Type 2 papillary renal cell carcinoma

No Pathway Network information available for Type 2 papillary renal cell carcinoma

Pathways in the Type 2 papillary renal cell carcinoma SuperPath

#	Name	Source	Genes
1	Type 2 papillary renal cell carcinoma	WikiPathways	ARNT ARNT2 BIRC7 CADM2 CDKN1A COL21A1 CREBBP CTSK CUL2 DIAPH1 DVL2 EGLN1 EGLN2 EGLN3 ELOB ELOC EP300 EPAS1 FH HIF1A PDGFB PRCC RBX1 SETD2 SFPQ SLC2A1 TFE3 TFEB TGFA TGFB1 TGFB2 TGFB3 VEGFA VHL (see all 34) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RBX1	Ring-Box 1	Protein Coding	1
2	ARNT2	Aryl Hydrocarbon Receptor Nuclear Translocator 2	Protein Coding	1
3	CUL2	Cullin 2	Protein Coding	1
4	COL21A1	Collagen Type XXI Alpha 1 Chain	Protein Coding	1
5	BIRC7	Baculoviral IAP Repeat Containing 7	Protein Coding	1
6	TFEB	Transcription Factor EB	Protein Coding	1
7	VHL	Von Hippel-Lindau Tumor Suppressor	Protein Coding	1
8	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	1
9	TGFB3	Transforming Growth Factor Beta 3	Protein Coding	1
10	TGFB2	Transforming Growth Factor Beta 2	Protein Coding	1
11	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1
12	TGFA	Transforming Growth Factor Alpha	Protein Coding	1
13	TFE3	Transcription Factor Binding To IGHM Enhancer 3	Protein Coding	1
14	ELOC	Elongin C	Protein Coding	1
15	SLC2A1	Solute Carrier Family 2 Member 1	Protein Coding	1
16	SFPQ	Splicing Factor Proline And Glutamine Rich	Protein Coding	1
17	PRCC	Proline Rich Mitotic Checkpoint Control Factor	Protein Coding	1
18	EGLN1	Egl-9 Family Hypoxia Inducible Factor 1	Protein Coding	1
19	PDGFB	Platelet Derived Growth Factor Subunit B	Protein Coding	1
20	ARNT	Aryl Hydrocarbon Receptor Nuclear Translocator	Protein Coding	1
21	HIF1A	Hypoxia Inducible Factor 1 Subunit Alpha	Protein Coding	1
22	SETD2	SET Domain Containing 2, Histone Lysine Methyltransferase	Protein Coding	1
23	FH	Fumarate Hydratase	Protein Coding	1
24	EPAS1	Endothelial PAS Domain Protein 1	Protein Coding	1
25	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
26	DIAPH1	Diaphanous Related Formin 1	Protein Coding	1
27	CTSK	Cathepsin K	Protein Coding	1
28	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
29	EGLN3	Egl-9 Family Hypoxia Inducible Factor 3	Protein Coding	1
30	EGLN2	Egl-9 Family Hypoxia Inducible Factor 2	Protein Coding	1
31	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	1
32	DVL2	Dishevelled Segment Polarity Protein 2	Protein Coding	1
33	ELOB	Elongin B	Protein Coding	1
34	CADM2	Cell Adhesion Molecule 2	Protein Coding	1

