Vitamin D receptor pathway

No Pathway Network information available for Vitamin D receptor pathway

Pathways in the Vitamin D receptor pathway SuperPath

#	Name	Source	Genes
1	Vitamin D receptor pathway	WikiPathways	ABCA11P ABCB1 ABCD1 ADAMTS5 ADGRE5 ADRA1B ADRB2 ALOX5 ALPG ALPI ASAP2 ATP2B1 ATP2C2 BCL6 BDKRB1 BGLAP BMP6 BTLA CA9 CAMP CASP14 CASP5 CBS CCNC CCND1 CCNE1 CD14 CD200 CD40 CD9 CDC34 CDK2 CDKAL1 CDKN1A CDKN1B CDKN2A CDKN2B CDKN2C CDKN2D CDX2 CEACAM1 CEBPA CLDN2 CLEC16A CLMN CLPTM1L COL13A1 COLEC11 CRACR2A CRACR2B CREG2 CST1 CST6 CTLA4 CYP1A1 CYP24A1 CYP27B1 CYP2B6 CYP2C9 CYP2D6 CYP2S1 CYP3A4 CYP3A5 CYP7A1 DACT2 DEFB109C DEFB132 DEFB4A DND1 DNER DUSP10 EFNA5 EPHB4 FGF23 FOXO1 G0S2 G6PD GADD45A GXYLT2 HIF1A HILPDA HLA-DQA1 HLA-DRB1 HNF1A HSD17B2 ID1 ID4 IGFBP1 IGFBP3 IGFBP5 IGSF9B IL12A IL1RL1 IL25 IRF4 IRF5 IRF8 ITGAM JUNB KL KLF4 KLK6 KNG1 KRT13 KRT16 KRT34 KRT38 KRT71 KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-9 KRTAP12-2 KRTAP4-1 KRTAP5-1 KRTAP5-4 KRTAP8-1 LCE1D LCE1F LCE2B LGALS9 LPGAT1 LRP5 LRRC25 LRRC8A MED9 MEG8 MX2 MXD1 MYC MYO9B NFATC2 NINJ1 NOX1 NRIP1 ORM1 ORM2 PNOC PPARD PRDM1 PRKCQ PTGER4 PTH PTHLH RASGRP1 RXRA S100A2 S100A4 S100A6 S100A8 S100A9 S100G SALL4 SATB1 SEMA3B SERPINB1 SFRP1 SLC2A4 SLC34A2 SLC37A2 SLC8A1 SOSTDC1 SPP1 SPRR1B STAM STEAP4 STS SULT1C2 SULT2A1 TGFB1 TGFB2 THBD TIMP2 TIMP3 TNFAIP3 TNFRSF11B TNFSF11 TNFSF4 TPM1 TRAK1 TREM1 TRPV5 TRPV6 VDR ZNF257 (see all 185) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	GXYLT2	Glucoside Xylosyltransferase 2	Protein Coding	1
2	ALPI	Alkaline Phosphatase, Intestinal	Protein Coding	1
3	LPGAT1	Lysophosphatidylglycerol Acyltransferase 1	Protein Coding	1
4	ADGRE5	Adhesion G Protein-Coupled Receptor E5	Protein Coding	1
5	CD40	CD40 Molecule	Protein Coding	1
6	KL	Klotho	Protein Coding	1
7	KLF4	KLF Transcription Factor 4	Protein Coding	1
8	CD14	CD14 Molecule	Protein Coding	1
9	CD9	CD9 Molecule	Protein Coding	1
10	IL1RL1	Interleukin 1 Receptor Like 1	Protein Coding	1
11	CLDN2	Claudin 2	Protein Coding	1
12	CCNE1	Cyclin E1	Protein Coding	1
13	CBS	Cystathionine Beta-Synthase	Protein Coding	1
14	TNFSF11	TNF Superfamily Member 11	Protein Coding	1
15	NRIP1	Nuclear Receptor Interacting Protein 1	Protein Coding	1
16	CAMP	Cathelicidin Antimicrobial Peptide	Protein Coding	1
17	CLPTM1L	CLPTM1 Like	Protein Coding	1
18	FGF23	Fibroblast Growth Factor 23	Protein Coding	1
19	STEAP4	STEAP4 Metalloreductase	Protein Coding	1
20	COLEC11	Collectin Subfamily Member 11	Protein Coding	1
21	SEMA3B	Semaphorin 3B	Protein Coding	1
22	CA9	Carbonic Anhydrase 9	Protein Coding	1
23	VDR	Vitamin D Receptor	Protein Coding	1
24	TNFSF4	TNF Superfamily Member 4	Protein Coding	1
25	TPM1	Tropomyosin 1	Protein Coding	1
26	TNFAIP3	TNF Alpha Induced Protein 3	Protein Coding	1
27	TIMP3	TIMP Metallopeptidase Inhibitor 3	Protein Coding	1
28	TIMP2	TIMP Metallopeptidase Inhibitor 2	Protein Coding	1
29	THBD	Thrombomodulin	Protein Coding	1
30	TGFB2	Transforming Growth Factor Beta 2	Protein Coding	1
