF350	Zinc Finger Protein 350	Protein Coding	2
217	RORA	RAR Related Orphan Receptor A	Protein Coding	2
218	RXRA	Retinoid X Receptor Alpha	Protein Coding	2
219	SAFB	Scaffold Attachment Factor B	Protein Coding	2
220	THRA	Thyroid Hormone Receptor Alpha	Protein Coding	2
221	THRB	Thyroid Hormone Receptor Beta	Protein Coding	2
222	NR2C1	Nuclear Receptor Subfamily 2 Group C Member 1	Protein Coding	2
223	NR1H2	Nuclear Receptor Subfamily 1 Group H Member 2	Protein Coding	2
224	VDR	Vitamin D Receptor	Protein Coding	2
225	ZNF131	Zinc Finger Protein 131	Protein Coding	2
226	NRIP1	Nuclear Receptor Interacting Protein 1	Protein Coding	2
227	NCOA1	Nuclear Receptor Coactivator 1	Protein Coding	2
228	NR1I2	Nuclear Receptor Subfamily 1 Group I Member 2	Protein Coding	2
229	NCOR2	Nuclear Receptor Corepressor 2	Protein Coding	2
230	NR1H4	Nuclear Receptor Subfamily 1 Group H Member 4	Protein Coding	2
231	CASP8AP2	Caspase 8 Associated Protein 2	Protein Coding	2
232	POP7	POP7 Ribonuclease P/MRP Subunit	Protein Coding	2
233	RPP30	Ribonuclease P/MRP Subunit P30	Protein Coding	2
234	RPP38	Ribonuclease P/MRP Subunit P38	Protein Coding	2
235	POP4	POP4 Ribonuclease P/MRP Subunit	Protein Coding	2
236	WDR4	WDR4 TRNA N7-Guanosine Methyltransferase Non-Catalytic Subunit	Protein Coding	2
237	RPP40	Ribonuclease P/MRP Subunit P40	Protein Coding	2
238	POP1	POP1 Ribonuclease P/MRP Subunit	Protein Coding	2
239	CLP1	Cleavage Factor Polyribonucleotide Kinase Subunit 1	Protein Coding	2
240	RPP14	Ribonuclease P/MRP Subunit P14	Protein Coding	2
241	XPOT	Exportin For TRNA	Protein Coding	2
242	TP53RK	TP53 Regulating Kinase	Protein Coding	2
243	ADAT3	Adenosine Deaminase TRNA Specific 3	Protein Coding	2
244	TRMT61A	TRNA Methyltransferase 61A	Protein Coding	2
245	ADAT2	Adenosine Deaminase TRNA Specific 2	Protein Coding	2
246	CSTF2	Cleavage Stimulation Factor Subunit 2	Protein Coding	2
247	TRMT44	TRNA Methyltransferase 44 Homolog	Protein Coding	2
248	TRDMT1	TRNA Aspartic Acid Methyltransferase 1	Protein Coding	2
249	EPRS1	Glutamyl-Prolyl-TRNA Synthetase 1	Protein Coding	2
250	NSUN6	NOP2/Sun RNA Methyltransferase 6	Protein Coding	2
251	ADAT1	Adenosine Deaminase TRNA Specific 1	Protein Coding	2
252	FTSJ1	FtsJ RNA 2''-O-Methyltransferase 1	Protein Coding	2
253	MTO1	Mitochondrial TRNA Translation Optimization 1	Protein Coding	2
254	CTU2	Cytosolic Thiouridylase Subunit 2	Protein Coding	2
255	METTL1	Methyltransferase 1, TRNA Methylguanosine	Protein Coding	2
256	TPRKB	TP53RK Binding Protein	Protein Coding	2
257	POP5	POP5 Ribonuclease P/MRP Subunit	Protein Coding	2
258	TRMT112	TRNA Methyltransferase Activator Subunit 11-2	Protein Coding	2
259	TRMT6	TRNA Methyltransferase 6 Non-Catalytic Subunit	Protein Coding	2
260	TRMT13	TRNA Methyltransferase 13	Protein Coding	2
261	PUS7	Pseudouridine Synthase 7	Protein Coding	2
262	NSUN2	NOP2/Sun RNA Methyltransferase 2	Protein Coding	2
263	CDKAL1	CDKAL1 Threonylcarbamoyladenosine TRNA Methylthiotransferase	Protein Coding	2
264	RPP25	Ribonuclease P/MRP Subunit P25	Protein Coding	2
265	DUS2	Dihydrouridine Synthase 2	Protein Coding	2
266	THG1L	TRNA-Histidine Guanylyltransferase 1 Like	Protein Coding	2
267	TRMT61B	TRNA Methyltransferase 61B	Protein Coding	2
268	TRMT1	TRNA Methyltransferase 1	Protein Coding	2
269	OSGEP	O-Sialoglycoprotein Endopeptidase	Protein Coding	2
270	TRMU	TRNA Mitochondrial 2-Thiouridylase	Protein Coding	2
271	TRMT9B	TRNA Methyltransferase 9B (Putative)	Protein Coding	2
272	TRMT11	TRNA Methyltransferase 11	Protein Coding	2
273	THADA	THADA Armadillo Repeat Containing	Protein Coding	2
274	OSGEPL1	O-Sialoglycoprotein Endopeptidase Like 1	Protein Coding	2
275	QTRT2	Queuine TRNA-Ribosyltransferase Accessory Subunit 2	Protein Coding	2
276	YRDC	YrdC N6-Threonylcarbamoyltransferase Domain Containing	Protein Coding	2
277	RPP21	Ribonuclease P Subunit P21	Protein Coding	2
278	URM1	Ubiquitin Related Modifier 1	Protein Coding	2
279	QTRT1	Queuine TRNA-Ribosyltransferase Catalytic Subunit 1	Protein Coding	2
280	LAGE3	L Antigen Family Member 3	Protein Coding	2
281	PUS3	Pseudouridine Synthase 3	Protein Coding	2
282	QNG1	Q-Nucleotide N-Glycosylase 1	Protein Coding	2
283	GON7	GON7 Subunit Of KEOPS Complex	Protein Coding	2
284	GTPBP3	GTP Binding Protein 3, Mitochondrial	Protein Coding	2
285	CTU1	Cytosolic Thiouridylase Subunit 1	Protein Coding	2
286	ALKBH8	AlkB Homolog 8, TRNA Methyltransferase	Protein Coding	2
287	TRMT10A	TRNA Methyltransferase 10A	Protein Coding	2
288	KPNA2	Karyopherin Subunit Alpha 2	Protein Coding	2
289	KPNA3	Karyopherin Subunit Alpha 3	Protein Coding	2
290	KPNA4	Karyopherin Subunit Alpha 4	Protein Coding	2
291	KPNA5	Karyopherin Subunit Alpha 5	Protein Coding	2
292	KPNA7	Karyopherin Subunit Alpha 7	Protein Coding	2
293	ISG15	ISG15 Ubiquitin Like Modifier	Protein Coding	2
294	SNUPN	Snurportin 1	Protein Coding	2
295	PRMT5	Protein Arginine Methyltransferase 5	Protein Coding	2
296	DDX20	DEAD-Box Helicase 20	Protein Coding	2
297	CLNS1A	Chloride Nucleotide-Sensitive Channel 1A	Protein Coding	2
298	GEMIN5	Gem Nuclear Organelle Associated Protein 5	Protein Coding	2
299	GEMIN4	Gem Nuclear Organelle Associated Protein 4	Protein Coding	2
300	PHAX	Phosphorylated Adaptor For RNA Export	Protein Coding	2
301	GEMIN8	Gem Nuclear Organelle Associated Protein 8	Protein Coding	2
302	SMN1	Survival Of Motor Neuron 1, Telomeric	Protein Coding	2
303	SMN2	Survival Of Motor Neuron 2, Centromeric	Protein Coding	2
304	SNRPB	Small Nuclear Ribonucleoprotein Polypeptides B And B1	Protein Coding	2
305	SNRPD1	Small Nuclear Ribonucleoprotein D1 Polypeptide	Protein Coding	2
306	SNRPD2	Small Nuclear Ribonucleoprotein D2 Polypeptide	Protein Coding	2
307	SNRPD3	Small Nuclear Ribonucleoprotein D3 Polypeptide	Protein Coding	2
308	SNRPE	Small Nuclear Ribonucleoprotein Polypeptide E	Protein Coding	2
309	SNRPF	Small Nuclear Ribonucleoprotein Polypeptide F	Protein Coding	2
310	SNRPG	Small Nuclear Ribonucleoprotein Polypeptide G	Protein Coding	2
311	WDR77	WD Repeat Domain 77	Protein Coding	2
312	GEMIN7	Gem Nuclear Organelle Associated Protein 7	Protein Coding	2
313	GEMIN6	Gem Nuclear Organelle Associated Protein 6	Protein Coding	2
314	GEMIN2	Gem Nuclear Organelle Associated Protein 2	Protein Coding	2
315	TGS1	Trimethylguanosine Synthase 1	Protein Coding	2
316	EMD	Emerin	Protein Coding	2
317	LEMD2	LEM Domain Nuclear Envelope Protein 2	Protein Coding	2
318	LPIN1	Lipin 1	Protein Coding	2
319	CTDNEP1	CTD Nuclear Envelope Phosphatase 1	Protein Coding	2
320	LEMD3	LEM Domain Containing 3	Protein Coding	2
321	CNEP1R1	CTD Nuclear Envelope Phosphatase 1 Regulatory Subunit 1	Protein Coding	2
