Type I hemidesmosome assembly

No Pathway Network information available for Type I hemidesmosome assembly

Pathways in the Type I hemidesmosome assembly SuperPath

#	Name	Source	Genes
1	Type I hemidesmosome assembly	Reactome	CD151 COL17A1 DST ITGA6 ITGB4 KRT14 KRT5 LAMA3 LAMB3 LAMC2 (see all 10) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	COL17A1	Collagen Type XVII Alpha 1 Chain	Protein Coding	1
2	ITGA6	Integrin Subunit Alpha 6	Protein Coding	1
3	ITGB4	Integrin Subunit Beta 4	Protein Coding	1
4	KRT5	Keratin 5	Protein Coding	1
5	KRT14	Keratin 14	Protein Coding	1
6	LAMA3	Laminin Subunit Alpha 3	Protein Coding	1
7	LAMB3	Laminin Subunit Beta 3	Protein Coding	1
8	LAMC2	Laminin Subunit Gamma 2	Protein Coding	1
9	DST	Dystonin	Protein Coding	1
10	CD151	CD151 Molecule (Raph Blood Group)	Protein Coding	1

Disorders associated with Type I hemidesmosome assembly SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Junctional epidermolysis bullosa	Enrichment	COL17A1, ITGA6, ITGB4, LAMA3, LAMB3, LAMC2	16.00
2	Epidermolysis bullosa, junctional 1a, intermediate	Enrichment	COL17A1, ITGB4, LAMA3, LAMB3, LAMC2	11.87
3	Junctional epidermolysis bullosa non-herlitz type	Enrichment	COL17A1, ITGB4, LAMA3, LAMB3, LAMC2	11.87
4	Skin disease	Enrichment	COL17A1, ITGB4, KRT14, LAMB3, LAMC2	11.23
5	Epidermolysis bullosa simplex 1c, localized	Enrichment	ITGB4, KRT14, KRT5	8.54
6	Epidermolysis bullosa	Enrichment	ITGA6, KRT5, LAMB3	8.54
7	Epidermolysis bullosa, junctional 1b, severe	Enrichment	LAMA3, LAMB3, LAMC2	8.24
8	Epidermolysis bullosa simplex	Enrichment	ITGB4, KRT14, KRT5	8.00
9	Amelogenesis imperfecta, type ia	Enrichment	COL17A1, LAMB3	6.31
10	Epidermolysis bullosa simplex 1d, generalized, intermediate or severe, autosomal recessive	Enrichment	KRT14, KRT5	6.31
11	Localized junctional epidermolysis bullosa, non-herlitz type	Enrichment	COL17A1, ITGB4	6.31
12	Epidermolysis bullosa simplex 1b, generalized intermediate	Enrichment	KRT14, KRT5	5.53
13	Epidermolysis bullosa simplex generalized type	Enrichment	KRT14, KRT5	5.53
14	Epidermolysis bullosa simplex 2f, with mottled pigmentation	Enrichment	KRT14, KRT5	5.31
15	Epidermolysis bullosa simplex 1a, generalized severe	Enrichment	KRT14, KRT5	5.31
16	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	ITGA6, ITGB4	5.14
17	Amelogenesis imperfecta, type ie	Enrichment	COL17A1, LAMB3	4.66
18	Amelogenesis imperfecta	Enrichment	COL17A1, LAMB3	4.42
19	Multiple sclerosis	Enrichment	DST, ITGB4	4.35
20	Dermatopathia pigmentosa reticularis	Enrichment	KRT14	3.13
21	Raph blood group system	Enrichment	CD151	3.13
22	Naegeli-franceschetti-jadassohn syndrome	Enrichment	KRT14	3.13
23	Epidermolysis bullosa simplex 7, with nephropathy and deafness	Enrichment	CD151	3.13
24	Late-onset junctional epidermolysis bullosa	Enrichment	COL17A1	3.13
25	Amelogenesis imperfecta, type ib	Enrichment	COL17A1	2.83
26	Epidermolysis bullosa, junctional 2c, laryngoonychocutaneous	Enrichment	LAMA3	2.83
27	Epidermolysis bullosa simplex 2e, with migratory circinate erythema	Enrichment	KRT5	2.83
28	Epithelial recurrent erosion dystrophy	Enrichment	COL17A1	2.83
29	Epidermolysis bullosa, junctional 3b, severe	Enrichment	LAMC2	2.83
30	Epidermolysis bullosa, junctional 3a, intermediate	Enrichment	LAMC2	2.83
31	Epidermolysis bullosa, junctional 4, intermediate	Enrichment	COL17A1	2.83
32	Epidermolysis bullosa simplex 2d, generalized, intermediate or severe, autosomal recessive	Enrichment	KRT5	2.83
33	Epidermolysis bullosa, junctional 2a, intermediate	Enrichment	LAMA3	2.83
34	Epidermolysis bullosa, junctional 5a, intermediate	Enrichment	ITGB4	2.83
35	Sjogren-larsson syndrome	Enrichment	KRT14	2.83
36	Epidermolysis bullosa, junctional 2b, severe	Enrichment	LAMA3	2.83
37	Epidermolysis bullosa simplex 2a, generalized severe	Enrichment	KRT5	2.83
38	Epidermolysis bullosa simplex 3, localized or generalized intermediate, with bp230 deficiency	Enrichment	DST	2.66
39	Epidermolysis bullosa, junctional 6, with pyloric atresia	Enrichment	ITGA6	2.66
40	Epidermolysis bullosa simplex 2b, generalized intermediate	Enrichment	KRT5	2.66
41	Epidermolysis bullosa simplex 2c, localized	Enrichment	KRT5	2.66
42	Dowling-degos disease 1	Enrichment	KRT5	2.53
43	Epidermolysis bullosa simplex 5c, with pyloric atresia	Enrichment	ITGB4	2.53
44	Neuropathy, hereditary sensory and autonomic, type vi	Enrichment	DST	2.53
45	Dowling-degos disease	Enrichment	KRT5	2.53
46	Corneal dystrophy	Enrichment	COL17A1	2.53
47	Aplasia cutis congenita	Enrichment	ITGB4	2.43
48	Charcot-marie-tooth disease	Enrichment	DST	1.53

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Type I hemidesmosome assembly

Pathway Network for Type I hemidesmosome assembly

Member Pathways for Type I hemidesmosome assembly

Pathways in the Type I hemidesmosome assembly SuperPath

Associated Genes for Type I hemidesmosome assembly

Associated Disorders for Type I hemidesmosome assembly

Disorders associated with Type I hemidesmosome assembly SuperPath

STRING Interaction Network for Type I hemidesmosome assembly

Sources for Type I hemidesmosome assembly