Visual signal transduction: Cones

No Pathway Network information available for Visual signal transduction: Cones

Pathways in the Visual signal transduction: Cones SuperPath

#	Name	Source	Genes
1	Visual signal transduction: Cones	PubChem	ARR3 CNGA3 CNGB3 GNAT2 GNB3 GNB5 GNGT2 GRK1 GRK7 GUCY2D GUCY2F LRAT OPN1MW OPN1MW3 PDE6C PDE6H RDH12 RDH5 RGS9 RGS9BP RPE65 SLC24A2 (see all 22) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CNGB3	Cyclic Nucleotide Gated Channel Subunit Beta 3	Protein Coding	1
2	CNGA3	Cyclic Nucleotide Gated Channel Subunit Alpha 3	Protein Coding	1
3	GRK7	G Protein-Coupled Receptor Kinase 7	Protein Coding	1
4	SLC24A2	Solute Carrier Family 24 Member 2	Protein Coding	1
5	RDH5	Retinol Dehydrogenase 5	Protein Coding	1
6	ARR3	Arrestin 3	Protein Coding	1
7	GUCY2F	Guanylate Cyclase 2F, Retinal	Protein Coding	1
8	PDE6H	Phosphodiesterase 6H	Protein Coding	1
9	PDE6C	Phosphodiesterase 6C	Protein Coding	1
10	GUCY2D	Guanylate Cyclase 2D, Retinal	Protein Coding	1
11	RGS9	Regulator Of G Protein Signaling 9	Protein Coding	1
12	GNB3	G Protein Subunit Beta 3	Protein Coding	1
13	GNGT2	G Protein Subunit Gamma Transducin 2	Protein Coding	1
14	GNB5	G Protein Subunit Beta 5	Protein Coding	1
15	GNAT2	G Protein Subunit Alpha Transducin 2	Protein Coding	1
16	RGS9BP	Regulator Of G Protein Signaling 9 Binding Protein	Protein Coding	1
17	GRK1	G Protein-Coupled Receptor Kinase 1	Protein Coding	1
18	OPN1MW	Opsin 1, Medium Wave Sensitive	Protein Coding	1
19	OPN1MW3	Opsin 1, Medium Wave Sensitive 3	Protein Coding	1
20	RDH12	Retinol Dehydrogenase 12	Protein Coding	1
21	RPE65	Retinoid Isomerohydrolase RPE65	Protein Coding	1
22	LRAT	Lecithin Retinol Acyltransferase	Protein Coding	1