322	LMNA	Lamin A/C	Protein Coding	2
323	LMNB1	Lamin B1	Protein Coding	2
324	PLK1	Polo Like Kinase 1	Protein Coding	2
325	PRKCA	Protein Kinase C Alpha	Protein Coding	2
326	PRKCB	Protein Kinase C Beta	Protein Coding	2
327	LPIN3	Lipin 3	Protein Coding	2
328	TMPO	Thymopoietin	Protein Coding	2
329	LPIN2	Lipin 2	Protein Coding	2
330	CPSF3	Cleavage And Polyadenylation Specific Factor 3	Protein Coding	2
331	CPSF2	Cleavage And Polyadenylation Specific Factor 2	Protein Coding	2
332	WDR33	WD Repeat Domain 33	Protein Coding	2
333	SLBP	Stem-Loop Histone MRNA Binding Protein	Protein Coding	2
334	FIP1L1	Factor Interacting With PAPOLA And CPSF1	Protein Coding	2
335	SYMPK	Symplekin Scaffold Protein	Protein Coding	2
336	RANBP1	RAN Binding Protein 1	Protein Coding	2
337	PSIP1	PC4 And SRSF1 Interacting Protein 1	Protein Coding	2
338	HMGA1	High Mobility Group AT-Hook 1	Protein Coding	2
339	GCK	Glucokinase	Protein Coding	2
340	GCKR	Glucokinase Regulator	Protein Coding	2
341	USP18	Ubiquitin Specific Peptidase 18	Protein Coding	1
342	EIF4A1	Eukaryotic Translation Initiation Factor 4A1	Protein Coding	1
343	EIF4A2	Eukaryotic Translation Initiation Factor 4A2	Protein Coding	1
344	EIF4G1	Eukaryotic Translation Initiation Factor 4 Gamma 1	Protein Coding	1
345	EIF4G2	Eukaryotic Translation Initiation Factor 4 Gamma 2	Protein Coding	1
346	FLNB	Filamin B	Protein Coding	1
347	RIGI	RNA Sensor RIG-I	Protein Coding	1
348	ARIH1	Ariadne RBR E3 Ubiquitin Protein Ligase 1	Protein Coding	1
349	EIF4E3	Eukaryotic Translation Initiation Factor 4E Family Member 3	Protein Coding	1
350	IFIT1	Interferon Induced Protein With Tetratricopeptide Repeats 1	Protein Coding	1
351	IRF3	Interferon Regulatory Factor 3	Protein Coding	1
352	JAK1	Janus Kinase 1	Protein Coding	1
353	MX1	MX Dynamin Like GTPase 1	Protein Coding	1
354	MX2	MX Dynamin Like GTPase 2	Protein Coding	1
355	NEDD4	NEDD4 E3 Ubiquitin Protein Ligase	Protein Coding	1
356	HERC5	HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 5	Protein Coding	1
357	PIN1	Peptidylprolyl Cis/Trans Isomerase, NIMA-Interacting 1	Protein Coding	1
358	PLCG1	Phospholipase C Gamma 1	Protein Coding	1
359	PPM1B	Protein Phosphatase, Mg2+/Mn2+ Dependent 1B	Protein Coding	1
360	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
361	RPS27A	Ribosomal Protein S27a	Protein Coding	1
362	STAT1	Signal Transducer And Activator Of Transcription 1	Protein Coding	1
363	UBA52	Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1	Protein Coding	1
364	UBB	Ubiquitin B	Protein Coding	1
365	UBC	Ubiquitin C	Protein Coding	1
366	UBA7	Ubiquitin Like Modifier Activating Enzyme 7	Protein Coding	1
367	UBE2E1	Ubiquitin Conjugating Enzyme E2 E1	Protein Coding	1
368	UBE2N	Ubiquitin Conjugating Enzyme E2 N	Protein Coding	1
369	TRIM25	Tripartite Motif Containing 25	Protein Coding	1
370	EIF4G3	Eukaryotic Translation Initiation Factor 4 Gamma 3	Protein Coding	1
371	BECN1	Beclin 1	Protein Coding	1
372	UBE2L6	Ubiquitin Conjugating Enzyme E2 L6	Protein Coding	1
373	EIF4E2	Eukaryotic Translation Initiation Factor 4E Family Member 2	Protein Coding	1
374	EIF4A3	Eukaryotic Translation Initiation Factor 4A3	Protein Coding	1
375	VRK1	VRK Serine/Threonine Kinase 1	Protein Coding	1
376	VRK2	VRK Serine/Threonine Kinase 2	Protein Coding	1
377	GTF2F1	General Transcription Factor IIF Subunit 1	Protein Coding	1
378	GTF2F2	General Transcription Factor IIF Subunit 2	Protein Coding	1
379	POLR2A	RNA Polymerase II Subunit A	Protein Coding	1
380	POLR2B	RNA Polymerase II Subunit B	Protein Coding	1
381	POLR2C	RNA Polymerase II Subunit C	Protein Coding	1
382	POLR2D	RNA Polymerase II Subunit D	Protein Coding	1
383	POLR2E	RNA Polymerase II, I And III Subunit E	Protein Coding	1
384	POLR2F	RNA Polymerase II, I And III Subunit F	Protein Coding	1
385	POLR2G	RNA Polymerase II Subunit G	Protein Coding	1
386	POLR2H	RNA Polymerase II, I And III Subunit H	Protein Coding	1
387	POLR2I	RNA Polymerase II Subunit I	Protein Coding	1
388	POLR2J	RNA Polymerase II Subunit J	Protein Coding	1
389	POLR2K	RNA Polymerase II, I And III Subunit K	Protein Coding	1
390	POLR2L	RNA Polymerase II, I And III Subunit L	Protein Coding	1
391	PABPN1	Poly(A) Binding Protein Nuclear 1	Protein Coding	1
392	HSPA1A	Heat Shock Protein Family A (Hsp70) Member 1A	Protein Coding	1
393	HSPA1B	Heat Shock Protein Family A (Hsp70) Member 1B	Protein Coding	1
394	AHCTF1	AT-Hook Containing Transcription Factor 1	Protein Coding	1
395	TNPO1	Transportin 1	Protein Coding	1

Disorders associated with Transport of the SLBP independent Mature mRNA SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Influenza	Direct
2	Human immunodeficiency virus infectious disease	Direct
3	Papillary carcinoma	Direct
4	Galloway-mowat syndrome	Enrichment	GON7, LAGE3, NUP107, NUP133, OSGEP, TP53RK, TPRKB, WDR4, YRDC	16.00
5	Genetic steroid-resistant nephrotic syndrome	Enrichment	NUP107, NUP133, NUP160, NUP205, NUP37, NUP85, NUP93	16.00
6	Pontocerebellar hypoplasia, type 2e	Enrichment	TSEN15, TSEN2, TSEN34, TSEN54	10.52
7	Li-fraumeni syndrome	Enrichment	CDKN2A, MDM2, TP53	7.26
8	Galloway-mowat syndrome 1	Enrichment	GON7, OSGEP, WDR4	6.47
9	Ectodermal dysplasia and immune deficiency	Enrichment	IKBKG, NFKBIA	6.14
10	Emery-dreifuss muscular dystrophy 1, x-linked	Enrichment	EMD, LMNA	5.16
11	Emery-dreifuss muscular dystrophy	Enrichment	EMD, LMNA	5.16
12	Myeloma, multiple	Enrichment	AURKA, CREBBP, DNMT3A, HDAC4, NCOR2, RXRA, TP53	5.02
13	Cornelia de lange syndrome 1	Enrichment	RAD21, SMC1A, SMC3	4.84
14	Cornelia de lange syndrome	Enrichment	RAD21, SMC1A, SMC3	4.84
15	Familial infantile bilateral striatal necrosis	Enrichment	NUP54, NUP62	4.64
16	Tessadori-bicknell-van haaften neurodevelopmental syndrome 1	Enrichment	H4C1, H4C3	4.57
17	Tessadori-bicknell-van haaften neurodevelopmental syndrome 2	Enrichment	H4C1, H4C11	4.57
18	Adrenocortical carcinoma	Enrichment	CDKN2A, TP53	4.51
19	Microcephalic primordial dwarfism-insulin resistance syndrome	Enrichment	NSMCE2, XRCC4	4.50
20	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	CDKN2A, TP53	4.36
21	Spinal muscular atrophy, type iii	Enrichment	SMN1, SMN2	4.35
22	Spinal muscular atrophy, type i	Enrichment	SMN1, SMN2	4.35
23	Spinal muscular atrophy, type ii	Enrichment	SMN1, SMN2	4.35
24	Spinal muscular atrophy, type iv	Enrichment	SMN1, SMN2	4.35
25	Gliosarcoma	Enrichment	DNMT3A, NFKBIA, PPARG, TP53	4.29
26	Giant cell glioblastoma	Enrichment	DNMT3A, NFKBIA, PPARG, TP53	4.18
27	Pontocerebellar hypoplasia	Enrichment	TSEN2, TSEN54	4.13
28	Tessadori-bicknell-van haaften neurodevelopmental syndrome 4	Enrichment	H4C1, H4C9	4.09
