VEGF binds to VEGFR leading to receptor dimerization

No Pathway Network information available for VEGF binds to VEGFR leading to receptor dimerization

#	Name	Source	Genes
1	VEGF binds to VEGFR leading to receptor dimerization	Reactome	FLT1 FLT4 KDR PGF VEGFA VEGFB VEGFC VEGFD (see all 8) (see less)
2	VEGF ligand-receptor interactions	Reactome	FLT1 FLT4 KDR PGF VEGFA VEGFB VEGFC VEGFD (see all 8) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	VEGFD	Vascular Endothelial Growth Factor D	Protein Coding	2
2	FLT1	Fms Related Receptor Tyrosine Kinase 1	Protein Coding	2
3	FLT4	Fms Related Receptor Tyrosine Kinase 4	Protein Coding	2
4	KDR	Kinase Insert Domain Receptor	Protein Coding	2
5	PGF	Placental Growth Factor	Protein Coding	2
6	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	2
7	VEGFB	Vascular Endothelial Growth Factor B	Protein Coding	2
8	VEGFC	Vascular Endothelial Growth Factor C	Protein Coding	2

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Hemangioma, capillary infantile	Enrichment	FLT4, KDR	5.34
2	Tetralogy of fallot	Enrichment	FLT4, KDR	4.01
3	Hereditary lymphedema id	Enrichment	VEGFC	3.23
4	Lymphatic malformation 4	Enrichment	VEGFC	3.23
5	Microvascular complications of diabetes 1	Enrichment	VEGFA	3.23
6	Congenital heart defects, multiple types, 7	Enrichment	FLT4	3.23
7	Tufted angioma of skin	Enrichment	KDR	3.23
8	Congenital primary lymphedema of gordon	Enrichment	VEGFC	3.23
9	Lymphatic malformation 1	Enrichment	FLT4	2.93
10	Intracranial hypertension, idiopathic	Enrichment	FLT4	2.93
11	Angioma, tufted	Enrichment	KDR	2.93
12	Hereditary lymphedema i	Enrichment	FLT4	2.93
13	Pre-eclampsia	Enrichment	FLT1	2.53
14	Hydrops fetalis, nonimmune	Enrichment	FLT4	1.82
15	Non-immune hydrops fetalis	Enrichment	FLT4	1.74
16	Primary ovarian insufficiency	Enrichment	KDR	1.46

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for VEGF binds to VEGFR leading to receptor dimerization