VEGFA-VEGFR2 signaling

No Pathway Network information available for VEGFA-VEGFR2 signaling

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

Disorders associated with VEGFA-VEGFR2 signaling SuperPath

according to GeneCards Suite gene sharing
#DisorderTypeGenesScore
1Diamond-blackfan anemiaEnrichmentRPL26, RPL27, RPL52.12
2Cole-carpenter syndrome 1EnrichmentP4HB1.95
3Phosphoglycerate kinase 1 deficiencyEnrichmentPGK11.95
4Congenital disorder of glycosylation, type iyEnrichmentSSR41.95
5Hypocalciuric hypercalcemia, familial, type iiiEnrichmentAP2S11.95
6Brachyphalangy, polydactyly, and tibial aplasia/hypoplasiaEnrichmentHMGB11.95
7Rajab interstitial lung disease with brain calcifications 1EnrichmentFARSB1.95
8Macular degeneration, age-related, 7EnrichmentHTRA11.95
9Deafness, autosomal dominant 22EnrichmentMYO61.95
10Parkinson disease 11, autosomal dominantEnrichmentGIGYF21.95
11Spinocerebellar ataxia, autosomal recessive 7EnrichmentTPP11.95
12Congenital myopathy 4b, autosomal recessiveEnrichmentTPM31.95
13Parkinson disease 18, autosomal dominantEnrichmentEIF4G11.95
14Amyotrophic lateral sclerosis 18EnrichmentPFN11.95
15Short stature, developmental delay, and congenital heart defectsEnrichmentTKT1.95
16Myopia 25, autosomal dominantEnrichmentP4HA21.95
17Hyperthyroxinemia, familial dysalbuminemicEnrichmentALB1.95
18Elliptocytosis 1EnrichmentEPB411.95
19Developmental and epileptic encephalopathy 53EnrichmentSYNJ11.95
20Cerebral arteriopathy, autosomal recessive, with subcortical infarcts and leukoencephalopathy 2EnrichmentHTRA11.95
21Neurodevelopmental disorder with microcephaly, ataxia, and seizuresEnrichmentSARS11.95
22Neurodevelopmental disorder with impaired language, behavioral abnormalities, and dysmorphic faciesEnrichmentUBAP2L1.95
23Cardiomyopathy, dilated, 2jEnrichmentFLII1.95
24Leukodystrophy, hypomyelinating, 20EnrichmentCNP1.95
25Deafness, autosomal recessive 37EnrichmentMYO61.95
26Oocyte/zygote/embryo maturation arrest 24EnrichmentTUBA1C1.95
27Lowe oculocerebrorenal syndromeEnrichmentOCRL1.95
28Spinal muscular atrophy with congenital bone fractures 1EnrichmentTRIP41.95
29Bcard syndromeEnrichmentPLOD31.95
30Muscular dystrophy, congenital, davignon-chauveau typeEnrichmentTRIP41.95
31Hyperinsulinemic hypoglycemia, familial, 6EnrichmentGLUD11.95
32Gemistocytic astrocytomaEnrichmentIDH21.95
33Protoplasmic astrocytomaEnrichmentIDH21.95
34Cerebral palsy, spastic quadriplegic, 2EnrichmentKANK11.95
35Diamond-blackfan anemia 11EnrichmentRPL261.95
36D-2-hydroxyglutaric aciduria 2EnrichmentIDH21.95
37Choanal atresia and lymphedemaEnrichmentPTPN141.95
38Developmental and epileptic encephalopathy 110EnrichmentCACNA2D11.95
39Muscular dystrophy, congenital, with cataracts and impaired intellectual developmentEnrichmentINPP5K1.95
40Mixed oligodendroglioma-astrocytomaEnrichmentIDH21.95
41Anaplastic oligoastrocytomaEnrichmentIDH21.95
42Chilton-okur-chung neurodevelopmental syndromeEnrichmentCDC42BPB1.95
43Congenital analbuminemiaEnrichmentALB1.95
44Cutis laxa, autosomal recessive, type iicEnrichmentATP6V1E11.95
45Congenital myopathy 21 with early respiratory failureEnrichmentDNAJB41.95
46Leukodystrophy, hypomyelinating, 15EnrichmentEPRS11.95
47Pheochromocytoma/paraganglioma syndrome 6EnrichmentSLC25A111.95
48AnalbuminemiaEnrichmentALB1.95