31	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1
32	HNF1A	HNF1 Homeobox A	Protein Coding	1
33	SULT2A1	Sulfotransferase Family 2A Member 1	Protein Coding	1
34	SULT1C2	Sulfotransferase Family 1C Member 2	Protein Coding	1
35	SPP1	Secreted Phosphoprotein 1	Protein Coding	1
36	SLC8A1	Solute Carrier Family 8 Member A1	Protein Coding	1
37	BMP6	Bone Morphogenetic Protein 6	Protein Coding	1
38	SLC2A4	Solute Carrier Family 2 Member 4	Protein Coding	1
39	SFRP1	Secreted Frizzled Related Protein 1	Protein Coding	1
40	PRDM1	PR/SET Domain 1	Protein Coding	1
41	CEACAM1	CEA Cell Adhesion Molecule 1	Protein Coding	1
42	BGLAP	Bone Gamma-Carboxyglutamate Protein	Protein Coding	1
43	SATB1	SATB Homeobox 1	Protein Coding	1
44	S100A9	S100 Calcium Binding Protein A9	Protein Coding	1
45	S100A8	S100 Calcium Binding Protein A8	Protein Coding	1
46	S100A6	S100 Calcium Binding Protein A6	Protein Coding	1
47	S100A4	S100 Calcium Binding Protein A4	Protein Coding	1
48	RXRA	Retinoid X Receptor Alpha	Protein Coding	1
49	BDKRB1	Bradykinin Receptor B1	Protein Coding	1
50	BCL6	BCL6 Transcription Repressor	Protein Coding	1
51	CCND1	Cyclin D1	Protein Coding	1
52	PTHLH	Parathyroid Hormone Like Hormone	Protein Coding	1
53	PTH	Parathyroid Hormone	Protein Coding	1
54	PTGER4	Prostaglandin E Receptor 4	Protein Coding	1
55	SALL4	Spalt Like Transcription Factor 4	Protein Coding	1
56	LRRC8A	Leucine Rich Repeat Containing 8 VRAC Subunit A	Protein Coding	1
57	PRKCQ	Protein Kinase C Theta	Protein Coding	1
58	TRPV6	Transient Receptor Potential Cation Channel Subfamily V Member 6	Protein Coding	1
59	CDKAL1	CDKAL1 Threonylcarbamoyladenosine TRNA Methylthiotransferase	Protein Coding	1
60	PPARD	Peroxisome Proliferator Activated Receptor Delta	Protein Coding	1
61	TREM1	Triggering Receptor Expressed On Myeloid Cells 1	Protein Coding	1
62	PNOC	Prepronociceptin	Protein Coding	1
63	ABCB1	ATP Binding Cassette Subfamily B Member 1	Protein Coding	1
64	G0S2	G0/G1 Switch 2	Protein Coding	1
65	ORM2	Orosomucoid 2	Protein Coding	1
66	ORM1	Orosomucoid 1	Protein Coding	1
67	TNFRSF11B	TNF Receptor Superfamily Member 11b	Protein Coding	1
68	ATP2B1	ATPase Plasma Membrane Ca2+ Transporting 1	Protein Coding	1
69	NINJ1	Ninjurin 1	Protein Coding	1
70	NFATC2	Nuclear Factor Of Activated T Cells 2	Protein Coding	1
71	MYO9B	Myosin IXB	Protein Coding	1
72	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	1
73	MX2	MX Dynamin Like GTPase 2	Protein Coding	1
74	STS	Steroid Sulfatase	Protein Coding	1
75	MXD1	MAX Dimerization Protein 1	Protein Coding	1
76	LRP5	LDL Receptor Related Protein 5	Protein Coding	1
77	LGALS9	Galectin 9	Protein Coding	1
78	KRT16	Keratin 16	Protein Coding	1
79	KRT13	Keratin 13	Protein Coding	1
80	KNG1	Kininogen 1	Protein Coding	1
81	JUNB	JunB Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
82	ITGAM	Integrin Subunit Alpha M	Protein Coding	1
83	IRF5	Interferon Regulatory Factor 5	Protein Coding	1
84	IRF4	Interferon Regulatory Factor 4	Protein Coding	1
85	IL12A	Interleukin 12A	Protein Coding	1
