VEGFR2 mediated vascular permeability

No Pathway Network information available for VEGFR2 mediated vascular permeability

Pathways in the VEGFR2 mediated vascular permeability SuperPath

#	Name	Source	Genes
1	VEGFR2 mediated vascular permeability	Reactome	AKT1 AKT2 AKT3 CALM1 CALM2 CALM3 CAV1 CDH5 CTNNA1 CTNNB1 CTNND1 HSP90AA1 JUP MAPKAP1 MLST8 MTOR NOS3 PAK1 PAK2 PAK3 PDPK1 PRR5 RAC1 RICTOR THEM4 TRIB3 VAV1 VAV2 VAV3 (see all 29) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	1
2	CDH5	Cadherin 5	Protein Coding	1
3	VAV3	Vav Guanine Nucleotide Exchange Factor 3	Protein Coding	1
4	THEM4	Thioesterase Superfamily Member 4	Protein Coding	1
5	CTNNA1	Catenin Alpha 1	Protein Coding	1
6	CTNNB1	Catenin Beta 1	Protein Coding	1
7	CTNND1	Catenin Delta 1	Protein Coding	1
8	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
9	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	1
10	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	1
11	RICTOR	RPTOR Independent Companion Of MTOR Complex 2	Protein Coding	1
12	HSP90AA1	Heat Shock Protein 90 Alpha Family Class A Member 1	Protein Coding	1
13	JUP	Junction Plakoglobin	Protein Coding	1
14	NOS3	Nitric Oxide Synthase 3	Protein Coding	1
15	PAK1	P21 (RAC1) Activated Kinase 1	Protein Coding	1
16	PAK2	P21 (RAC1) Activated Kinase 2	Protein Coding	1
17	PAK3	P21 (RAC1) Activated Kinase 3	Protein Coding	1
18	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	1
19	PRR5	Proline Rich 5	Protein Coding	1
20	TRIB3	Tribbles Pseudokinase 3	Protein Coding	1
21	RAC1	Rac Family Small GTPase 1	Protein Coding	1
22	MLST8	MTOR Associated Protein MLST8	Protein Coding	1
23	VAV1	Vav Guanine Nucleotide Exchange Factor 1	Protein Coding	1
24	VAV2	Vav Guanine Nucleotide Exchange Factor 2	Protein Coding	1
25	MAPKAP1	MAPK Associated Protein 1	Protein Coding	1
26	CALM1	Calmodulin 1	Protein Coding	1
27	CALM2	Calmodulin 2	Protein Coding	1
28	CALM3	Calmodulin 3	Protein Coding	1
29	CAV1	Caveolin 1	Protein Coding	1