29	Tessadori-bicknell-van haaften neurodevelopmental syndrome 3	Enrichment	H4C1, H4C5	4.09
30	Melanoma	Enrichment	CDKN2A, MITF	4.03
31	Lip and oral cavity carcinoma	Enrichment	CDKN2A, TP53	3.87
32	Spinal muscular atrophy	Enrichment	SMN1, SMN2	3.83
33	Neuromuscular disease	Enrichment	EMD, LMNA	3.76
34	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	EMD, LMNA	3.71
35	Ovarian cancer	Enrichment	BLM, BRCA1, CDKN2A, WRN, XPC	3.57
36	Melanoma, cutaneous malignant 1	Enrichment	CDKN2A, MITF	3.56
37	46,xy complete gonadal dysgenesis	Enrichment	AR, CBX2, NR5A1	3.43
38	Hsd10 mitochondrial disease	Enrichment	HSD17B10	3.43
39	Combined oxidative phosphorylation deficiency 30	Enrichment	TRMT10C	3.43
40	Syndromic x-linked intellectual disability type 10	Enrichment	HSD17B10	3.43
41	Sideroblastic anemia with b-cell immunodeficiency, periodic fevers, and developmental delay	Enrichment	TRNT1	3.43
42	Prostate cancer, hereditary, 2	Enrichment	ELAC2	3.43
43	Combined oxidative phosphorylation deficiency 17	Enrichment	ELAC2	3.43
44	Retinitis pigmentosa and erythrocytic microcytosis	Enrichment	TRNT1	3.43
45	Congenital sideroblastic anemia-b-cell immunodeficiency-periodic fever-developmental delay syndrome	Enrichment	TRNT1	3.43
46	Orofacial cleft 10	Enrichment	SUMO1	3.43
47	Peripheral neuropathy with variable spasticity, exercise intolerance, and developmental delay	Enrichment	TRMT5	3.35
48	Wiedemann-steiner syndrome	Enrichment	SMC1A, SMC3	3.33
49	Arthrogryposis, perthes disease, and upward gaze palsy	Enrichment	NEK9	3.29
50	Nevus comedonicus	Enrichment	NEK9	3.29
51	Lethal congenital contracture syndrome 10	Enrichment	NEK9	3.29
52	Nasopharyngeal carcinoma	Enrichment	NFKBIA, TP53	3.27
53	Pancreatic cancer	Enrichment	CDKN2A, TP53	3.22
54	Acute promyelocytic leukemia	Enrichment	NPM1, PML, RARA	3.20
55	Intellectual developmental disorder, autosomal recessive 2	Enrichment	TRNT1	3.13
56	Combined oxidative phosphorylation deficiency 54	Enrichment	PRORP	3.13
57	Chromosome 19q13.11 deletion syndrome, distal	Enrichment	UBA2	3.13
58	Pontocerebellar hypoplasia, type 2a	Enrichment	TSEN54	3.13
59	Pontocerebellar hypoplasia, type 2b	Enrichment	TSEN2	3.13
60	Pontocerebellar hypoplasia, type 2c	Enrichment	TSEN34	3.13
61	Pontocerebellar hypoplasia, type 2f	Enrichment	TSEN15	3.13
62	Pontocerebellar hypoplasia, type 5	Enrichment	TSEN54	3.13
63	Tsen54 pontocerebellar hypoplasia	Enrichment	TSEN54	3.13
64	Combined oxidative phosphorylation deficiency 10	Enrichment	MTO1	3.09
65	Combined oxidative phosphorylation deficiency 23	Enrichment	GTPBP3	3.09
66	Deafness, aminoglycoside-induced	Enrichment	TRMU	3.09
67	Myopathy, lactic acidosis, and sideroblastic anemia	Enrichment	PUS1	3.09
68	Bladder cancer	Enrichment	CDKN2A, TP53	3.09
69	Incontinentia pigmenti	Enrichment	IKBKG	3.05
70	Autoinflammatory disease, systemic, x-linked	Enrichment	IKBKG	3.05
71	Leukoencephalopathy, developmental delay, and episodic neurologic regression syndrome	Enrichment	EIF2AK2	3.05
72	Ectodermal dysplasia and immunodeficiency 1	Enrichment	IKBKG	3.05
73	Retinitis pigmentosa 31	Enrichment	TOPORS	3.05
74	Deficiency in anterior pituitary function - variable immunodeficiency syndrome	Enrichment	NFKB2	3.05
75	Dystonia 33	Enrichment	EIF2AK2	3.05
76	Inherited cancer-predisposing syndrome	Enrichment	CDKN2A, MITF, TP53	3.04
77	Rare genetic intellectual disability	Enrichment	CREBBP, DNMT3A, EP300	3.01
78	Au-kline syndrome	Enrichment	HNRNPK, VHL	2.97
79	Aplasia cutis congenita, nonsyndromic	Enrichment	UBA2	2.96
80	Leukodystrophy, demyelinating, adult-onset, autosomal dominant, typical	Enrichment	LMNB1	2.96
81	Buschke-ollendorff syndrome	Enrichment	LEMD3	2.96
82	Teeth, supernumerary	Enrichment	LEMD2	2.96
83	Marbach-rustad progeroid syndrome	Enrichment	LEMD2	2.96
84	Adult onset demyelinating leukodystrophy	Enrichment	LMNB1	2.96
85	Majeed syndrome	Enrichment	LPIN2	2.96
86	Microcephaly 26, primary, autosomal dominant	Enrichment	LMNB1	2.96
87	Atypical werner syndrome	Enrichment	LMNA	2.96
88	Melorheostosis with osteopoikilosis	Enrichment	LEMD3	2.96
89	Mandibuloacral dysplasia	Enrichment	LMNA	2.96
90	Atrioventricular block	Enrichment	LMNA	2.96
91	Lmna-related cardiocutaneous progeria syndrome	Enrichment	LMNA	2.96
92	Isolated osteopoikilosis	Enrichment	LEMD3	2.96
93	Autosomal semi-dominant severe lipodystrophic laminopathy	Enrichment	LMNA	2.96
94	Autosomal recessive axonal hereditary motor and sensory neuropathy	Enrichment	LMNA	2.96
95	Laminopathy	Enrichment	LMNA	2.96
96	Colorectal cancer	Enrichment	AURKA, BLM, BRCA1, EP300, PPARG, TP53	2.94
97	46,xy sex reversal 5	Enrichment	CBX2	2.90
98	Microcephaly 11, primary, autosomal recessive	Enrichment	PHC1	2.90
99	Luo-schoch-yamamoto syndrome	Enrichment	RNF2	2.90
100	Heyn-sproul-jackson syndrome	Enrichment	DNMT3A	2.90
101	Turnpenny-fry syndrome	Enrichment	PCGF2	2.90
102	Tooth agenesis	Enrichment	RANBP2, SUMO1	2.86
103	Complex neurodevelopmental disorder	Enrichment	H4C3, H4C5, H4C9, HNRNPC, NR4A2, RNF2, RORA	2.84
104	Hemolytic-uremic syndrome	Enrichment	TSEN2	2.83
105	Blepharophimosis, ptosis, and epicanthus inversus	Enrichment	FOXL2	2.83
106	Char syndrome	Enrichment	TFAP2B	2.83
107	Heterochromia iridis	Enrichment	MITF	2.83
108	Tietz albinism-deafness syndrome	Enrichment	MITF	2.83
109	Accelerated tumor formation	Enrichment	MDM2	2.83
110	Lessel-kubisch syndrome	Enrichment	MDM2	2.83
111	Bone marrow failure syndrome 5	Enrichment	TP53	2.83
112	Papilloma of choroid plexus	Enrichment	TP53	2.83
113	Basal cell carcinoma 7	Enrichment	TP53	2.83
114	Anaplastic thyroid carcinoma	Enrichment	TP53	2.83
115	Coloboma, osteopetrosis, microphthalmia, macrocephaly, albinism, and deafness	Enrichment	MITF	2.83
116	Ductal carcinoma in situ	Enrichment	TP53	2.83
117	Patent ductus arteriosus 2	Enrichment	TFAP2B	2.83
118	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	2.83
119	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	2.83
120	Cdkn2a cancer predisposition	Enrichment	CDKN2A	2.83
121	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	2.83
122	Choroid plexus cancer	Enrichment	TP53	2.83
123	Pleomorphic xanthoastrocytoma	Enrichment	TP53	2.83
124	Familial isolated dilated cardiomyopathy	Enrichment	LMNA, TMPO	2.82
125	Combined oxidative phosphorylation deficiency 35	Enrichment	TRIT1	2.79
126	Immunodeficiency 33	Enrichment	IKBKG	2.75
127	Ectodermal dysplasia and immunodeficiency 2	Enrichment	NFKBIA	2.75
128	Immunodeficiency, common variable, 10	Enrichment	NFKB2	2.75
129	Autoinflammatory disease, familial, behcet-like 3	Enrichment	RELA	2.75