Disorders associated with Type 2 papillary renal cell carcinoma SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Renal cell carcinoma with mit translocations	Enrichment	PRCC, SFPQ, TFE3, TFEB	8.93
2	Erythrocytosis, familial, 3	Enrichment	EGLN1, EPAS1	5.21
3	Loeys-dietz syndrome 4	Enrichment	TGFB2, TGFB3	5.21
4	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	4.04
5	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	4.04
6	Autosomal dominant secondary polycythemia	Enrichment	EGLN1, EPAS1	4.04
7	Sporadic pheochromocytoma/secreting paraganglioma	Enrichment	EPAS1, VHL	4.04
8	Renal cell carcinoma, papillary, 1	Enrichment	PRCC, VHL	3.90
9	Multiple enchondromatosis, maffucci type	Enrichment	HIF1A, VHL	3.90
10	Loeys-dietz syndrome	Enrichment	TGFB2, TGFB3	3.66
11	Renal cell carcinoma, nonpapillary	Enrichment	SETD2, VHL	3.20
12	Corpus callosum, agenesis of	Enrichment	CREBBP, SETD2	3.20
13	Isolated corpus callosum agenesis	Enrichment	CREBBP, SETD2	3.20
14	Rare genetic intellectual disability	Enrichment	CREBBP, EP300	3.20
15	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP, SETD2	3.20
16	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	FH, VHL	2.91
17	Scoliosis	Enrichment	CREBBP, CTSK	2.79
18	Hereditary leiomyomatosis and renal cell cancer	Enrichment	FH	2.60
19	Pycnodysostosis	Enrichment	CTSK	2.60
20	Fumarase deficiency	Enrichment	FH	2.60
21	Stomatin-deficient cryohydrocytosis with neurologic defects	Enrichment	SLC2A1	2.60
22	Basal ganglia calcification, idiopathic, 5	Enrichment	PDGFB	2.60
23	Deafness, autosomal dominant 1, with or without thrombocytopenia	Enrichment	DIAPH1	2.60
24	Intellectual developmental disorder, autosomal dominant 70	Enrichment	SETD2	2.60
25	Renal cell carcinoma, xp11-associated	Enrichment	TFE3	2.60
26	Intellectual developmental disorder, x-linked, syndromic, with pigmentary mosaicism and coarse facies	Enrichment	TFE3	2.60
27	Hemoglobin, high altitude adaptation	Enrichment	EGLN1	2.60
28	Microvascular complications of diabetes 1	Enrichment	VEGFA	2.60
29	Leiomyoma cutis	Enrichment	FH	2.60
30	Camurati-engelmann disease 2	Enrichment	TGFB2	2.60
31	Erythrocytosis, familial, 4	Enrichment	EPAS1	2.60
32	Epilepsy, idiopathic generalized 12	Enrichment	SLC2A1	2.60
33	Webb-dattani syndrome	Enrichment	ARNT2	2.60
34	Loeys-dietz syndrome 5	Enrichment	TGFB3	2.60
35	Fumarate hydratase deficiency	Enrichment	FH	2.60
36	Seizures, cortical blindness, and microcephaly syndrome	Enrichment	DIAPH1	2.60
37	Diaph1-related sensorineural hearing loss-thrombocytopenia syndrome	Enrichment	DIAPH1	2.60
38	Menke-hennekam syndrome 1	Enrichment	CREBBP	2.60
39	Luscan-lumish syndrome	Enrichment	SETD2	2.60
40	Rabin-pappas syndrome	Enrichment	SETD2	2.60
41	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	2.60
42	Multiple paragangliomas associated with polycythemia	Enrichment	EPAS1	2.60
43	Epilepsy with myoclonic absences	Enrichment	SLC2A1	2.60
44	Menke-hennekam syndrome	Enrichment	CREBBP	2.60
45	Hereditary cryohydrocytosis with reduced stomatin	Enrichment	SLC2A1	2.60
46	Retinal hemangioblastoma	Enrichment	VHL	2.60
47	Microcephaly	Enrichment	DIAPH1, EP300, SLC2A1	2.45
48	Epilepsy	Enrichment	DIAPH1, SLC2A1	2.35
49	Leiomyoma, uterine	Enrichment	FH	2.30
50	Camurati-engelmann disease 1	Enrichment	TGFB1	2.30
51	Thumb deformity	Enrichment	CREBBP	2.30
52	Dystonia 9	Enrichment	SLC2A1	2.30
53	Dermatofibrosarcoma protuberans	Enrichment	PDGFB	2.30
54	Alveolar soft part sarcoma	Enrichment	TFE3	2.30
55	Glut1 deficiency syndrome 1	Enrichment	SLC2A1	2.30
56	Menke-hennekam syndrome 2	Enrichment	EP300	2.30
57	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	2.30
58	Glucose transporter type 1 deficiency syndrome	Enrichment	SLC2A1	2.30
59	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	2.30
60	Camurati-engelmann disease	Enrichment	TGFB1	2.30
61	Spinocerebellar ataxia 45	Enrichment	FH	2.30
62	Acute leukemia of ambiguous lineage	Enrichment	VHL	2.30
63	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	TGFB2, TGFB3	2.27
64	Myasthenic syndrome, congenital, 6, presynaptic	Enrichment	VHL	2.12
65	Glut1 deficiency syndrome 2	Enrichment	SLC2A1	2.12
