UMP biosynthesis

Sources:

#	Name	Source	Genes
1	UMP biosynthesis	PubChem	CAD DHODH UMPS
2	Pyrimidine biosynthesis	Reactome	CAD DHODH UMPS
3	UMP biosynthesis I	PubChem	CAD

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CAD	Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, And Dihydroorotase	Protein Coding	3
2	UMPS	Uridine Monophosphate Synthetase	Protein Coding	2
3	DHODH	Dihydroorotate Dehydrogenase (Quinone)	Protein Coding	2

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Developmental and epileptic encephalopathy 50	Enrichment	CAD	3.83
2	Orotic aciduria	Enrichment	UMPS	3.66
3	Miller syndrome	Enrichment	DHODH	3.35
4	Developmental and epileptic encephalopathy 1	Enrichment	CAD	2.73

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for UMP biosynthesis