130	Rela fusion-positive ependymoma	Enrichment	RELA	2.75
131	Glucosephosphate dehydrogenase deficiency	Enrichment	IKBKG	2.75
132	Gastric cancer	Enrichment	CDKN2A, TP53	2.75
133	Aplasia cutis congenita	Enrichment	UBA2	2.73
134	Neurodevelopmental disorder with achalasia, polyneuropathy, and alacrima	Enrichment	NDC1	2.70
135	Atrial fibrillation, familial, 15	Enrichment	NUP155	2.70
136	Dystonia 37, early-onset, with striatal lesions	Enrichment	NUP54	2.70
137	Nephrotic syndrome, type 19	Enrichment	NUP160	2.70
138	Galloway-mowat syndrome 8	Enrichment	NUP133	2.70
139	Nephrotic syndrome, type 13	Enrichment	NUP205	2.70
140	Microcephaly 24, primary, autosomal recessive	Enrichment	NUP37	2.70
141	Galloway-mowat syndrome 7	Enrichment	NUP107	2.70
142	Nephrotic syndrome, type 12	Enrichment	NUP93	2.70
143	Nephrotic syndrome, type 11	Enrichment	NUP107	2.70
144	Sandestig-stefanova syndrome	Enrichment	NUP188	2.70
145	Ovarian dysgenesis 6	Enrichment	NUP107	2.70
146	Nephrotic syndrome, type 18	Enrichment	NUP133	2.70
147	Infection-induced acute-onset axonal neuropathy	Enrichment	RCC1	2.70
148	Diffuse large b-cell lymphoma	Enrichment	CREBBP, DNMT3A, TP53	2.70
149	Leukemia, acute myeloid	Enrichment	DNMT3A, NPM1, NUP214, TP53	2.70
150	Mitochondrial disease	Enrichment	TRIT1, TRMT10C	2.67
151	Cataract 46, juvenile-onset, with or without arrhythmic cardiomyopathy	Enrichment	LEMD2	2.66
152	Mandibuloacral dysplasia with type a lipodystrophy	Enrichment	LMNA	2.66
153	Myopathy, x-linked, with postural muscle atrophy	Enrichment	EMD	2.66
154	Heart-hand syndrome, slovenian type	Enrichment	LMNA	2.66
155	Charcot-marie-tooth disease, axonal, type 2b1	Enrichment	LMNA	2.66
156	Cardiomyopathy, dilated, with hypergonadotropic hypogonadism	Enrichment	LMNA	2.66
157	Cardiomyopathy, dilated, 1d	Enrichment	LMNA	2.66
158	Restrictive dermopathy 2	Enrichment	LMNA	2.66
159	Emery-dreifuss muscular dystrophy 3, autosomal recessive	Enrichment	LMNA	2.66
160	Cataract 46 juvenile-onset	Enrichment	LEMD2	2.66
161	Lipodystrophy, familial partial, type 1	Enrichment	LMNA	2.66
162	Osteopoikilosis	Enrichment	LEMD3	2.66
163	Autosomal dominant primary microcephaly	Enrichment	LMNB1	2.66
164	Familial partial lipodystrophy	Enrichment	LMNA	2.66
165	12q14 microdeletion syndrome	Enrichment	LEMD3	2.66
166	Charcot-marie-tooth disease type 2b1	Enrichment	LMNA	2.66
167	X-linked emery-dreifuss muscular dystrophy	Enrichment	EMD	2.66
168	Maturity-onset diabetes of the young, type 2	Enrichment	GCK	2.64
169	Fetal akinesia deformation sequence 4	Enrichment	NUP88	2.64
170	Hyperinsulinemic hypoglycemia, familial, 3	Enrichment	GCK	2.64
171	Fasting plasma glucose level quantitative trait locus 5	Enrichment	GCKR	2.64
172	Encephalopathy, acute, infection-induced 9	Enrichment	NUP214	2.64
173	Intellectual developmental disorder, autosomal recessive 79	Enrichment	TPR	2.64
174	Gestational diabetes	Enrichment	GCK	2.64
175	Familial acute necrotizing encephalopathy	Enrichment	RANBP2	2.64
176	Galloway-mowat syndrome 10	Enrichment	YRDC	2.61
177	Immunodeficiency-centromeric instability-facial anomalies syndrome 1	Enrichment	DNMT3B	2.60
178	Facioscapulohumeral muscular dystrophy 4, digenic	Enrichment	DNMT3B	2.60
179	Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant	Enrichment	DNMT1	2.60
180	Tatton-brown-rahman syndrome	Enrichment	DNMT3A	2.60
181	Autism 19	Enrichment	EIF4E	2.60
182	Goldberg-shprintzen syndrome	Enrichment	NEK9	2.59
183	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	2.58
184	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	2.58
185	Sporadic pheochromocytoma/secreting paraganglioma	Enrichment	DNMT3A, VHL	2.58
186	Torsion dystonia 1	Enrichment	EIF2AK2	2.58
187	Retinal hemangioblastoma	Enrichment	VHL	2.55
188	Hereditary breast carcinoma	Enrichment	BLM, BRCA1, ESR1, TP53	2.54
189	Hereditary breast ovarian cancer syndrome	Enrichment	MITF, TP53	2.53
190	Pontocerebellar hypoplasia, type 4	Enrichment	TSEN54	2.53
191	Methylmalonic aciduria and homocystinuria, cbld type	Enrichment	TSEN54	2.53
192	Melanoma-astrocytoma syndrome	Enrichment	CDKN2A	2.53
193	Adrenocortical carcinoma, hereditary	Enrichment	TP53	2.53
194	Cervical cancer	Enrichment	TP53	2.53
195	Premature ovarian failure 3	Enrichment	FOXL2	2.53
196	Melanoma, cutaneous malignant 2	Enrichment	CDKN2A	2.53
197	Lymphoma, hodgkin, classic	Enrichment	TP53	2.53
198	Melanoma, cutaneous malignant 8	Enrichment	MITF	2.53
199	Microcephaly and chorioretinopathy, autosomal recessive, 3	Enrichment	TP53BP1	2.53
200	Melanoma-pancreatic cancer syndrome	Enrichment	CDKN2A	2.53
201	Papillary renal cell carcinoma	Enrichment	MITF	2.53
202	Congenital fibrosarcoma	Enrichment	TP53	2.53
203	Li-fraumeni syndrome 1	Enrichment	TP53	2.53
204	Sarcoma	Enrichment	TP53	2.53
205	Cervix carcinoma	Enrichment	TP53	2.53
206	Hodgkin's lymphoma	Enrichment	TP53	2.53
207	Esotropia	Enrichment	TFAP2A	2.53
208	Microcephaly and chorioretinopathy 3	Enrichment	TP53BP1	2.53
209	Malignant granulosa cell tumor of the ovary	Enrichment	FOXL2	2.53
210	Lens subluxation	Enrichment	TFAP2A	2.53
211	Familial patent arterial duct	Enrichment	TFAP2B	2.53
212	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	2.53
213	Differentiated thyroid carcinoma	Enrichment	TPR, TRIM27	2.53
214	Neurodevelopmental disorder with microcephaly, hypotonia, nystagmus, and seizures	Enrichment	CPSF3	2.52
215	Myopathy, lactic acidosis, and sideroblastic anemia 1	Enrichment	PUS1	2.49
216	Perrault syndrome 2	Enrichment	PRORP	2.48
217	Restrictive dermopathy 1	Enrichment	LMNA	2.48
218	Myoglobinuria, acute recurrent, autosomal recessive	Enrichment	LPIN1	2.48
219	Lipodystrophy, familial partial, type 2	Enrichment	LMNA	2.48
220	Muscular dystrophy, congenital, lmna-related	Enrichment	LMNA	2.48
221	Restrictive dermopathy	Enrichment	LMNA	2.48
222	Intellectual developmental disorder, x-linked 9	Enrichment	FTSJ1	2.48
223	Microcephaly, short stature, and impaired glucose metabolism 1	Enrichment	TRMT10A	2.48
224	Intellectual developmental disorder, autosomal recessive 71	Enrichment	ALKBH8	2.48
225	Intellectual developmental disorder with abnormal behavior, microcephaly, and short stature	Enrichment	PUS7	2.48
226	Microcephaly, growth deficiency, seizures, and brain malformations	Enrichment	WDR4	2.48
227	Galloway-mowat syndrome 6	Enrichment	WDR4	2.48
228	Intellectual developmental disorder, autosomal recessive 68	Enrichment	TRMT1	2.48
229	Intellectual developmental disorder, autosomal recessive 82	Enrichment	NSUN6	2.48
230	Galloway-mowat syndrome 5	Enrichment	TPRKB	2.48
231	Microcephaly, facial dysmorphism, renal agenesis, and ambiguous genitalia syndrome	Enrichment	CTU2	2.48