49Intellectual developmental disorder, autosomal recessive 81EnrichmentASCC31.95
50Fibrillary astrocytomaEnrichmentIDH21.95
51Acute myocardial infarctionEnrichmentIDH21.95
52Brain calcification, rajab typeEnrichmentFARSB1.95
53Progressive sensorineural hearing loss-hypertrophic cardiomyopathy syndromeEnrichmentMYO61.95
54Cardiomyopathy, dilated, 2mEnrichmentNEXN1.95
55Kuhnt-junius degenerationEnrichmentHTRA11.95
56Asymetric thumb-handgrip weakness-distal myopathyEnrichmentDNAJB41.95
57Immunodeficiency 128EnrichmentCOPG11.95
58Autosomal dominant nonsyndromic hearing loss 22EnrichmentMYO61.95
59Liver cirrhosisEnrichmentFARSB1.95
60Htra1 disorderEnrichmentHTRA11.95
61Htra1-related autosomal dominant cerebral small vessel diseaseEnrichmentHTRA11.95
62Lymphedema-posterior choanal atresia syndromeEnrichmentPTPN141.95
63Male infertility due to obstructive azoospermiaEnrichmentPGK11.95
64Congenital generalized hypercontractile muscle stiffness syndromeEnrichmentTPM31.95
65Distal 17p13.3 microdeletion syndromeEnrichmentYWHAE1.95
66Htra1-related cerebral small vessel diseaseEnrichmentHTRA11.95
67Rare autosomal dominant non-syndromic sensorineural deafness type dfnaEnrichmentACTG1, MYO1C, MYO61.68
68Aortic aneurysm, familial thoracic 4EnrichmentMYH111.65
69Spondyloepimetaphyseal dysplasia, strudwick typeEnrichmentFN11.65
70Fanconi-bickel syndromeEnrichmentLDHA1.65
71Spondylometaphyseal dysplasia, corner fracture typeEnrichmentFN11.65
72Ceroid lipofuscinosis, neuronal, 2EnrichmentTPP11.65
73Immunodeficiency 59 and hypoglycemiaEnrichmentHYOU11.65
74Dent disease 2EnrichmentOCRL1.65
75Histiocytoma, angiomatoid fibrousEnrichmentEWSR11.65
76Diamond-blackfan anemia 6EnrichmentRPL51.65
77Deafness, autosomal dominant 20EnrichmentACTG11.65
78Baraitser-winter syndrome 2EnrichmentACTG11.65
79Vitreoretinal degeneration, snowflake typeEnrichmentGIGYF21.65
80Parkinson disease 20, early-onsetEnrichmentSYNJ11.65
81Cardiomyopathy, dilated, 1ccEnrichmentNEXN1.65
82Leber congenital amaurosis 16EnrichmentGIGYF21.65
83Dystonia 16EnrichmentPRKRA1.65
84Ceroid lipofuscinosis, neuronal, 3EnrichmentTPP11.65
85Intellectual developmental disorder, autosomal recessive 67EnrichmentEIF3F1.65
86Megacystis-microcolon-intestinal hypoperistalsis syndrome 2EnrichmentMYH111.65
87Neutropenia, severe congenital, 8, autosomal dominantEnrichmentSRP541.65
88Microcephaly 21, primary, autosomal recessiveEnrichmentGAPDH1.65
89Glycogen storage disease xiiEnrichmentALDOA1.65
90OligodendrogliomaEnrichmentIDH21.65
91Cardiomyopathy, familial hypertrophic, 20EnrichmentNEXN1.65
92Angiocentric gliomaEnrichmentQKI1.65
93Hemoglobin lepore-beta-thalassemia syndromeEnrichmentHBD1.65
94Interstitial lung and liver diseaseEnrichmentFARSB1.65
95Visceral myopathy 2EnrichmentMYH111.65
96Baraitser-winter cerebrofrontofacial syndromeEnrichmentACTG11.65
97Diamond-blackfan anemia 16EnrichmentRPL271.65
98Anaplastic oligodendrogliomaEnrichmentIDH21.65
99Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 2EnrichmentHTRA11.65
100Mitochondrial dna depletion syndrome 15EnrichmentTFAM1.65
101Houge-janssens syndrome 3EnrichmentPPP2CA1.65
102Intellectual developmental disorder, autosomal dominant 58EnrichmentSET1.65
103Prenatal-onset spinal muscular atrophy with congenital bone fracturesEnrichmentTRIP41.65