86	IGFBP5	Insulin Like Growth Factor Binding Protein 5	Protein Coding	1
87	IGFBP3	Insulin Like Growth Factor Binding Protein 3	Protein Coding	1
88	IGFBP1	Insulin Like Growth Factor Binding Protein 1	Protein Coding	1
89	ID4	Inhibitor Of DNA Binding 4	Protein Coding	1
90	ID1	Inhibitor Of DNA Binding 1	Protein Coding	1
91	IRF8	Interferon Regulatory Factor 8	Protein Coding	1
92	HSD17B2	Hydroxysteroid 17-Beta Dehydrogenase 2	Protein Coding	1
93	HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	Protein Coding	1
94	HLA-DQA1	Major Histocompatibility Complex, Class II, DQ Alpha 1	Protein Coding	1
95	HIF1A	Hypoxia Inducible Factor 1 Subunit Alpha	Protein Coding	1
96	HILPDA	Hypoxia Inducible Lipid Droplet Associated	Protein Coding	1
97	CYP2S1	Cytochrome P450 Family 2 Subfamily S Member 1	Protein Coding	1
98	NOX1	NADPH Oxidase 1	Protein Coding	1
99	LCE2B	Late Cornified Envelope 2B	Protein Coding	1
100	G6PD	Glucose-6-Phosphate Dehydrogenase	Protein Coding	1
101	ALPG	Alkaline Phosphatase, Germ Cell	Protein Coding	1
102	ALOX5	Arachidonate 5-Lipoxygenase	Protein Coding	1
103	CASP14	Caspase 14	Protein Coding	1
104	CLEC16A	C-Type Lectin Domain Containing 16A	Protein Coding	1
105	FOXO1	Forkhead Box O1	Protein Coding	1
106	TRAK1	Trafficking Kinesin Protein 1	Protein Coding	1
107	ABCD1	ATP Binding Cassette Subfamily D Member 1	Protein Coding	1
108	EPHB4	EPH Receptor B4	Protein Coding	1
109	EFNA5	Ephrin A5	Protein Coding	1
110	DACT2	Dishevelled Binding Antagonist Of Beta Catenin 2	Protein Coding	1
111	DEFB4A	Defensin Beta 4A	Protein Coding	1
112	GADD45A	Growth Arrest And DNA Damage Inducible Alpha	Protein Coding	1
113	CYP27B1	Cytochrome P450 Family 27 Subfamily B Member 1	Protein Coding	1
114	CYP24A1	Cytochrome P450 Family 24 Subfamily A Member 1	Protein Coding	1
115	CYP7A1	Cytochrome P450 Family 7 Subfamily A Member 1	Protein Coding	1
116	CYP3A5	Cytochrome P450 Family 3 Subfamily A Member 5	Protein Coding	1
117	CYP3A4	Cytochrome P450 Family 3 Subfamily A Member 4	Protein Coding	1
118	CYP2D6	Cytochrome P450 Family 2 Subfamily D Member 6 (Gene/Pseudogene)	Protein Coding	1
119	CYP2C9	Cytochrome P450 Family 2 Subfamily C Member 9	Protein Coding	1
120	CYP2B6	Cytochrome P450 Family 2 Subfamily B Member 6	Protein Coding	1
121	CYP1A1	Cytochrome P450 Family 1 Subfamily A Member 1	Protein Coding	1
122	ADRB2	Adrenoceptor Beta 2	Protein Coding	1
123	CTLA4	Cytotoxic T-Lymphocyte Associated Protein 4	Protein Coding	1
124	CST6	Cystatin E/M	Protein Coding	1
125	ADRA1B	Adrenoceptor Alpha 1B	Protein Coding	1
126	CST1	Cystatin SN	Protein Coding	1
127	COL13A1	Collagen Type XIII Alpha 1 Chain	Protein Coding	1
128	ZNF257	Zinc Finger Protein 257	Protein Coding	1
129	KRT71	Keratin 71	Protein Coding	1
130	DUSP10	Dual Specificity Phosphatase 10	Protein Coding	1
131	ADAMTS5	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 5	Protein Coding	1
132	SLC34A2	Solute Carrier Family 34 Member 2	Protein Coding	1
133	CEBPA	CCAAT Enhancer Binding Protein Alpha	Protein Coding	1