232	Leukodystrophy, hypomyelinating, 15	Enrichment	EPRS1	2.48
233	Galloway-mowat syndrome 9	Enrichment	GON7	2.48
234	B-cell immunodeficiency, distal limb anomalies, and urogenital malformations	Enrichment	TOP2B	2.48
235	Ataxia-telangiectasia-like disorder 2	Enrichment	PCNA	2.48
236	Dilated cardiomyopathy	Enrichment	EMD, LMNA	2.46
237	Intellectual developmental disorder, autosomal dominant 74	Enrichment	HNRNPC	2.46
238	Immunodeficiency, common variable, 1	Enrichment	NFKB2	2.45
239	Autism spectrum disorder	Enrichment	DNMT3A, NR3C2, NR4A2, SATB2, SMC3, TOP2B	2.45
240	Amblyopia	Enrichment	TSEN54	2.43
241	Neuropathy, hereditary sensory, type ie	Enrichment	DNMT1	2.43
242	Nestor-guillermo progeria syndrome	Enrichment	BANF1	2.42
243	Neuronopathy, distal hereditary motor, autosomal recessive 10	Enrichment	VRK1	2.42
244	Microcephaly-complex motor and sensory axonal neuropathy syndrome	Enrichment	VRK1	2.42
245	Neurodevelopmental disorder with cerebellar atrophy and motor dysfunction	Enrichment	GEMIN5	2.41
246	Neurodevelopmental disorder with microcephaly, cataracts, and renal abnormalities	Enrichment	GEMIN4	2.41
247	Muscular dystrophy, limb-girdle, autosomal recessive 29	Enrichment	SNUPN	2.41
248	Striatonigral degeneration, infantile	Enrichment	NUP62	2.40
249	Nephronophthisis-like nephropathy 1	Enrichment	RANGAP1	2.40
250	Nephrotic syndrome, type 17	Enrichment	NUP85	2.40
251	Liver failure, infantile, transient	Enrichment	TRMU	2.39
252	Mitochondrial oxidative phosphorylation disorder	Enrichment	MTO1	2.39
253	Intellectual developmental disorder, x-linked 113	Enrichment	CSTF2	2.38
254	Anauxetic dysplasia 2	Enrichment	POP1	2.38
255	Pontocerebellar hypoplasia, type 10	Enrichment	CLP1	2.38
256	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	IKBKG	2.35
257	Lactic acidosis	Enrichment	PRORP	2.35
258	Hutchinson-gilford progeria syndrome	Enrichment	LMNA	2.35
259	Microtia-anotia	Enrichment	LMNA	2.35
260	Hereditary recurrent myoglobinuria	Enrichment	LPIN1	2.35
261	Sick sinus syndrome	Enrichment	LMNA	2.35
262	Waardenburg syndrome, type 2a	Enrichment	MITF	2.35
263	Osteogenic sarcoma	Enrichment	TP53	2.35
264	Miller-dieker lissencephaly syndrome	Enrichment	HIC1	2.35
265	Dedifferentiated liposarcoma	Enrichment	MDM2	2.35
266	Atypical teratoid rhabdoid tumor	Enrichment	TP53	2.35
267	Anaplastic astrocytoma	Enrichment	TP53	2.35
268	Squamous cell carcinoma	Enrichment	TP53	2.35
269	Adenocarcinoma	Enrichment	TP53	2.35
270	Bone osteosarcoma	Enrichment	TP53	2.35
271	Well-differentiated liposarcoma	Enrichment	MDM2	2.35
272	Maturity-onset diabetes of the young, type 1	Enrichment	GCK	2.34
273	Camptodactyly-arthropathy-coxa vara-pericarditis syndrome	Enrichment	TPR	2.34
274	Diabetes mellitus, permanent neonatal, 1	Enrichment	GCK	2.34
275	Bone marrow failure syndrome 2	Enrichment	GCK	2.34
276	Acute myeloid leukemia with t(6;9) (p23;q34.1)	Enrichment	NUP214	2.34
277	Acute necrotizing encephalopathy of childhood	Enrichment	RANBP2	2.34
278	Semilobar holoprosencephaly	Enrichment	SMC1A, STAG2	2.34
279	Difference of sex development	Enrichment	AR, NR5A1	2.32
280	Developmental delay with dysmorphic facies and dental anomalies	Enrichment	SATB1	2.28
281	Chromosome 2q37 deletion syndrome	Enrichment	HDAC4	2.28
282	Imagawa-matsumoto syndrome	Enrichment	SUZ12	2.28
283	Neurodevelopmental disorder with central hypotonia and dysmorphic facies	Enrichment	HDAC4	2.28
284	Den hoed-de boer-voisin syndrome	Enrichment	SATB1	2.28
285	Intellectual disability-acpilepsy-dental anomalies-facial dysmorphism syndrome	Enrichment	SATB1	2.28
286	Boomerang dysplasia	Enrichment	FLNB	2.27
287	Robin sequence with cleft mandible and limb anomalies	Enrichment	EIF4A3	2.27
288	Atelosteogenesis, type iii	Enrichment	FLNB	2.27
289	Atelosteogenesis, type i	Enrichment	FLNB	2.27
290	Parkinson disease 18, autosomal dominant	Enrichment	EIF4G1	2.27
291	Immunodeficiency 38 with basal ganglia calcification	Enrichment	ISG15	2.27
292	Encephalopathy, acute, infection-induced 7	Enrichment	IRF3	2.27
293	Oocyte/zygote/embryo maturation arrest 17	Enrichment	KPNA7	2.27
294	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	2.27
295	Immunodeficiency 31a	Enrichment	STAT1	2.27
296	Neurodevelopmental disorder with hypotonia and speech delay, with or without seizures	Enrichment	EIF4A2	2.27
297	Immunodeficiency 31b	Enrichment	STAT1	2.27
298	Singleton-merten syndrome 2	Enrichment	RIGI	2.27
299	Pseudo-torch syndrome 2	Enrichment	USP18	2.27
300	Spastic paraplegia 88, autosomal dominant	Enrichment	KPNA3	2.27
301	Flnb-related disorders	Enrichment	FLNB	2.27
302	Mendelian susceptibility to mycobacterial diseases due to partial jak1 deficiency	Enrichment	JAK1	2.27
303	Partial corpus callosum agenesis-cerebellar vermis hypoplasia with posterior fossa cysts syndrome	Enrichment	KPNA7	2.27
304	Primary autosomal recessive microcephaly	Enrichment	NUP37, PHC1	2.26
305	Cataract 6, multiple types	Enrichment	LEMD2	2.26
306	Autosomal recessive limb-girdle muscular dystrophy type 2b	Enrichment	LMNA	2.26
307	Histiocytoid hemangioma	Enrichment	LMNA	2.26
308	Acute leukemia of ambiguous lineage	Enrichment	VHL	2.25
309	Palmoplantar keratoderma, punctate type ii	Enrichment	BRCA1	2.25
310	Bloom syndrome	Enrichment	BLM	2.25
311	Developmental and epileptic encephalopathy 85 with or without midline brain defects	Enrichment	SMC1A	2.25
312	Holoprosencephaly 13, x-linked	Enrichment	STAG2	2.25
313	Cornelia de lange syndrome 3 with or without midline brain defects	Enrichment	SMC3	2.25
314	Seckel syndrome 10	Enrichment	NSMCE2	2.25
315	Cornelia de lange syndrome 4 with or without midline brain defects	Enrichment	RAD21	2.25
316	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 6	Enrichment	RPA1	2.25
317	Mullegama-klein-martinez syndrome	Enrichment	STAG2	2.25
318	Infant-type hemispheric glioma	Enrichment	BRCA1	2.25
319	Riddle syndrome	Enrichment	RNF168	2.25
320	Intellectual developmental disorder, autosomal dominant 47	Enrichment	STAG1	2.25
321	Mungan syndrome	Enrichment	RAD21	2.25
322	Intellectual developmental disorder, autosomal recessive 38	Enrichment	HERC2	2.25
323	Xq25 microduplication syndrome	Enrichment	STAG2	2.25
324	Atelis syndrome 2	Enrichment	SMC5	2.25
325	Primary peritoneal carcinoma	Enrichment	BRCA1	2.25
326	Perrault syndrome 1	Enrichment	PRORP	2.23
327	Branchiooculofacial syndrome	Enrichment	TFAP2A	2.23
328	Small cell cancer of the lung	Enrichment	TP53	2.23
329	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	2.23
330	Blepharophimosis	Enrichment	FOXL2	2.23
331	Lung sarcomatoid carcinoma	Enrichment	TP53	2.23
