Tyrosine metabolism p.1 (dopamine)

No Pathway Network information available for Tyrosine metabolism p.1 (dopamine)

Pathways in the Tyrosine metabolism p.1 (dopamine) SuperPath

#	Name	Source	Genes
1	Tyrosine metabolism p.1 (dopamine)	GeneGo (Thomson Reuters)	ADH1B ADH7 ALDH1B1 ALDH3A1 ALDH9A1 AOC1 AOC2 AOC3 COMT DBH DDC MAOA MAOB PAH PNMT TH TYR YARS1 (see all 18) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	AOC1	Amine Oxidase Copper Containing 1	Protein Coding	1
2	ADH1B	Alcohol Dehydrogenase 1B (Class I), Beta Polypeptide	Protein Coding	1
3	ADH7	Alcohol Dehydrogenase 7 (Class IV), Mu Or Sigma Polypeptide	Protein Coding	1
4	ALDH3A1	Aldehyde Dehydrogenase 3 Family Member A1	Protein Coding	1
5	ALDH1B1	Aldehyde Dehydrogenase 1 Family Member B1	Protein Coding	1
6	ALDH9A1	Aldehyde Dehydrogenase 9 Family Member A1	Protein Coding	1
7	AOC2	Amine Oxidase Copper Containing 2	Protein Coding	1
8	COMT	Catechol-O-Methyltransferase	Protein Coding	1
9	DBH	Dopamine Beta-Hydroxylase	Protein Coding	1
10	DDC	Dopa Decarboxylase	Protein Coding	1
11	MAOA	Monoamine Oxidase A	Protein Coding	1
12	MAOB	Monoamine Oxidase B	Protein Coding	1
13	PAH	Phenylalanine Hydroxylase	Protein Coding	1
14	PNMT	Phenylethanolamine N-Methyltransferase	Protein Coding	1
15	TH	Tyrosine Hydroxylase	Protein Coding	1
16	TYR	Tyrosinase	Protein Coding	1
17	YARS1	Tyrosyl-TRNA Synthetase 1	Protein Coding	1
18	AOC3	Amine Oxidase Copper Containing 3	Protein Coding	1

Disorders associated with Tyrosine metabolism p.1 (dopamine) SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Rasopathy	Enrichment	DDC, PAH	3.28
2	Albinism, oculocutaneous, type ib	Enrichment	TYR	2.88
3	Charcot-marie-tooth disease, dominant intermediate c	Enrichment	YARS1	2.88
4	Skin/hair/eye pigmentation, variation in, 3	Enrichment	TYR	2.88
5	Brunner syndrome	Enrichment	MAOA	2.88
6	Catechol-o-methyltransferase activity, variation in	Enrichment	COMT	2.88
7	Minimal pigment oculocutaneous albinism type 1	Enrichment	TYR	2.88
8	Tetrahydrobiopterin-responsive hyperphenylalaninemia/phenylketonuria	Enrichment	PAH	2.88
9	Hypopigmentation of the skin	Enrichment	TYR	2.88
10	Segawa syndrome, autosomal recessive	Enrichment	TH	2.58
11	Orthostatic hypotension 1	Enrichment	DBH	2.58
12	Neurodevelopmental disorder with spasticity, hypomyelinating leukodystrophy, and brain abnormalities	Enrichment	PAH	2.58
13	Aromatic l-amino acid decarboxylase deficiency	Enrichment	DDC	2.58
14	Albinism, oculocutaneous, type ia	Enrichment	TYR	2.58
15	Melanoma, cutaneous malignant 8	Enrichment	TYR	2.58
16	Dopamine beta-hydroxylase deficiency	Enrichment	DBH	2.58
17	Dystonia, dopa-responsive	Enrichment	TH	2.40
18	Visceral steatosis, congenital	Enrichment	YARS1	2.40
19	Pituitary hormone deficiency, combined, 2	Enrichment	PAH	2.40
20	Neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset 2	Enrichment	YARS1	2.40
21	Steatotic liver disease	Enrichment	YARS1	2.40
22	Phenylketonuria	Enrichment	PAH	2.28
23	Propionic acidemia	Enrichment	PAH	2.28
24	Neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset 1	Enrichment	YARS1	2.28
25	Alcohol dependence	Enrichment	ADH1B	2.10
26	Hyperphenylalaninemia, bh4-deficient, a	Enrichment	PAH	2.10
27	Albinism, ocular, type i	Enrichment	TYR	2.10
28	Keratoconus	Enrichment	ALDH3A1	2.10
29	Albinism	Enrichment	TYR	2.10
30	Waardenburg syndrome, type 2e	Enrichment	TYR	2.03
31	Oculocutaneous albinism	Enrichment	TYR	2.03
32	Retinal degeneration	Enrichment	YARS1	2.03
33	Optic nerve disease	Enrichment	TYR	1.88
34	Digeorge syndrome	Enrichment	COMT	1.80
35	Pulmonary hypertension, primary, 1	Enrichment	PAH	1.77
36	Myopia	Enrichment	TYR	1.70
37	Skin disease	Enrichment	TYR	1.54
38	Strabismus	Enrichment	TYR	1.45
39	Dystonia	Enrichment	TH	1.34
40	Eye disease	Enrichment	TYR	1.34
41	Bardet-biedl syndrome	Enrichment	COMT	1.27
42	Schizophrenia	Enrichment	COMT	1.12
43	Breast cancer	Enrichment	PAH	1.02

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Tyrosine metabolism p.1 (dopamine)

Pathway Network for Tyrosine metabolism p.1 (dopamine)

Member Pathways for Tyrosine metabolism p.1 (dopamine)

Pathways in the Tyrosine metabolism p.1 (dopamine) SuperPath

Associated Genes for Tyrosine metabolism p.1 (dopamine)

Associated Disorders for Tyrosine metabolism p.1 (dopamine)

Disorders associated with Tyrosine metabolism p.1 (dopamine) SuperPath

STRING Interaction Network for Tyrosine metabolism p.1 (dopamine)

Sources for Tyrosine metabolism p.1 (dopamine)