134	CDX2	Caudal Type Homeobox 2	Protein Coding	1
135	CDKN2D	Cyclin Dependent Kinase Inhibitor 2D	Protein Coding	1
136	CDKN2C	Cyclin Dependent Kinase Inhibitor 2C	Protein Coding	1
137	CDKN2B	Cyclin Dependent Kinase Inhibitor 2B	Protein Coding	1
138	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	1
139	CDKN1B	Cyclin Dependent Kinase Inhibitor 1B	Protein Coding	1
140	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	1
141	CDK2	Cyclin Dependent Kinase 2	Protein Coding	1
142	RASGRP1	RAS Guanyl Releasing Protein 1	Protein Coding	1
143	BTLA	B And T Lymphocyte Associated	Protein Coding	1
144	DNER	Delta/Notch Like EGF Repeat Containing	Protein Coding	1
145	CCNC	Cyclin C	Protein Coding	1
146	ASAP2	ArfGAP With SH3 Domain, Ankyrin Repeat And PH Domain 2	Protein Coding	1
147	KRT38	Keratin 38	Protein Coding	1
148	KRTAP4-1	Keratin Associated Protein 4-1	Protein Coding	1
149	CRACR2A	Calcium Release Activated Channel Regulator 2A	Protein Coding	1
150	LRRC25	Leucine Rich Repeat Containing 25	Protein Coding	1
151	CASP5	Caspase 5	Protein Coding	1
152	STAM	Signal Transducing Adaptor Molecule	Protein Coding	1
153	ABCA11P	ATP Binding Cassette Subfamily A Member 11, Pseudogene	Pseudogene	1
154	CLMN	Calmin	Protein Coding	1
155	S100G	S100 Calcium Binding Protein G	Protein Coding	1
156	MEG8	Maternally Expressed 8, Small Nucleolar RNA Host Gene	RNA Gene	1
157	SPRR1B	Small Proline Rich Protein 1B	Protein Coding	1
158	IL25	Interleukin 25	Protein Coding	1
159	S100A2	S100 Calcium Binding Protein A2	Protein Coding	1
160	KLK6	Kallikrein Related Peptidase 6	Protein Coding	1
161	TRPV5	Transient Receptor Potential Cation Channel Subfamily V Member 5	Protein Coding	1
162	MED9	Mediator Complex Subunit 9	Protein Coding	1
163	CD200	CD200 Molecule	Protein Coding	1
164	DEFB132	Defensin Beta 132	Protein Coding	1
165	KRT34	Keratin 34	Protein Coding	1
166	KRTAP5-4	Keratin Associated Protein 5-4	Protein Coding	1
167	KRTAP5-1	Keratin Associated Protein 5-1	Protein Coding	1
168	KRTAP10-2	Keratin Associated Protein 10-2	Protein Coding	1
169	KRTAP10-9	Keratin Associated Protein 10-9	Protein Coding	1
170	KRTAP10-7	Keratin Associated Protein 10-7	Protein Coding	1
171	KRTAP10-4	Keratin Associated Protein 10-4	Protein Coding	1
172	DND1	DND MicroRNA-Mediated Repression Inhibitor 1	Protein Coding	1
173	KRTAP12-2	Keratin Associated Protein 12-2	Protein Coding	1
174	LCE1F	Late Cornified Envelope 1F	Protein Coding	1
175	LCE1D	Late Cornified Envelope 1D	Protein Coding	1
176	KRTAP8-1	Keratin Associated Protein 8-1	Protein Coding	1
177	CDC34	Cell Division Cycle 34, Ubiquitin Conjugating Enzyme	Protein Coding	1
178	ATP2C2	ATPase Secretory Pathway Ca2+ Transporting 2	Protein Coding	1
179	CRACR2B	Calcium Release Activated Channel Regulator 2B	Protein Coding	1
180	SOSTDC1	Sclerostin Domain Containing 1	Protein Coding	1
181	IGSF9B	Immunoglobulin Superfamily Member 9B	Protein Coding	1
182	SLC37A2	Solute Carrier Family 37 Member 2	Protein Coding	1
183	CREG2	Cellular Repressor Of E1A Stimulated Genes 2	Protein Coding	1