332	Embryonal rhabdomyosarcoma	Enrichment	TP53	2.23
333	Autosomal recessive chorioretinopathy-microcephaly syndrome	Enrichment	TP53BP1	2.23
334	Clear cell papillary renal cell carcinoma	Enrichment	MITF	2.23
335	Neurodevelopmental disorder with hypotonia, microcephaly, and seizures	Enrichment	CPSF3	2.22
336	Myopia 27, autosomal dominant	Enrichment	CPSF1	2.22
337	Chronic eosinophilic leukemia	Enrichment	FIP1L1	2.22
338	Primary hyperaldosteronism	Enrichment	NR3C1, TP53	2.21
339	Common variable immunodeficiency	Enrichment	NFKB2	2.21
340	Endometrial cancer	Enrichment	BLM, BRCA1	2.21
341	Myeloproliferative neoplasm	Enrichment	DNMT3A	2.20
342	Glioblastoma	Enrichment	DNMT3A	2.20
343	Emery-dreifuss muscular dystrophy 2, autosomal dominant	Enrichment	LMNA	2.18
344	Galloway-mowat syndrome 2, x-linked	Enrichment	LAGE3	2.18
345	Intellectual developmental disorder, autosomal recessive 5	Enrichment	NSUN2	2.18
346	Dubowitz syndrome	Enrichment	NSUN2	2.18
347	Hydrolethalus syndrome 1	Enrichment	PUS3	2.18
348	Neurodevelopmental disorder with brain abnormalities, poor growth, and dysmorphic facies	Enrichment	ADAT3	2.18
349	Neurodevelopmental disorder with microcephaly and gray sclerae	Enrichment	PUS3	2.18
350	Spinocerebellar ataxia, autosomal recessive 28	Enrichment	THG1L	2.18
351	Galloway-mowat syndrome 3	Enrichment	OSGEP	2.18
352	Primary microcephaly-mild intellectual disability-young-onset diabetes syndrome	Enrichment	TRMT10A	2.18
353	Prostate cancer	Enrichment	AR, BRCA1, TP53	2.17
354	Nijmegen breakage syndrome	Enrichment	GCK	2.16
355	Ectodermal dysplasia 11b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	RANBP2	2.16
356	Rhabdomyosarcoma 2	Enrichment	TP53	2.13
357	Lymphoma	Enrichment	TP53	2.13
358	Acute megakaryocytic leukemia	Enrichment	TP53	2.13
359	Precursor t-cell acute lymphoblastic leukemia	Enrichment	CDKN2A, NUP214	2.13
360	Facioscapulohumeral muscular dystrophy 1	Enrichment	DNMT3B	2.13
361	Immunodeficiency-centromeric instability-facial anomalies syndrome	Enrichment	DNMT3B	2.13
362	Pontocerebellar hypoplasia, type 1a	Enrichment	VRK1	2.12
363	Congenital pontocerebellar hypoplasia type 1	Enrichment	VRK1	2.12
364	Bethlem myopathy 1a	Enrichment	LMNA	2.11
365	Cerebrocostomandibular syndrome	Enrichment	SNRPB	2.11
366	Hypotrichosis 11	Enrichment	SNRPE	2.11
367	Coronary heart disease 5	Enrichment	IKBKG	2.10
368	Mitochondrial myopathy with reversible cytochrome c oxidase deficiency	Enrichment	TRMU	2.09
369	Rare mitochondrial non-syndromic sensorineural deafness	Enrichment	TRMU	2.09
370	Myasthenic syndrome, congenital, 6, presynaptic	Enrichment	VHL	2.08
371	Primary polycythemia	Enrichment	VHL	2.08
372	Hereditary sensory and autonomic neuropathy type 1	Enrichment	DNMT1	2.06
373	Congenital muscular dystrophy	Enrichment	LMNA	2.05
374	Myocarditis	Enrichment	LMNA	2.05
375	Branchiootorenal syndrome 1	Enrichment	TFAP2A	2.05
376	Waardenburg syndrome, type 4a	Enrichment	MITF	2.05
377	Intestinal pseudo-obstruction	Enrichment	TFAP2B	2.05
378	Breast adenocarcinoma	Enrichment	TP53	2.05
379	Lung squamous cell carcinoma	Enrichment	CDKN2A	2.05
380	Waardenburg syndrome	Enrichment	MITF	2.05
381	Ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	RANBP2	2.04
382	Achalasia-addisonianism-alacrima syndrome	Enrichment	AAAS	2.04
383	Maturity-onset diabetes of the young, type 3	Enrichment	GCK	2.04
384	Ectodermal dysplasia	Enrichment	RANBP2	2.04
385	Orofaciodigital syndrome vi	Enrichment	TOPORS	2.01
386	Arrhythmogenic right ventricular dysplasia, familial, 9	Enrichment	LMNA	2.00
387	Galloway-mowat syndrome 4	Enrichment	TP53RK	2.00
388	Hydrolethalus syndrome	Enrichment	PUS3	2.00
389	Esophageal cancer	Enrichment	TP53	1.99
390	Waardenburg syndrome, type 1	Enrichment	MITF	1.99
391	Squamous cell carcinoma, head and neck	Enrichment	TP53	1.99
392	Waardenburg syndrome, type 2e	Enrichment	MITF	1.99
393	Branchiootorenal syndrome	Enrichment	TFAP2A	1.99
394	Essential thrombocythemia	Enrichment	TP53	1.99
395	Gallbladder cancer	Enrichment	TP53	1.99
396	Hyperaldosteronism, familial, type ii	Enrichment	SATB1	1.98
397	Snijders blok-campeau syndrome	Enrichment	CHD3	1.98
398	Immunodeficiency 31c	Enrichment	STAT1	1.97
399	Spastic paraplegia 37, autosomal dominant	Enrichment	KPNA3	1.97
400	Autoinflammation, immune dysregulation, and eosinophilia	Enrichment	JAK1	1.97
401	Singleton-merten syndrome	Enrichment	RIGI	1.97
402	Submucosal cleft palate	Enrichment	UBB	1.97
403	Cleft hard palate	Enrichment	UBB	1.97
404	46 xx gonadal dysgenesis	Enrichment	NR5A1, NUP107	1.96
405	Erythrocytosis, familial, 2	Enrichment	VHL	1.95
406	Skin/hair/eye pigmentation, variation in, 1	Enrichment	HERC2	1.95
407	Xeroderma pigmentosum, complementation group c	Enrichment	XPC	1.95
408	Cornelia de lange syndrome 2	Enrichment	SMC1A	1.95
409	Lig4 syndrome	Enrichment	XRCC4	1.95
410	Lung disease, immunodeficiency, and chromosome breakage syndrome	Enrichment	NSMCE3	1.95
411	Xeroderma pigmentosum, complementation group a	Enrichment	XPC	1.95
412	Fanconi anemia, complementation group s	Enrichment	BRCA1	1.95
413	Werner syndrome	Enrichment	WRN	1.95
414	Pancreatic cancer 4	Enrichment	BRCA1	1.95
415	Short stature, microcephaly, and endocrine dysfunction	Enrichment	XRCC4	1.95
416	Inflammatory breast carcinoma	Enrichment	BRCA1	1.95
417	Xeroderma pigmentosum group c	Enrichment	XPC	1.95
418	Peritoneum cancer	Enrichment	BRCA1	1.95
419	Bilateral breast cancer	Enrichment	BRCA1	1.95
420	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	RANBP2	1.94
421	Autosomal recessive hypohidrotic ectodermal dysplasia syndrome	Enrichment	RANBP2	1.94
422	Pontocerebellar hypoplasia, type 1b	Enrichment	VRK1	1.94
423	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	TSEN54	1.93
424	Isolated congenital microcephaly	Enrichment	TSEN15	1.93
425	Glioma susceptibility 1	Enrichment	TP53	1.93
426	Lymphoma, non-hodgkin, familial	Enrichment	TP53	1.93
427	Autosomal recessive non-syndromic intellectual disability	Enrichment	ALKBH8, NSUN2, TPR	1.93
428	Cardiac conduction defect	Enrichment	LMNA	1.88
429	Muscular dystrophy, limb-girdle, autosomal recessive 2	Enrichment	LMNA	1.88
430	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	LMNA	1.88
431	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	LMNA	1.88
432	Adult hepatocellular carcinoma	Enrichment	TP53	1.88
433	Phenylketonuria	Enrichment	NSUN2	1.88
434	Anencephaly	Enrichment	PUS3	1.88
435	Prostate cancer, hereditary, x-linked 3	Enrichment	AR	1.87
436	Androgen insensitivity, partial	Enrichment	AR	1.87
437	Glucocorticoid resistance, generalized	Enrichment	NR3C1	1.87