104Combined deficiency of factor v and factor viiiEnrichmentLMAN11.65
105D-2-hydroxyglutaric aciduriaEnrichmentIDH21.65
106Sickle cell s-lepore diseaseEnrichmentHBD1.65
107Malignant peripheral nerve sheath tumor with perineurial differentiationEnrichmentHTRA11.65
108Desmoplastic small round cell tumorEnrichmentEWSR11.65
109Malignant triton tumorEnrichmentHTRA11.65
110Centronuclear myopathyEnrichmentTPM3, TRIP41.64
111Parkinson disease, late-onsetEnrichmentEIF4G1, GIGYF21.53
112Myopia 2, autosomal dominantEnrichmentCNP1.48
113Thrombocythemia 1EnrichmentCALR1.48
114Factor v and factor viii, combined deficiency of, 1EnrichmentLMAN11.48
115Glomerulopathy with fibronectin deposits 2EnrichmentFN11.48
116Miller-dieker lissencephaly syndromeEnrichmentYWHAE1.48
117Chromosome 17p13.3, centromeric, duplication syndromeEnrichmentYWHAE1.48
118Oocyte/zygote/embryo maturation arrest 2EnrichmentTUBB81.48
119Dent diseaseEnrichmentOCRL1.48
120Autosomal recessive cutis laxa type ii classic typeEnrichmentATP6V1E11.48
121Anaplastic astrocytomaEnrichmentIDH21.48
122Atypical juvenile parkinsonismEnrichmentSYNJ11.48
123Cole-carpenter syndromeEnrichmentP4HB1.48
124Cap myopathyEnrichmentTPM31.48
125Melanoma of soft tissueEnrichmentEWSR11.48
126Tricuspid valve insufficiencyEnrichmentMYH111.48
127Delta beta-thalassemiaEnrichmentHBD1.48
128Ehlers-danlos syndrome, arthrochalasia type, 1EnrichmentALB1.35
129Megacystis-microcolon-intestinal hypoperistalsis syndrome 1EnrichmentMYH111.35
130Temporal arteritisEnrichmentP4HA21.35
131Budd-chiari syndromeEnrichmentCALR1.35
132Imerslund-grasbeck syndrome 2EnrichmentCDC42BPB1.35
133Hereditary elliptocytosisEnrichmentEPB411.35
134Spastic quadriplegic cerebral palsyEnrichmentKANK11.35
135Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)EnrichmentMYH111.35
136Mitral valve insufficiencyEnrichmentMYH111.35
137Intermediate nemaline myopathyEnrichmentTPM31.35
138Enchondromatosis, multiple, ollier typeEnrichmentIDH21.26
139Visceral myopathy 1EnrichmentMYH111.26
140Smith-magenis syndromeEnrichmentFLII1.26
141Chondrosarcoma, extraskeletal myxoidEnrichmentEWSR11.26
142Ciliary dyskinesia, primary, 40EnrichmentSRP541.26
143Cardiac arrestEnrichmentCACNA2D11.26
144HemangiomaEnrichmentRPL51.26
145Female infertility due to oocyte meiotic arrestEnrichmentTUBB81.26
146Congenital short qt syndromeEnrichmentCACNA2D11.26
147Coloboma of choroid and retinaEnrichmentACTG11.26
148Endometrial stromal sarcomaEnrichmentYWHAE1.26
149Non-syndromic genetic deafnessEnrichmentACTG1, MYO61.21
150Hyperaldosteronism, familial, type iEnrichmentHBD1.18
151Angelman syndromeEnrichmentTPP11.18
152Osteogenesis imperfecta, type iEnrichmentP4HB1.18
153Hyperinsulinemic hypoglycemia, familial, 1EnrichmentGLUD11.18
154Shwachman-diamond syndrome 1EnrichmentSRP541.18
155Epidermolysis bullosa, junctional 5b, with pyloric atresiaEnrichmentMYO61.18
156Developmental and epileptic encephalopathy 36EnrichmentDPM11.18
157Inflammatory myofibroblastic tumorEnrichmentTPM31.18
158Intestinal pseudo-obstructionEnrichmentMYH111.18
159Megaloblastic anemiaEnrichmentCDC42BPB1.18
160Kidney clear cell sarcomaEnrichmentYWHAE1.18
161Nonsyndromic genetic hyperinsulinismEnrichmentGLUD11.18
162Meniere diseaseEnrichmentSHROOM21.12
163MyelofibrosisEnrichmentCALR1.12