184	SERPINB1	Serpin Family B Member 1	Protein Coding	1
185	DEFB109C	Defensin Beta 109C (Gene/Pseudogene)	Pseudogene	1

Disorders associated with Vitamin D receptor pathway SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Systemic lupus erythematosus	Enrichment	CTLA4, HLA-DRB1, IRF5, ITGAM, SPP1, TNFAIP3, TNFSF4	6.08
2	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A, CDKN1B, CDKN2B, CDKN2C	5.94
3	Tumoral calcinosis, hyperphosphatemic, familial, 1	Enrichment	FGF23, KL	3.26
4	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL6, MYC	3.26
5	Adult-onset myasthenia gravis	Enrichment	CTLA4, HLA-DQA1	3.26
6	Primary hyperparathyroidism	Enrichment	CDKN1B, PTH	2.96
7	Follicular lymphoma	Enrichment	BCL6, HLA-DRB1	2.74
8	Diffuse cutaneous systemic sclerosis	Enrichment	HLA-DRB1, IRF5	2.74
9	Atrial septal defect 1	Enrichment	TGFB2, TPM1	2.57
10	Limited scleroderma	Enrichment	HLA-DRB1, IRF5	2.57
11	Narcolepsy 1	Enrichment	HLA-DRB1, TNFSF4	2.31
12	Primary biliary cholangitis	Enrichment	IL12A, IRF5	2.20
13	Lymphatic malformation 5	Enrichment	EPHB4	1.87
14	Cardiomyopathy, familial hypertrophic, 3	Enrichment	TPM1	1.87
15	Hepatic adenomas, familial	Enrichment	HNF1A	1.87
16	Endosteal hyperostosis, autosomal dominant	Enrichment	LRP5	1.87
17	High molecular weight kininogen deficiency	Enrichment	KNG1	1.87
18	Pulmonary alveolar microlithiasis	Enrichment	SLC34A2	1.87
19	Pulmonary atresia with intact ventricular septum	Enrichment	TPM1	1.87
20	Bone mineral density quantitative trait locus 1	Enrichment	LRP5	1.87
21	Exudative vitreoretinopathy 4	Enrichment	LRP5	1.87
22	Systemic lupus erythematosus 6	Enrichment	ITGAM	1.87
23	Skin/hair/eye pigmentation, variation in, 8	Enrichment	IRF4	1.87
24	Celiac disease 3	Enrichment	CTLA4	1.87
25	Hemolytic uremic syndrome, atypical 6	Enrichment	THBD	1.87
26	Colchicine resistance	Enrichment	ABCB1	1.87
27	Ivic syndrome	Enrichment	SALL4	1.87
28	Hypoadrenocorticism, familial	Enrichment	ABCD1	1.87
29	Ichthyosis, congenital, autosomal recessive 12	Enrichment	CASP14	1.87
30	Immunodeficiency 32a	Enrichment	IRF8	1.87
31	Immunodeficiency 64 with lymphoproliferation	Enrichment	RASGRP1	1.87
32	Intellectual developmental disorder, autosomal dominant 66	Enrichment	ATP2B1	1.87
33	Developmental delay with dysmorphic facies and dental anomalies	Enrichment	SATB1	1.87
34	Myasthenic syndrome, congenital, 19	Enrichment	COL13A1	1.87
35	Tumoral calcinosis, hyperphosphatemic, familial, 3	Enrichment	KL	1.87
36	Immunodeficiency 131	Enrichment	IRF4	1.87
37	Ectodermal dysplasia 15, hypohidrotic/hair type	Enrichment	CST6	1.87
38	Encephalopathy, acute transient	Enrichment	ABCB1	1.87
39	Hyperhomocysteinemia	Enrichment	CBS	1.87
40	Azoospermia, obstructive, with nephrolithiasis	Enrichment	CLDN2	1.87
41	Angioedema, hereditary, 6	Enrichment	KNG1	1.87
42	Type 1 diabetes mellitus 12	Enrichment	CTLA4	1.87
43	Osteoporosis-pseudoglioma syndrome	Enrichment	LRP5	1.87
44	Pulmonary alveolar proteinosis, acquired	Enrichment	HLA-DRB1	1.87