438	46,xx sex reversal 4	Enrichment	NR5A1	1.87
439	Spermatogenic failure 8	Enrichment	NR5A1	1.87
440	Progesterone resistance	Enrichment	PGR	1.87
441	Hypertension, early-onset, autosomal dominant, with severe exacerbation in pregnancy	Enrichment	NR3C2	1.87
442	Parkinson disease 7, autosomal recessive early-onset	Enrichment	PARK7	1.87
443	Premature ovarian failure 7	Enrichment	NR5A1	1.87
444	Cholestasis, progressive familial intrahepatic, 5	Enrichment	NR1H4	1.87
445	Congenital anomalies of kidney and urinary tract 3	Enrichment	NRIP1	1.87
446	Menke-hennekam syndrome 1	Enrichment	CREBBP	1.87
447	Intellectual developmental disorder with language impairment and early-onset dopa-responsive dystonia-parkinsonism	Enrichment	NR4A2	1.87
448	Pparg-associated congenital generalized lipodystrophy	Enrichment	PPARG	1.87
449	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	1.87
450	Rickets	Enrichment	VDR	1.87
451	Chromosome 15q24 deletion syndrome	Enrichment	SIN3A	1.87
452	Pseudohyperaldosteronism type 2	Enrichment	NR3C2	1.87
453	Resistance to thyroid hormone due to a mutation in thyroid hormone receptor alpha	Enrichment	THRA	1.87
454	Acute myeloid leukemia with multilineage dysplasia	Enrichment	NPM1	1.87
455	Acute myeloid leukemia with npm1 somatic mutations	Enrichment	NPM1	1.87
456	Wilms tumor 7	Enrichment	TRIM28	1.87
457	Complete androgen insensitivity syndrome	Enrichment	AR	1.87
458	Menke-hennekam syndrome	Enrichment	CREBBP	1.87
459	Resistance to thyroid hormone due to a mutation in thyroid hormone receptor beta	Enrichment	THRB	1.87
460	Generalized resistance to thyroid hormone	Enrichment	THRB	1.87
461	Hyperinsulinemic hypoglycemia, familial, 1	Enrichment	GCK	1.87
462	Inflammatory myofibroblastic tumor	Enrichment	RANBP2	1.87
463	Nonsyndromic genetic hyperinsulinism	Enrichment	GCK	1.87
464	Specific learning disability	Enrichment	DNMT3A	1.86
465	Fanconi anemia, complementation group d2	Enrichment	VHL	1.86
466	Von hippel-lindau syndrome	Enrichment	VHL	1.86
467	Cat eye syndrome	Enrichment	TFAP2A	1.83
468	Leukemia, chronic lymphocytic	Enrichment	TP53	1.83
469	Familial colorectal cancer	Enrichment	TP53	1.83
470	Primary hypereosinophilic syndrome	Enrichment	FIP1L1	1.82
471	Charcot-marie-tooth hereditary neuropathy	Enrichment	VRK1	1.82
472	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	LMNA	1.81
473	Weaver syndrome	Enrichment	SUZ12	1.81
474	Glass syndrome	Enrichment	SATB2	1.81
475	Mitochondrial dna depletion syndrome 4a	Enrichment	RANBP2	1.80
476	Larsen syndrome	Enrichment	FLNB	1.79
477	Uvula, bifid	Enrichment	UBB	1.79
478	Spondylocarpotarsal synostosis syndrome	Enrichment	FLNB	1.79
479	Cleft soft palate	Enrichment	UBB	1.79
480	Heparin cofactor ii deficiency	Enrichment	EIF4G3	1.79
481	Breast implant-associated anaplastic large cell lymphoma	Enrichment	JAK1	1.79
482	Leukemia, acute lymphoblastic	Enrichment	CDKN2A	1.79
483	Myelodysplastic syndrome	Enrichment	TP53	1.79
484	Pervasive developmental disorder	Enrichment	PUS7	1.78
485	Polyhydramnios	Enrichment	PUS3	1.78
486	Rare pervasive developmental disorder	Enrichment	PUS7	1.78
487	Anauxetic dysplasia 1	Enrichment	POP1	1.78
488	Pituitary stalk interruption syndrome	Enrichment	DNMT1	1.76
489	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	LMNA	1.76
490	Epicanthus	Enrichment	TFAP2A	1.76
491	Mitochondrial dna depletion syndrome 4b	Enrichment	RANBP2	1.74
492	Permanent neonatal diabetes mellitus	Enrichment	GCK	1.74
493	Microcephaly	Enrichment	CTU2, NUP188, PRORP, TSEN54	1.74
494	Breast cancer	Enrichment	BLM, BRCA1, ESR1, TP53	1.73
495	Cardiomyopathy, dilated, 1e	Enrichment	LMNA	1.73
496	Cataract 44	Enrichment	LEMD2	1.73
497	Rhabdomyosarcoma	Enrichment	BRCA1, TP53	1.72
498	Renal cell carcinoma, papillary, 1	Enrichment	VHL	1.71
499	Multiple enchondromatosis, maffucci type	Enrichment	VHL	1.71
500	Autosomal recessive intellectual developmental disorder	Enrichment	NSUN2	1.70
501	Malaria	Enrichment	IKBKG	1.70
502	Lung cancer susceptibility 3	Enrichment	TP53	1.69
503	Arteriovenous malformations of the brain	Enrichment	LEMD3	1.68
504	2p21 microdeletion syndrome	Enrichment	PPM1B	1.67
505	Trichorhinophalangeal syndrome, type ii	Enrichment	RAD21	1.65
506	Polyposis syndrome, hereditary mixed, 1	Enrichment	BRCA1	1.65
507	Cholangiocarcinoma	Enrichment	BRCA1	1.65
508	Pontocerebellar hypoplasia, type 1e	Enrichment	VRK1	1.64
509	Cardiomyopathy, dilated, 1a	Enrichment	LMNA	1.64
510	Pierre robin syndrome	Enrichment	SNRPB	1.63
511	Diabetes mellitus	Enrichment	GCK	1.60
512	Endometrial stromal sarcoma	Enrichment	SUZ12	1.59
513	Cardiomyopathy, familial hypertrophic, 1	Enrichment	LMNA	1.58
514	Autoinflammatory disease	Enrichment	LPIN2	1.58
515	Muscular dystrophy	Enrichment	LMNA	1.58
516	Amyotrophic lateral sclerosis-parkinsonism/dementia complex 1	Enrichment	PARK7	1.57
517	Thyroid hormone resistance, selective pituitary	Enrichment	THRB	1.57
518	Galactosemia ii	Enrichment	NR3C1	1.57
519	Thyroid hormone resistance, generalized, autosomal dominant	Enrichment	THRB	1.57
520	Thumb deformity	Enrichment	CREBBP	1.57
521	Spinal and bulbar muscular atrophy, x-linked 1	Enrichment	AR	1.57
522	Carotid intimal medial thickness 1	Enrichment	PPARG	1.57
523	Thyroid hormone resistance, generalized, autosomal recessive	Enrichment	THRB	1.57
524	Pseudohypoaldosteronism, type i, autosomal dominant	Enrichment	NR3C2	1.57
525	Hypothyroidism, congenital, nongoitrous, 6	Enrichment	THRA	1.57
526	Hypotonia, ataxia, developmental delay, and tooth enamel defect syndrome	Enrichment	CTBP1	1.57
527	46,xy sex reversal 1	Enrichment	AR	1.57
528	Androgen insensitivity syndrome	Enrichment	AR	1.57
529	Immunodeficiency 66	Enrichment	MRTFA	1.57
530	Menke-hennekam syndrome 2	Enrichment	EP300	1.57
531	Thyroid hormone resistance syndrome	Enrichment	THRB	1.57
532	Hypospadias 1, x-linked	Enrichment	AR	1.57
533	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	1.57
534	46,xy sex reversal 3	Enrichment	NR5A1	1.57
535	Witteveen-kolk syndrome	Enrichment	SIN3A	1.57
536	Intellectual developmental disorder with or without epilepsy or cerebellar ataxia	Enrichment	RORA	1.57
537	Acute myeloid leukemia without maturation	Enrichment	NPM1	1.57
538	Lymphomatoid papulosis	Enrichment	NPM1	1.57
539	Posterior hypospadias	Enrichment	AR	1.57
540	Developmental delay-language impairment-dopa responsive dystonia-parkinsonism syndrome due to 2q24 microdeletion	Enrichment	NR4A2	1.57
541	Pseudohypoaldosteronism	Enrichment	NR3C2	1.57
542	Primary cutaneous anaplastic large cell lymphoma	Enrichment	NPM1	1.57
543	Megakaryoblastic acute myeloid leukemia with t(1;22)(p13;q13)	Enrichment	MRTFA	1.57