66	Primary polycythemia	Enrichment	VHL	2.12
67	Tethered spinal cord syndrome	Enrichment	CREBBP	2.12
68	Nail disorder, nonsyndromic congenital, 9	Enrichment	CTSK	2.12
69	Chromosome 17q23.1-q23.2 deletion syndrome	Enrichment	SLC2A1	2.12
70	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	2.12
71	Renal cell carcinoma	Enrichment	TFE3	2.12
72	Enchondromatosis	Enrichment	HIF1A	2.12
73	Acyl-coa dehydrogenase, very long-chain, deficiency of	Enrichment	DVL2	2.00
74	Erythrocytosis, familial, 2	Enrichment	VHL	2.00
75	Au-kline syndrome	Enrichment	VHL	2.00
76	Malignant epithelioid hemangioendothelioma	Enrichment	TFE3	2.00
77	Enchondromatosis, multiple, ollier type	Enrichment	HIF1A	1.90
78	Arrhythmogenic right ventricular dysplasia, familial, 1	Enrichment	TGFB3	1.90
79	Fanconi anemia, complementation group d2	Enrichment	VHL	1.90
80	Von hippel-lindau syndrome	Enrichment	VHL	1.90
81	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.90
82	Arrhythmogenic right ventricular dysplasia 1	Enrichment	TGFB3	1.90
83	Atrial septal defect 1	Enrichment	TGFB2	1.83
84	Moyamoya disease 1	Enrichment	DIAPH1	1.83
85	Pendred syndrome	Enrichment	DIAPH1	1.83
86	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	1.83
87	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	1.83
88	Hypertrichosis	Enrichment	CREBBP	1.83
89	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A	1.76
90	Paroxysmal dystonia	Enrichment	SLC2A1	1.76
91	Basal ganglia calcification, idiopathic, 1	Enrichment	PDGFB	1.70
92	Alternating hemiplegia of childhood	Enrichment	SLC2A1	1.70
93	Charge syndrome	Enrichment	EP300	1.65
94	Myoclonic-atonic epilepsy	Enrichment	SLC2A1	1.65
95	Marfan syndrome	Enrichment	TGFB2	1.61
96	Primary bone dysplasia	Enrichment	CTSK	1.61
97	Meningioma, familial	Enrichment	PDGFB	1.56
98	Osteochondrodysplasia	Enrichment	CTSK	1.56
99	Septooptic dysplasia	Enrichment	ARNT2	1.53
100	Meningioma	Enrichment	PDGFB	1.53
101	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	TGFB3	1.53
102	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	TGFB3	1.53
103	Pheochromocytoma	Enrichment	VHL	1.46
104	Heart disease	Enrichment	CREBBP	1.46
105	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	TGFB3	1.46
106	Polydactyly, postaxial, type a1	Enrichment	EP300	1.43
107	Hydrocephalus, congenital, 1	Enrichment	SETD2	1.40
108	Dandy-walker syndrome	Enrichment	SETD2	1.38
109	Inherited cancer-predisposing syndrome	Enrichment	FH, VHL	1.37
110	Diffuse large b-cell lymphoma	Enrichment	CREBBP	1.33
111	Ehlers-danlos syndrome	Enrichment	TGFB2	1.33
112	Hepatocellular carcinoma	Enrichment	FH	1.27
113	Tooth agenesis	Enrichment	TGFA	1.27
114	Developmental and epileptic encephalopathy 1	Enrichment	SLC2A1	1.22
115	Auditory neuropathy	Enrichment	DIAPH1	1.20
116	Strabismus	Enrichment	SLC2A1	1.18
117	Bladder cancer	Enrichment	CDKN1A	1.15
118	Cystic fibrosis	Enrichment	TGFB1	1.11
119	Fanconi anemia, complementation group a	Enrichment	VHL	1.07
120	Benign epilepsy with centrotemporal spikes	Enrichment	SLC2A1	1.01
121	Centralopathic epilepsy	Enrichment	SLC2A1	0.99
122	West syndrome	Enrichment	SLC2A1	0.98
123	Myeloma, multiple	Enrichment	CREBBP	0.88
124	Autism	Enrichment	CREBBP	0.78
125	Rare genetic deafness	Enrichment	DIAPH1	0.74
126	Colorectal cancer	Enrichment	EP300	0.71
127	Ovarian cancer	Enrichment	FH	0.65
128	Congenital nervous system abnormality	Enrichment	CREBBP	0.63
129	Nervous system disease	Enrichment	CREBBP	0.63
130	Autism spectrum disorder	Enrichment	SETD2	0.62

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Type 2 papillary renal cell carcinoma

Pathway Network for Type 2 papillary renal cell carcinoma

Member Pathways for Type 2 papillary renal cell carcinoma

Pathways in the Type 2 papillary renal cell carcinoma SuperPath

Associated Genes for Type 2 papillary renal cell carcinoma

Associated Disorders for Type 2 papillary renal cell carcinoma

Disorders associated with Type 2 papillary renal cell carcinoma SuperPath

STRING Interaction Network for Type 2 papillary renal cell carcinoma

Sources for Type 2 papillary renal cell carcinoma