Disorders associated with VEGFR2 mediated vascular permeability SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	6.31
2	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3	4.46
3	Hemimegalencephaly	Enrichment	AKT3, MTOR	4.36
4	Colorectal cancer	Enrichment	AKT1, CTNNA1, CTNNB1	3.08
5	Long qt syndrome	Enrichment	CALM1, CALM2	2.70
6	Proteus syndrome	Enrichment	AKT1	2.67
7	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	2.67
8	Intellectual developmental disorder, x-linked 30	Enrichment	PAK3	2.67
9	Arrhythmogenic right ventricular dysplasia, familial, 12	Enrichment	JUP	2.67
10	Lipodystrophy, congenital generalized, type 3	Enrichment	CAV1	2.67
11	Macular dystrophy, patterned, 2	Enrichment	CTNNA1	2.67
12	Pulmonary hypertension, primary, 3	Enrichment	CAV1	2.67
13	Naxos disease	Enrichment	JUP	2.67
14	Knobloch syndrome 2	Enrichment	PAK2	2.67
15	Intellectual developmental disorder with macrocephaly, seizures, and speech delay	Enrichment	PAK1	2.67
16	Lipodystrophy, familial partial, type 7	Enrichment	CAV1	2.67
17	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	2.67
18	Long qt syndrome 16	Enrichment	CALM3	2.67
19	Cowden syndrome 6	Enrichment	AKT1	2.67
20	Adenoid ameloblastoma	Enrichment	CTNNB1	2.67
21	Long qt syndrome 15	Enrichment	CALM2	2.67
22	Capillary hemangioma	Enrichment	AKT3	2.67
23	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	2.67
24	Microcystic stromal tumor	Enrichment	CTNNB1	2.67
25	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	2.67
26	Blepharocheilodontic syndrome 1	Enrichment	CTNND1	2.37
27	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	2.37
28	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	2.37
29	Long qt syndrome 14	Enrichment	CALM1	2.37
30	Blepharocheilodontic syndrome 2	Enrichment	CTNND1	2.37
31	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	2.37
32	Cebalid syndrome	Enrichment	MTOR	2.37
33	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	2.37
34	Senior-loken syndrome 7	Enrichment	AKT3	2.37
35	Bardet-biedl syndrome 16	Enrichment	AKT3	2.37
36	Smith-kingsmore syndrome	Enrichment	MTOR	2.37
37	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	2.37
38	Teratoma	Enrichment	CTNNB1	2.37
39	Desmoid disease, hereditary	Enrichment	CTNNB1	2.19
40	Epidermolysis bullosa, lethal acantholytic	Enrichment	JUP	2.19
41	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	2.19
42	Anus, imperforate	Enrichment	CTNNB1	2.19
43	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	2.19
44	Desmoid tumor	Enrichment	CTNNB1	2.19
45	Butterfly-shaped pigment dystrophy	Enrichment	CTNNA1	2.19
46	Primary ovarian insufficiency	Enrichment	NOS3, RICTOR	2.15
47	Diffuse gastric and lobular breast cancer syndrome	Enrichment	CTNNA1	2.07
48	Polyposis syndrome, hereditary mixed, 1	Enrichment	CTNNA1	2.07
49	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3	2.07
50	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3	2.07
51	Focal cortical dysplasia, type ii	Enrichment	MTOR	2.07
52	Pilomatrixoma	Enrichment	CTNNB1	2.07
53	Alazami syndrome	Enrichment	CTNNB1	2.07
54	Craniopharyngioma	Enrichment	CTNNB1	2.07
55	Knobloch syndrome	Enrichment	PAK2	2.07
56	Isolated focal cortical dysplasia type ii	Enrichment	MTOR	2.07
57	Alzheimer disease 2	Enrichment	NOS3	1.97
58	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	1.97
59	Knobloch syndrome 1	Enrichment	PAK2	1.97
60	Pre-eclampsia	Enrichment	NOS3	1.97
61	Diffuse cutaneous systemic sclerosis	Enrichment	CAV1	1.97
62	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.89
63	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	1.89
64	Adrenocortical carcinoma	Enrichment	CTNNB1	1.89
65	Limited scleroderma	Enrichment	CAV1	1.89
66	Breast adenocarcinoma	Enrichment	AKT1	1.89
67	Cleft lip with or without cleft palate	Enrichment	CTNND1	1.89
68	Renal cell carcinoma, papillary, 1	Enrichment	MTOR	1.83
69	Gallbladder cancer	Enrichment	CTNNB1	1.83
70	Megacolon	Enrichment	AKT3	1.83
71	Overgrowth syndrome	Enrichment	MTOR	1.83
72	Exudative vitreoretinopathy	Enrichment	CTNNB1	1.77
73	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	1.77
74	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1	1.72
75	Adult hepatocellular carcinoma	Enrichment	CTNNB1	1.72
76	Cowden syndrome	Enrichment	AKT1	1.72
77	Ovarian cancer	Enrichment	AKT1, CTNNB1	1.71
78	Stroke, ischemic	Enrichment	NOS3	1.67
79	Polymicrogyria	Enrichment	AKT3	1.67
80	Heritable pulmonary arterial hypertension	Enrichment	CAV1	1.63
81	Meningioma	Enrichment	AKT1	1.60
82	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	JUP	1.60
83	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	JUP	1.60
84	Microcephaly	Enrichment	CTNNB1, PAK3	1.55
85	Medulloblastoma	Enrichment	CTNNB1	1.53
86	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	JUP	1.53
87	Renal cell carcinoma, nonpapillary	Enrichment	MTOR	1.50
88	Rare genetic intellectual disability	Enrichment	MTOR	1.50
89	Wolff-parkinson-white syndrome	Enrichment	JUP	1.47
90	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	JUP	1.47
91	Alzheimer disease, familial, 1	Enrichment	NOS3	1.45
92	Hypertension, essential	Enrichment	NOS3	1.45
93	Sudden infant death syndrome	Enrichment	CALM2	1.45
94	Polycystic liver disease	Enrichment	CTNNB1	1.45
95	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	1.45
96	Craniosynostosis	Enrichment	CTNNA1	1.38
97	Hepatoblastoma	Enrichment	CTNNB1	1.36
98	Hepatocellular carcinoma	Enrichment	CTNNB1	1.34
99	Bladder cancer	Enrichment	CTNNB1	1.22
100	Type 2 diabetes mellitus	Enrichment	AKT2	1.07
101	Hereditary breast carcinoma	Enrichment	AKT1	1.05
102	Hereditary breast ovarian cancer syndrome	Enrichment	CTNNA1	0.95
103	Breast cancer	Enrichment	AKT1	0.83
104	Dilated cardiomyopathy	Enrichment	JUP	0.80
105	Congenital nervous system abnormality	Enrichment	CTNNB1	0.69
106	Nervous system disease	Enrichment	CTNNB1	0.69
107	Complex neurodevelopmental disorder	Enrichment	PAK3	0.63
108	Inherited cancer-predisposing syndrome	Enrichment	CTNNA1	0.61
109	Hereditary retinal dystrophy	Enrichment	CTNNA1	0.33
110	Fundus dystrophy	Enrichment	CTNNA1	0.33

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

VEGFR2 mediated vascular permeability

Pathway Network for VEGFR2 mediated vascular permeability

Member Pathways for VEGFR2 mediated vascular permeability

Pathways in the VEGFR2 mediated vascular permeability SuperPath

Associated Genes for VEGFR2 mediated vascular permeability

Associated Disorders for VEGFR2 mediated vascular permeability

Disorders associated with VEGFR2 mediated vascular permeability SuperPath

STRING Interaction Network for VEGFR2 mediated vascular permeability

Sources for VEGFR2 mediated vascular permeability