VEGFR2 mediated cell proliferation

No Pathway Network information available for VEGFR2 mediated cell proliferation

Pathways in the VEGFR2 mediated cell proliferation SuperPath

#	Name	Source	Genes
1	VEGFR2 mediated cell proliferation	Reactome	AHCYL1 CALM1 CALM2 CALM3 HRAS ITPR1 ITPR2 ITPR3 KDR KRAS NRAS PDPK1 PLCG1 PRKCA PRKCB PRKCD PRKCZ RASA1 SPHK1 SRC VEGFA (see all 21) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	AHCYL1	Adenosylhomocysteinase Like 1	Protein Coding	1
2	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	1
3	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	1
4	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	1
5	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	1
6	KDR	Kinase Insert Domain Receptor	Protein Coding	1
7	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	1
8	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	1
9	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	1
10	PLCG1	Phospholipase C Gamma 1	Protein Coding	1
11	PRKCA	Protein Kinase C Alpha	Protein Coding	1
12	PRKCB	Protein Kinase C Beta	Protein Coding	1
13	PRKCD	Protein Kinase C Delta	Protein Coding	1
14	PRKCZ	Protein Kinase C Zeta	Protein Coding	1
15	RASA1	RAS P21 Protein Activator 1	Protein Coding	1
16	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
17	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	1
18	CALM1	Calmodulin 1	Protein Coding	1
19	CALM2	Calmodulin 2	Protein Coding	1
20	CALM3	Calmodulin 3	Protein Coding	1
21	SPHK1	Sphingosine Kinase 1	Protein Coding	1

