Validated nuclear estrogen receptor beta network

No Pathway Network information available for Validated nuclear estrogen receptor beta network

Pathways in the Validated nuclear estrogen receptor beta network SuperPath

#	Name	Source	Genes
1	Validated nuclear estrogen receptor beta network	PubChem	C3 DDX54 ESR2 NCOA1 NCOA2 NCOA3 NEDD8 NR0B1 NR0B2 SMARCA4 SMARCB1 SMARCE1 UBA3 UBE2M ZNF14 (see all 15) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ZNF14	Zinc Finger Protein 14	Protein Coding	1
2	DDX54	DEAD-Box Helicase 54	Protein Coding	1
3	NR0B2	Nuclear Receptor Subfamily 0 Group B Member 2	Protein Coding	1
4	NR0B1	Nuclear Receptor Subfamily 0 Group B Member 1	Protein Coding	1
5	SMARCE1	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit E1	Protein Coding	1
6	SMARCB1	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit B1	Protein Coding	1
7	UBA3	Ubiquitin Like Modifier Activating Enzyme 3	Protein Coding	1
8	ESR2	Estrogen Receptor 2	Protein Coding	1
9	C3	Complement C3	Protein Coding	1
10	UBE2M	Ubiquitin Conjugating Enzyme E2 M	Protein Coding	1
11	SMARCA4	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit ATPase 4	Protein Coding	1
12	NCOA3	Nuclear Receptor Coactivator 3	Protein Coding	1
13	NCOA1	Nuclear Receptor Coactivator 1	Protein Coding	1
14	NCOA2	Nuclear Receptor Coactivator 2	Protein Coding	1
15	NEDD8	NEDD8 Ubiquitin Like Modifier	Protein Coding	1

Disorders associated with Validated nuclear estrogen receptor beta network SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Coffin-siris syndrome 1	Enrichment	SMARCA4, SMARCB1, SMARCE1	6.31
2	Rhabdoid tumor predisposition syndrome	Enrichment	SMARCA4, SMARCB1	5.94
3	Meningioma, familial	Enrichment	SMARCB1, SMARCE1	4.20
4	Meningioma	Enrichment	SMARCB1, SMARCE1	4.13
5	Inherited cancer-predisposing syndrome	Enrichment	SMARCA4, SMARCB1, SMARCE1	3.42
6	Hemolytic uremic syndrome, atypical 5	Enrichment	C3	2.96
7	Coffin-siris syndrome 5	Enrichment	SMARCE1	2.96
8	46,xy sex reversal 2	Enrichment	NR0B1	2.96
9	Adrenal hypoplasia, congenital	Enrichment	NR0B1	2.96
10	Ovarian dysgenesis 8	Enrichment	ESR2	2.96
11	Rhabdoid tumor predisposition syndrome 1	Enrichment	SMARCB1	2.96
12	Neurilemmoma	Enrichment	SMARCB1	2.96
13	Macular degeneration, age-related, 9	Enrichment	C3	2.96
14	Complement component 3 deficiency, autosomal recessive	Enrichment	C3	2.96
15	Coffin-siris syndrome 3	Enrichment	SMARCB1	2.96
16	Smarca4-deficient sarcoma of thorax	Enrichment	SMARCA4	2.96
17	Ovarian small cell carcinoma	Enrichment	SMARCA4	2.96
18	Complement component 3 deficiency	Enrichment	C3	2.96
19	Facial cleft	Enrichment	SMARCE1	2.96
20	Membranoproliferative glomerulonephritis	Enrichment	C3	2.96
21	Primary membranoproliferative glomerulonephritis	Enrichment	C3	2.96
22	Rhabdoid tumor predisposition syndrome 2	Enrichment	SMARCA4	2.66
23	Schwannomatosis 1	Enrichment	SMARCB1	2.66
24	Otosclerosis 12	Enrichment	SMARCA4	2.66
25	Coffin-siris syndrome 4	Enrichment	SMARCA4	2.66
26	Thyroid carcinoma, familial medullary	Enrichment	ESR2	2.48
27	Atypical teratoid rhabdoid tumor	Enrichment	SMARCB1	2.48
28	Schwannomatosis	Enrichment	SMARCB1	2.48
29	Genetic atypical hemolytic-uremic syndrome	Enrichment	C3	2.48
30	Full schwannomatosis	Enrichment	SMARCB1	2.35
31	Nonsyndromic 46,xx testicular disorders/differences of sex development	Enrichment	NR0B1	2.26
32	Renal hypoplasia	Enrichment	DDX54	2.18
33	Atypical hemolytic uremic syndrome with complement gene abnormality	Enrichment	C3	2.18
34	Neuroblastoma	Enrichment	SMARCA4	2.05
35	Ventricular septal defect	Enrichment	SMARCA4	2.00
36	Atrial heart septal defect	Enrichment	SMARCA4	1.92
37	46,xy complete gonadal dysgenesis	Enrichment	NR0B1	1.92
38	Interatrial communication	Enrichment	SMARCA4	1.92
39	Hypercholesterolemia, familial, 1	Enrichment	SMARCA4	1.85
40	Nk-cell enteropathy	Enrichment	SMARCB1	1.85
41	46,xy partial gonadal dysgenesis	Enrichment	NR0B1	1.81
42	Atypical hemolytic-uremic syndrome	Enrichment	C3	1.78
43	Familial hypercholesterolemia	Enrichment	SMARCA4	1.78
44	Cleft palate, isolated	Enrichment	SMARCA4	1.73
45	Cerebral palsy	Enrichment	SMARCA4	1.37
46	Body mass index quantitative trait locus 11	Enrichment	NR0B2	1.27
47	Ovarian cancer	Enrichment	SMARCB1	0.97
48	Autism spectrum disorder	Enrichment	SMARCB1	0.94

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Validated nuclear estrogen receptor beta network

Pathway Network for Validated nuclear estrogen receptor beta network

Member Pathways for Validated nuclear estrogen receptor beta network

Pathways in the Validated nuclear estrogen receptor beta network SuperPath

Associated Genes for Validated nuclear estrogen receptor beta network

Associated Disorders for Validated nuclear estrogen receptor beta network

Disorders associated with Validated nuclear estrogen receptor beta network SuperPath

STRING Interaction Network for Validated nuclear estrogen receptor beta network

Sources for Validated nuclear estrogen receptor beta network