544	Seckel syndrome	Enrichment	NUP85	1.56
545	Breast-ovarian cancer, familial 2	Enrichment	BRCA1	1.55
546	Brugada syndrome	Enrichment	LMNA	1.55
547	Craniosynostosis	Enrichment	TFAP2B	1.54
548	Hepatoblastoma	Enrichment	TP53	1.52
549	Chronic mucocutaneous candidiasis	Enrichment	STAT1	1.50
550	Hepatocellular carcinoma	Enrichment	TP53	1.50
551	Microphthalmia	Enrichment	TFAP2A	1.50
552	Diamond-blackfan anemia 1	Enrichment	TP53	1.48
553	Long qt syndrome	Enrichment	LMNA	1.47
554	Juvenile amyotrophic lateral sclerosis	Enrichment	VRK1	1.47
555	Hypotrichosis simplex	Enrichment	SNRPE	1.46
556	Ear malformation	Enrichment	MITF	1.46
557	Peripheral nervous system disease	Enrichment	LMNA	1.46
558	Neuropathy	Enrichment	LMNA	1.46
559	Left ventricular noncompaction	Enrichment	LMNA	1.42
560	Pheochromocytoma	Enrichment	VHL	1.41
561	Prader-willi syndrome	Enrichment	HERC2	1.41
562	Focal segmental glomerulosclerosis	Enrichment	NUP93	1.41
563	46,xx sex reversal 1	Enrichment	NR5A1	1.40
564	Estrogen resistance	Enrichment	ESR1	1.40
565	Tethered spinal cord syndrome	Enrichment	CREBBP	1.40
566	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.40
567	Migraine without aura	Enrichment	ESR1	1.40
568	Gtp cyclohydrolase 1-deficient dopa-responsive dystonia	Enrichment	NR4A2	1.40
569	Renal cell carcinoma, nonpapillary	Enrichment	VHL	1.38
570	Nk-cell enteropathy	Enrichment	AURKB	1.37
571	Myopathy	Enrichment	EMD	1.36
572	Charcot-marie-tooth disease	Enrichment	LMNA	1.35
573	Isolated growth hormone deficiency, type ia	Enrichment	XRCC4	1.35
574	Rett syndrome, congenital variant	Enrichment	SMC1A	1.35
575	Maturity-onset diabetes of the young	Enrichment	GCK	1.35
576	Familial atrial fibrillation	Enrichment	NUP155	1.33
577	Nephronophthisis	Enrichment	PIAS1	1.32
578	Diamond-blackfan anemia	Enrichment	TP53	1.29
579	Non-syndromic genetic deafness	Enrichment	MITF	1.29
580	Lipodystrophy, familial partial, type 3	Enrichment	PPARG	1.28
581	Spermatogenic failure 1	Enrichment	NR5A1	1.28
582	Leptin deficiency or dysfunction	Enrichment	PPARG	1.28
583	Congenital generalized lipodystrophy	Enrichment	PPARG	1.28
584	Arthrogryposis multiplex congenita 3, myogenic type	Enrichment	ESR1	1.28
585	Intrahepatic cholestasis of pregnancy	Enrichment	NR1H4	1.28
586	Dandy-walker syndrome	Enrichment	PUS3	1.26
587	Congenital nervous system abnormality	Enrichment	AAAS, CREBBP, DNMT3A, SMC1A	1.26
588	Nervous system disease	Enrichment	AAAS, CREBBP, DNMT3A, SMC1A	1.26
589	Hirschsprung disease 1	Enrichment	NUP98	1.25
590	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	VHL	1.24
591	Nonsyndromic hearing loss	Enrichment	MITF	1.22
592	Xeroderma pigmentosum, variant type	Enrichment	XPC	1.22
593	Uterine corpus cancer	Enrichment	BRCA1	1.22
594	Body mass index quantitative trait locus 11	Enrichment	DNMT3A	1.22
595	Spastic ataxia	Enrichment	DNMT1	1.19
596	Vitamin d-dependent rickets, type 2a	Enrichment	VDR	1.18
597	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.18
598	Acute myeloid leukemia with maturation	Enrichment	NPM1	1.18
599	Nonsyndromic 46,xx testicular disorders/differences of sex development	Enrichment	NR5A1	1.18
600	Breast-ovarian cancer, familial 1	Enrichment	BRCA1	1.15
601	Hypertelorism	Enrichment	TFAP2A	1.13
602	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	MITF	1.13
603	Medulloblastoma	Enrichment	WRN	1.12
604	Periventricular nodular heterotopia	Enrichment	BRCA1	1.12
605	Cataract	Enrichment	WRN	1.12
606	Male infertility	Enrichment	AR, NR5A1	1.12
607	Wolf-hirschhorn syndrome	Enrichment	CTBP1	1.11
608	Cholestasis, progressive familial intrahepatic, 1	Enrichment	NR1H4	1.11
609	Wilms tumor 5	Enrichment	TRIM28	1.11
610	Parkinson disease 6, autosomal recessive early-onset	Enrichment	PARK7	1.11
611	Hypertrichosis	Enrichment	CREBBP	1.11
612	46,xy disorder of sex development	Enrichment	NR5A1	1.11
613	Fanconi anemia, complementation group a	Enrichment	BRCA1, VHL	1.09
614	Fetal akinesia deformation sequence 1	Enrichment	NUP88	1.09
615	Nephrotic syndrome	Enrichment	NUP93	1.08
616	Cleft palate, isolated	Enrichment	SATB2	1.07
617	Type 2 diabetes mellitus	Enrichment	GCK	1.04
618	Alobar holoprosencephaly	Enrichment	STAG2	1.03
619	Hereditary retinal dystrophy	Enrichment	TRNT1	0.99
620	Fundus dystrophy	Enrichment	TRNT1	0.99
621	Cakut	Enrichment	CTU2	0.97
622	Rare genetic deafness	Enrichment	MITF	0.96
623	Multisystem inflammatory syndrome in children	Enrichment	IRF3	0.95
624	Non-syndromic x-linked intellectual disability	Enrichment	FTSJ1	0.95
625	Charge syndrome	Enrichment	EP300	0.94
626	Parkinson disease, late-onset	Enrichment	EIF4G1	0.92
627	Migraine with or without aura 1	Enrichment	ESR1	0.86
628	Early-onset parkinson's disease	Enrichment	PARK7	0.82
629	Connective tissue disease	Enrichment	FLNB	0.80
630	Pulmonary disease, chronic obstructive	Enrichment	VDR	0.79
631	Lung cancer	Enrichment	BRCA1	0.78
632	Dystonia	Enrichment	SATB2	0.77
633	Retinitis pigmentosa	Enrichment	TOPORS	0.76
634	Multiple sclerosis	Enrichment	NR1H3	0.76
635	Heart disease	Enrichment	CREBBP	0.76
636	46,xy partial gonadal dysgenesis	Enrichment	NR5A1	0.76
637	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	AR, NR5A1	0.76
638	Polydactyly, postaxial, type a1	Enrichment	EP300	0.73
639	Wilms tumor 1	Enrichment	TRIM28	0.73
640	Corpus callosum, agenesis of	Enrichment	CREBBP	0.73
641	Isolated corpus callosum agenesis	Enrichment	CREBBP	0.73
642	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP	0.73
643	Parkinson's disease	Enrichment	NR4A2	0.64
644	Dyskeratosis congenita	Enrichment	NPM1	0.64
645	Myocardial infarction	Enrichment	ESR1	0.59
646	Scoliosis	Enrichment	CREBBP	0.56
647	Epilepsy	Enrichment	NR4A2	0.38
648	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	PPARGC1A	0.26
649	Primary ovarian insufficiency	Enrichment	NR5A2	0.26
650	Autism	Enrichment	CREBBP	0.20

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Transport of the SLBP independent Mature mRNA

Pathway Network for Transport of the SLBP independent Mature mRNA

Pathway network for the Transport of the SLBP independent Mature mRNA SuperPath

Member Pathways for Transport of the SLBP independent Mature mRNA

Pathways in the Transport of the SLBP independent Mature mRNA SuperPath

Associated Genes for Transport of the SLBP independent Mature mRNA

Associated Disorders for Transport of the SLBP independent Mature mRNA

Disorders associated with Transport of the SLBP independent Mature mRNA SuperPath

STRING Interaction Network for Transport of the SLBP independent Mature mRNA

Sources for Transport of the SLBP independent Mature mRNA