Disorders associated with Visual signal transduction: Cones SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Achromatopsia	Enrichment	CNGA3, CNGB3, GNAT2, OPN1MW, PDE6C, PDE6H	11.36
2	Hereditary retinal dystrophy	Enrichment	CNGA3, CNGB3, GNAT2, GRK1, GUCY2D, LRAT, PDE6C, PDE6H, RDH12, RDH5, RGS9, RPE65	10.73
3	Fundus dystrophy	Enrichment	CNGA3, CNGB3, GNAT2, GRK1, GUCY2D, LRAT, PDE6C, PDE6H, RDH12, RDH5, RGS9, RPE65	10.73
4	Eye disease	Enrichment	CNGA3, CNGB3, GNAT2, LRAT, PDE6C, RDH12, RPE65	10.73
5	Cone-rod dystrophy 6	Enrichment	CNGB3, GNAT2, GUCY2D, PDE6C	8.29
6	Leber plus disease	Enrichment	CNGB3, GUCY2D, LRAT, RDH12, RGS9, RPE65	8.16
7	Cone dystrophy	Enrichment	CNGA3, GNAT2, GUCY2D, PDE6C	7.27
8	Cone-rod dystrophy 2	Enrichment	CNGA3, CNGB3, GUCY2D, OPN1MW, RDH12	7.17
9	Stargardt disease 1	Enrichment	CNGB3, LRAT, RDH12, RPE65	6.86
10	Optic atrophy plus syndrome	Enrichment	CNGA3, CNGB3, GUCY2D, RDH5	6.17
11	Retinitis pigmentosa	Enrichment	CNGB3, GUCY2D, LRAT, RDH12, RDH5, RPE65	6.09
12	Achromatopsia 3	Enrichment	CNGA3, CNGB3	5.60
13	Bradyopsia	Enrichment	RGS9, RGS9BP	5.60
14	Congenital stationary night blindness	Enrichment	GNB3, GRK1, RDH5	5.19
15	Leber congenital amaurosis 1	Enrichment	GUCY2D, LRAT	4.16
16	Achromatopsia 2	Enrichment	CNGA3	2.79
17	Colorblindness, partial, deutan series	Enrichment	OPN1MW	2.79
18	Achromatopsia 6	Enrichment	PDE6H	2.79
19	Leber congenital amaurosis 2	Enrichment	RPE65	2.79
20	Retinitis pigmentosa 87 with choroidal involvement	Enrichment	RPE65	2.79
21	Night blindness, congenital stationary, type1i	Enrichment	GUCY2D	2.79
22	Myopia 26, x-linked, female-limited	Enrichment	ARR3	2.79
23	Retinal cone dystrophy 3a	Enrichment	PDE6H	2.79
24	Prolonged electroretinal response suppression 1	Enrichment	RGS9	2.79
25	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	2.79
26	Cone dystrophy 4	Enrichment	PDE6C	2.79
27	Retinitis pigmentosa 20	Enrichment	RPE65	2.79
28	Red-green color blindness	Enrichment	OPN1MW	2.79
29	Blue cone monochromacy	Enrichment	OPN1MW	2.49
30	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	2.49
31	Oguchi disease 2	Enrichment	GRK1	2.49
32	Acth deficiency, isolated	Enrichment	RPE65	2.49
33	Prolonged electroretinal response suppression 2	Enrichment	RGS9BP	2.49
34	Leber congenital amaurosis 14	Enrichment	LRAT	2.49
35	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	2.49
36	Congenital isolated adrenocorticotropic hormone deficiency	Enrichment	RPE65	2.49
37	X-linked cone dysfunction syndrome with myopia	Enrichment	OPN1MW	2.49
38	Oguchi disease	Enrichment	GRK1	2.49
39	Leber congenital amaurosis 13	Enrichment	RDH12	2.31
40	Polr3-related leukodystrophy	Enrichment	GUCY2D	2.31
41	Achromatopsia 4	Enrichment	GNAT2	2.19
42	Macular dystrophy with or without cone dysfunction	Enrichment	RDH12	2.19
43	Color blindness	Enrichment	CNGA3	2.19
44	Choroidal dystrophy, central areolar, 1	Enrichment	GUCY2D	2.09
45	3-methylglutaconic aciduria, type iii	Enrichment	GUCY2D	2.09
46	Macular degeneration	Enrichment	CNGA3	2.09
47	Fundus albipunctatus	Enrichment	RDH5	1.95
48	Retinal degeneration	Enrichment	RPE65	1.95
49	Isolated macular dystrophy	Enrichment	PDE6C	1.65
50	Hypertension, essential	Enrichment	GNB3	1.56
51	Attention deficit-hyperactivity disorder	Enrichment	GNB5	1.45
52	Autism	Enrichment	RPE65	0.96
53	Congenital nervous system abnormality	Enrichment	GNB5	0.80
54	Nervous system disease	Enrichment	GNB5	0.80

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Visual signal transduction: Cones

Pathway Network for Visual signal transduction: Cones

Member Pathways for Visual signal transduction: Cones

Pathways in the Visual signal transduction: Cones SuperPath

Associated Genes for Visual signal transduction: Cones

Associated Disorders for Visual signal transduction: Cones

Disorders associated with Visual signal transduction: Cones SuperPath

STRING Interaction Network for Visual signal transduction: Cones

Sources for Visual signal transduction: Cones