164Imerslund-grasbeck syndrome 1EnrichmentCDC42BPB1.12
165Brugada syndrome 1EnrichmentCACNA2D11.12
166Multiple enchondromatosis, maffucci typeEnrichmentIDH21.12
167Essential thrombocythemiaEnrichmentCALR1.12
168Childhood-onset nemaline myopathyEnrichmentTPM31.12
169Nonsyndromic hearing lossEnrichmentACTG1, MYO61.09
170Glioma susceptibility 1EnrichmentIDH21.06
171Ewing sarcomaEnrichmentEWSR11.06
172Neurofibromatosis, type iEnrichmentEWSR11.01
173Neurodevelopmental disorder with dysmorphic facies and distal limb anomaliesEnrichmentEIF3F1.01
174Familial thoracic aortic aneurysm and dissectionEnrichmentMYH111.01
175Cat eye syndromeEnrichmentACTG10.97
176Aplastic anemiaEnrichmentRPL50.97
177Nemaline myopathyEnrichmentTPM30.97
178Atrial heart septal defectEnrichmentRPL50.93
179Interatrial communicationEnrichmentRPL50.93
180Early-onset parkinson's diseaseEnrichmentSYNJ10.90
181Cutis laxaEnrichmentATP6V1E10.90
182Undetermined early-onset epileptic encephalopathyEnrichmentCACNA2D1, SYNJ10.88
183Pulmonary hypertension, primary, 1EnrichmentRPL50.86
184Aortic aneurysm, familial thoracic 1EnrichmentMYH110.83
185Heart diseaseEnrichmentNEXN0.83
186Congenital myopathy 4a, autosomal dominantEnrichmentTPM30.81
187MyopiaEnrichmentMYH110.81
188Neuronal ceroid lipofuscinosisEnrichmentTPP10.81
189Cardiomyopathy, dilated, 1eEnrichmentNEXN0.76
190Congenital disorder of glycosylation, type inEnrichmentSSR30.76
191Arteriovenous malformations of the brainEnrichmentSARS10.71
192Congenital myopathyEnrichmentASCC30.71
193LissencephalyEnrichmentACTG10.67
194Hereditary paraganglioma-pheochromocytoma syndromesEnrichmentSLC25A110.67
195Myocardial infarctionEnrichmentCCT70.66
196Rare genetic deafnessEnrichmentACTG1, MYO60.65
197Dilated cardiomyopathyEnrichmentFLII, NEXN0.64
198Diamond-blackfan anemia 1EnrichmentRPL50.64
199Precursor t-cell acute lymphoblastic leukemiaEnrichmentSET0.64
200Ear malformationEnrichmentMYO60.62
201Developmental and epileptic encephalopathy 1EnrichmentSYNJ10.61
202Brugada syndromeEnrichmentCACNA2D10.59
203RasopathyEnrichmentATP6V1E10.59
204Primary autosomal recessive microcephalyEnrichmentSARS10.52
205CakutEnrichmentACTG10.49
206Left ventricular noncompactionEnrichmentNEXN0.48
207Leukemia, acute myeloidEnrichmentIDH20.44
208MyopathyEnrichmentTPM30.44
209Nephrotic syndromeEnrichmentFN10.41
210West syndromeEnrichmentSYNJ10.41
211Familial thoracic aortic aneurysm and aortic dissectionEnrichmentMYH110.41
212Autosomal dominant non-syndromic intellectual disabilityEnrichmentSET0.36
213Familial isolated dilated cardiomyopathyEnrichmentNEXN0.34
214Frontotemporal dementia and/or amyotrophic lateral sclerosis 7EnrichmentPFN10.32
215Autosomal recessive non-syndromic intellectual disabilityEnrichmentSARS10.32
216SchizophreniaEnrichmentKATNAL20.31
217Breast cancerEnrichmentCACNA2D10.24
218Rare autosomal recessive non-syndromic sensorineural deafness type dfnbEnrichmentMYO60.20
219Leber plus diseaseEnrichmentGIGYF20.18
220Congenital nervous system abnormalityEnrichmentTPP10.15
221Nervous system diseaseEnrichmentTPP10.15
222Autism spectrum disorderEnrichmentCDC42BPB0.15
223MicrocephalyEnrichmentACTG10.12
224Complex neurodevelopmental disorderEnrichmentPPP2CA0.12
225Retinitis pigmentosaEnrichmentGIGYF20.04

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