Triglyceride metabolism

Pathway network for the Triglyceride metabolism SuperPath

Sources:

Reactome

Pathways in the Triglyceride metabolism SuperPath

#	Name	Source	Genes
1	Triglyceride metabolism	Reactome	ABHD5 AGMO CAV1 DGAT1 DGAT2 FABP1 FABP12 FABP2 FABP3 FABP4 FABP5 FABP6 FABP7 FABP9 GK GK2 GK3 GPAM GPAT2 GPD2 LIPE LPIN1 LPIN2 LPIN3 MGLL MOGAT1 MOGAT2 MOGAT3 PLIN1 PLIN3 PNPLA4 PNPLA5 PPP1CA PPP1CB PPP1CC PRKACA PRKACB PRKACG (see all 38) (see less)
2	Triglyceride catabolism	Reactome	ABHD5 CAV1 FABP1 FABP12 FABP2 FABP3 FABP4 FABP5 FABP6 FABP7 FABP9 GPD2 LIPE MGLL PLIN1 PLIN3 PNPLA4 PNPLA5 PPP1CA PPP1CB PPP1CC PRKACA PRKACB PRKACG (see all 24) (see less)
3	Triglyceride biosynthesis	Reactome	AGMO DGAT1 DGAT2 GK GK2 GK3 GPAM GPAT2 LPIN1 LPIN2 LPIN3 MOGAT1 MOGAT2 MOGAT3 (see all 14) (see less)

Gene overlap in member pathways for Triglyceride metabolism SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PLIN3	Perilipin 3	Protein Coding	2
2	MGLL	Monoglyceride Lipase	Protein Coding	2
3	MOGAT1	Monoacylglycerol O-Acyltransferase 1	Protein Coding	2
4	PNPLA5	Patatin Like Domain 5, Triacylglycerol Lipase	Protein Coding	2
5	GPAT2	Glycerol-3-Phosphate Acyltransferase 2, Mitochondrial	Protein Coding	2
6	FABP4	Fatty Acid Binding Protein 4	Protein Coding	2
7	FABP1	Fatty Acid Binding Protein 1	Protein Coding	2
8	FABP2	Fatty Acid Binding Protein 2	Protein Coding	2
9	FABP3	Fatty Acid Binding Protein 3	Protein Coding	2
10	FABP5	Fatty Acid Binding Protein 5	Protein Coding	2
11	FABP6	Fatty Acid Binding Protein 6	Protein Coding	2
12	FABP7	Fatty Acid Binding Protein 7	Protein Coding	2
13	LPIN1	Lipin 1	Protein Coding	2
14	GK	Glycerol Kinase	Protein Coding	2
15	GK2	Glycerol Kinase 2	Protein Coding	2
16	GK3	Glycerol Kinase 3	Protein Coding	2
17	GPD2	Glycerol-3-Phosphate Dehydrogenase 2	Protein Coding	2
18	MOGAT3	Monoacylglycerol O-Acyltransferase 3	Protein Coding	2
19	AGMO	Alkylglycerol Monooxygenase	Protein Coding	2
20	LIPE	Lipase E, Hormone Sensitive Type	Protein Coding	2
21	ABHD5	Abhydrolase Domain Containing 5, Lysophosphatidic Acid Acyltransferase	Protein Coding	2
22	PLIN1	Perilipin 1	Protein Coding	2
23	PPP1CA	Protein Phosphatase 1 Catalytic Subunit Alpha	Protein Coding	2
24	PPP1CB	Protein Phosphatase 1 Catalytic Subunit Beta	Protein Coding	2
25	PPP1CC	Protein Phosphatase 1 Catalytic Subunit Gamma	Protein Coding	2
26	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	2
27	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	2
28	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	2
29	GPAM	Glycerol-3-Phosphate Acyltransferase, Mitochondrial	Protein Coding	2
30	FABP9	Fatty Acid Binding Protein 9	Protein Coding	2
31	FABP12	Fatty Acid Binding Protein 12	Protein Coding	2
32	LPIN3	Lipin 3	Protein Coding	2
33	MOGAT2	Monoacylglycerol O-Acyltransferase 2	Protein Coding	2
34	PNPLA4	Patatin Like Domain 4, Phospholipase And Triacylglycerol Lipase	Protein Coding	2
35	DGAT2	Diacylglycerol O-Acyltransferase 2	Protein Coding	2
36	CAV1	Caveolin 1	Protein Coding	2
37	DGAT1	Diacylglycerol O-Acyltransferase 1	Protein Coding	2
38	LPIN2	Lipin 2	Protein Coding	2

Disorders associated with Triglyceride metabolism SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	3.97
2	Majeed syndrome	Enrichment	LPIN2	2.99
3	Autosomal dominant charcot-marie-tooth disease type 2 due to dgat2 mutation	Enrichment	DGAT2	2.99
4	Lipodystrophy, congenital generalized, type 3	Enrichment	CAV1	2.75
5	Pulmonary hypertension, primary, 3	Enrichment	CAV1	2.75
6	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	2.75
7	Lipodystrophy, familial partial, type 7	Enrichment	CAV1	2.75
8	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	2.75
9	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	2.75
10	Noonan syndrome-like disorder with loose anagen hair 2	Enrichment	PPP1CB	2.75
11	Glycerol kinase deficiency	Enrichment	GK	2.69
12	Myoglobinuria, acute recurrent, autosomal recessive	Enrichment	LPIN1	2.51
13	Chanarin-dorfman syndrome	Enrichment	ABHD5	2.45
14	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	2.45
15	Noonan syndrome-like disorder with loose anagen hair	Enrichment	PPP1CB	2.45
16	Fibrolamellar carcinoma	Enrichment	PRKACA	2.45
17	Diarrhea 7, protein-losing enteropathy type	Enrichment	DGAT1	2.38
18	Hereditary recurrent myoglobinuria	Enrichment	LPIN1	2.38
19	Congenital diarrhea 7 with exudative enteropathy	Enrichment	DGAT1	2.29
20	Lipodystrophy, familial partial, type 6	Enrichment	LIPE	2.28
21	Lipodystrophy, familial partial, type 4	Enrichment	PLIN1	2.28
22	Diarrhea	Enrichment	DGAT1	2.21
23	Diffuse cutaneous systemic sclerosis	Enrichment	CAV1	2.05
24	Limited scleroderma	Enrichment	CAV1	1.98
25	Heritable pulmonary arterial hypertension	Enrichment	CAV1	1.71
26	Autoinflammatory disease	Enrichment	LPIN2	1.61
27	Dandy-walker syndrome	Enrichment	PPP1CB	1.53
28	Male infertility	Enrichment	GPAT2	1.46
29	Noonan syndrome 1	Enrichment	PPP1CB	1.40
30	Rasopathy	Enrichment	PPP1CB	1.35
31	Type 2 diabetes mellitus	Enrichment	GPD2	1.14

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Triglyceride metabolism

Pathway Network for Triglyceride metabolism

Pathway network for the Triglyceride metabolism SuperPath

Member Pathways for Triglyceride metabolism

Pathways in the Triglyceride metabolism SuperPath

Gene overlap in member pathways for Triglyceride metabolism SuperPath

Associated Genes for Triglyceride metabolism

Associated Disorders for Triglyceride metabolism

Disorders associated with Triglyceride metabolism SuperPath

STRING Interaction Network for Triglyceride metabolism

Sources for Triglyceride metabolism