Disorders associated with VEGFR2 mediated cell proliferation SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	7.89
2	Nevus, epidermal	Enrichment	HRAS, KRAS, NRAS	6.95
3	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3, ITPR3	6.95
4	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	6.75
5	Lung non-small cell carcinoma	Enrichment	HRAS, KRAS, NRAS	6.28
6	Noonan syndrome and noonan-related syndrome	Enrichment	HRAS, KRAS, NRAS	5.84
7	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	5.64
8	Noonan syndrome 1	Enrichment	HRAS, KRAS, NRAS	5.26
9	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	5.16
10	Rasopathy	Enrichment	HRAS, KRAS, NRAS	5.09
11	Differentiated thyroid carcinoma	Enrichment	HRAS, KRAS, NRAS	4.94
12	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	KRAS, NRAS	4.86
13	Hemangioma, capillary infantile	Enrichment	KDR, RASA1	4.47
14	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS, NRAS	4.32
15	Capillary malformation-arteriovenous malformation 1	Enrichment	KRAS, RASA1	4.32
16	Leukemia, chronic myeloid	Enrichment	KRAS, NRAS	4.32
17	Noonan syndrome 3	Enrichment	HRAS, KRAS	4.32
18	Follicular thyroid carcinoma	Enrichment	HRAS, NRAS	4.32
19	Melanocytic nevus syndrome, congenital	Enrichment	HRAS, NRAS	4.20
20	Arteriovenous malformation	Enrichment	HRAS, RASA1	4.09
21	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS, RASA1	3.99
22	Juvenile myelomonocytic leukemia	Enrichment	KRAS, NRAS	3.83
23	Bladder cancer	Enrichment	HRAS, KRAS	3.04
24	Long qt syndrome	Enrichment	CALM1, CALM2	2.99
25	Non-immune hydrops fetalis	Enrichment	HRAS, KRAS	2.99
26	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	2.81
27	Cystic angiomatosis of bone, diffuse	Enrichment	RASA1	2.81
28	Oculoectodermal syndrome	Enrichment	KRAS	2.81
29	Melanosis, neurocutaneous	Enrichment	NRAS	2.81
30	Noonan syndrome 6	Enrichment	NRAS	2.81
31	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	2.81
32	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	2.81
33	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	2.81
34	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	2.81
35	Microvascular complications of diabetes 1	Enrichment	VEGFA	2.81
36	Long qt syndrome 16	Enrichment	CALM3	2.81
37	Thrombocytopenia 6	Enrichment	SRC	2.81
38	Tufted angioma of skin	Enrichment	KDR	2.81
39	Long qt syndrome 15	Enrichment	CALM2	2.81
40	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	2.81
41	Congenital pulmonary airway malformation	Enrichment	KRAS	2.81
42	Gorham's disease	Enrichment	RASA1	2.81
43	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.81
44	Neurocutaneous melanocytosis	Enrichment	NRAS	2.81
45	Leukemia, acute myeloid	Enrichment	KRAS, NRAS	2.76
46	Spinocerebellar ataxia 29	Enrichment	ITPR1	2.51
47	Costello syndrome	Enrichment	HRAS	2.51
48	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	2.51
49	Encephalocraniocutaneous lipomatosis	Enrichment	KRAS	2.51
50	Angioma, tufted	Enrichment	KDR	2.51
51	Long qt syndrome 14	Enrichment	CALM1	2.51
52	Wooly hair nevus	Enrichment	HRAS	2.51
53	Gillespie syndrome	Enrichment	ITPR1	2.33
54	Langerhans cell histiocytosis	Enrichment	NRAS	2.33
55	Wieacker-wolff syndrome	Enrichment	RASA1	2.33
56	Spermatocytoma	Enrichment	HRAS	2.33
57	Cardiofaciocutaneous syndrome 1	Enrichment	KRAS	2.21
58	Diffuse gastric and lobular breast cancer syndrome	Enrichment	KRAS	2.21
59	Spinocerebellar ataxia 15	Enrichment	ITPR1	2.21
60	Cardiofaciocutaneous syndrome	Enrichment	KRAS	2.21
61	Lung sarcomatoid carcinoma	Enrichment	KRAS	2.21
62	Pilocytic astrocytoma	Enrichment	KRAS	2.21
63	Epidermolytic nevus	Enrichment	HRAS	2.21
64	Capillary malformations, congenital	Enrichment	RASA1	2.11
65	Colorectal cancer	Enrichment	NRAS, SRC	2.10
66	Klippel-trenaunay-weber syndrome	Enrichment	RASA1	2.03
67	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	RASA1	2.03
68	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	2.03
69	Basal cell carcinoma 1	Enrichment	RASA1	2.03
70	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1	2.03
71	Breast adenocarcinoma	Enrichment	KRAS	2.03
72	Lung squamous cell carcinoma	Enrichment	KRAS	2.03
73	Myelofibrosis	Enrichment	SRC	1.97
74	Gallbladder cancer	Enrichment	KRAS	1.97
75	Hereditary hemorrhagic telangiectasia	Enrichment	RASA1	1.97
76	Pilomyxoid astrocytoma	Enrichment	KRAS	1.97
77	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	1.91
78	Lip and oral cavity carcinoma	Enrichment	HRAS	1.73
79	Congenital long qt syndrome	Enrichment	ITPR3	1.73
80	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ	1.70
81	Protein-deficiency anemia	Enrichment	NRAS	1.70
82	Multiple sclerosis	Enrichment	ITPR1	1.67
83	Osteoporosis	Enrichment	SRC	1.67
84	Lung cancer susceptibility 3	Enrichment	KRAS	1.67
85	Anterior segment dysgenesis	Enrichment	ITPR1	1.64
86	Lynch syndrome	Enrichment	KRAS	1.64
87	Rhabdomyosarcoma	Enrichment	HRAS	1.61
88	Sudden infant death syndrome	Enrichment	CALM2	1.58
89	Arteriovenous malformations of the brain	Enrichment	KRAS	1.54
90	Pancreatic cancer	Enrichment	KRAS	1.42
91	Tetralogy of fallot	Enrichment	KDR	1.40
92	Hydrops fetalis, nonimmune	Enrichment	HRAS	1.40
93	Lung cancer	Enrichment	KRAS	1.31
94	Gastric cancer	Enrichment	KRAS	1.19
95	Hereditary breast carcinoma	Enrichment	KRAS	1.18
96	Thrombocytopenia	Enrichment	SRC	1.14
97	Spastic ataxia	Enrichment	ITPR1	1.10
98	Hereditary breast ovarian cancer syndrome	Enrichment	KRAS	1.09
99	Myeloma, multiple	Enrichment	KRAS	1.08
100	Primary ovarian insufficiency	Enrichment	KDR	1.06
101	Breast cancer	Enrichment	KRAS	0.96
102	Ovarian cancer	Enrichment	KRAS	0.84

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

VEGFR2 mediated cell proliferation

Pathway Network for VEGFR2 mediated cell proliferation

Member Pathways for VEGFR2 mediated cell proliferation

Pathways in the VEGFR2 mediated cell proliferation SuperPath

Associated Genes for VEGFR2 mediated cell proliferation

Associated Disorders for VEGFR2 mediated cell proliferation

Disorders associated with VEGFR2 mediated cell proliferation SuperPath

STRING Interaction Network for VEGFR2 mediated cell proliferation

Sources for VEGFR2 mediated cell proliferation