Vasopressin-like receptors

Sources:

#	Name	Source	Genes
1	Vasopressin-like receptors	Reactome	AVP AVPR1A AVPR1B AVPR2 OXT OXTR (see all 6) (see less)
2	Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI)	Reactome	AVP AVPR1A AVPR1B
3	Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI)	Reactome	AVP AVPR2

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	AVP	Arginine Vasopressin	Protein Coding	3
2	AVPR1A	Arginine Vasopressin Receptor 1A	Protein Coding	2
3	AVPR1B	Arginine Vasopressin Receptor 1B	Protein Coding	2
4	AVPR2	Arginine Vasopressin Receptor 2	Protein Coding	2
5	OXT	Oxytocin/Neurophysin I Prepropeptide	Protein Coding	1
6	OXTR	Oxytocin Receptor	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Diabetes insipidus, neurohypophyseal	Direct
2	Nephrogenic syndrome of inappropriate antidiuresis	Enrichment	AVPR2	3.35
3	Diabetes insipidus, nephrogenic, 1, x-linked	Enrichment	AVPR2	3.35
4	Central diabetes insipidus	Enrichment	AVP	3.35
5	X-linked nephrogenic diabetes insipidus	Enrichment	AVPR2	3.35
6	Hereditary arginine vasopressin deficiency	Enrichment	AVP	3.35
7	Qualitative or quantitative defects of caveolin-3	Enrichment	OXTR	3.05
8	Rippling muscle disease 2	Enrichment	OXTR	2.88
9	Long qt syndrome 9	Enrichment	OXTR	2.88
10	Myopathy, distal, tateyama type	Enrichment	OXTR	2.88
11	Nephrogenic diabetes insipidus	Enrichment	AVPR2	2.88
12	Diabetes insipidus	Enrichment	AVP	2.75
13	Myopathy, tubular aggregate, 1	Enrichment	OXTR	2.45
14	Creatine phosphokinase, elevated serum	Enrichment	OXTR	2.15
15	Isolated elevated serum creatine phosphokinase levels	Enrichment	OXTR	2.15
16	Cardiomyopathy, familial hypertrophic, 1	Enrichment	OXTR	1.98
17	Long qt syndrome	Enrichment	OXTR	1.87
18	Familial hypertrophic cardiomyopathy	Enrichment	OXTR	1.84

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Vasopressin-like receptors