45	White sponge nevus 2	Enrichment	KRT13	1.87
46	Systemic lupus erythematosus 10	Enrichment	IRF5	1.87
47	Camurati-engelmann disease 2	Enrichment	TGFB2	1.87
48	Inflammatory bowel disease 13	Enrichment	ABCB1	1.87
49	Polycystic liver disease 4 with or without kidney cysts	Enrichment	LRP5	1.87
50	Immunodeficiency with hyper-igm, type 3	Enrichment	CD40	1.87
51	Celiac disease 4	Enrichment	MYO9B	1.87
52	Drug metabolism, poor, cyp2d6-related	Enrichment	CYP2D6	1.87
53	Neuroendocrine tumor	Enrichment	CDKN1B	1.87
54	Agammaglobulinemia 5, autosomal dominant	Enrichment	LRRC8A	1.87
55	Efavirenz, poor metabolism of	Enrichment	CYP2B6	1.87
56	Iron overload	Enrichment	BMP6	1.87
57	Thrombophilia due to thrombomodulin defect	Enrichment	THBD	1.87
58	Hyperparathyroidism	Enrichment	TRPV6	1.87
59	Hypotrichosis 13	Enrichment	KRT71	1.87
60	Brachydactyly, type e2	Enrichment	PTHLH	1.87
61	Encephalitis	Enrichment	ABCD1	1.87
62	Type 1 diabetes mellitus 20	Enrichment	HNF1A	1.87
63	Inflammatory bowel disease 14	Enrichment	IRF5	1.87
64	Tumoral calcinosis, hyperphosphatemic, familial, 2	Enrichment	FGF23	1.87
65	Congenital anomalies of kidney and urinary tract 3	Enrichment	NRIP1	1.87
66	Vitamin d-dependent rickets, type 3	Enrichment	CYP3A4	1.87
67	Developmental and epileptic encephalopathy 68	Enrichment	TRAK1	1.87
68	Hyperparathyroidism, transient neonatal	Enrichment	TRPV6	1.87
69	Den hoed-de boer-voisin syndrome	Enrichment	SATB1	1.87
70	Hypercholesterolemia due to cholesterol 7alpha-hydroxylase deficiency	Enrichment	CYP7A1	1.87
71	X-linked cerebral adrenoleukodystrophy	Enrichment	ABCD1	1.87
72	Cdkn2a cancer predisposition	Enrichment	CDKN2A	1.87
73	Familial behcet-like autoinflammatory syndrome	Enrichment	TNFAIP3	1.87
74	Rickets	Enrichment	VDR	1.87
75	Lrp5-related primary osteoporosis	Enrichment	LRP5	1.87
76	Sirenomelia	Enrichment	CDX2	1.87
77	Syndromic recessive x-linked ichthyosis	Enrichment	STS	1.87
78	Congenital nonspherocytic hemolytic anemia	Enrichment	G6PD	1.87
79	Immunodeficiency 64	Enrichment	RASGRP1	1.87
80	Ebv-induced lymphoproliferative disease due to rasgrp1 deficiency	Enrichment	RASGRP1	1.87
81	Acute myeloid leukemia with mutated cebpa	Enrichment	CEBPA	1.87
82	Atherosclerosis	Enrichment	ALOX5	1.87
83	Whipple disease	Enrichment	IRF4	1.87
84	Anorectal malformation	Enrichment	CDX2	1.87
85	Sall4-related disorders	Enrichment	SALL4	1.87
86	Osteosclerosis-developmental delay-craniosynostosis syndrome	Enrichment	LRP5	1.87
87	Adrenomyeloneuropathy	Enrichment	ABCD1	1.87
88	Alpi-related inflammatory bowel disease	Enrichment	ALPI	1.87
89	Intellectual disability-acpilepsy-dental anomalies-facial dysmorphism syndrome	Enrichment	SATB1	1.87
90	Chronic primary adrenal insufficiency	Enrichment	ABCD1	1.87
91	Ephb4-related lymphatic-related hydrops fetalis	Enrichment	EPHB4	1.87
92	Vein of galen aneurysmal malformation	Enrichment	EPHB4	1.87
93	Multiple sclerosis	Enrichment	CYP27B1, HLA-DRB1	1.82
94	Melanoma, cutaneous malignant 1	Enrichment	CDKN2A, CDKN2B	1.66
95	Lymphatic malformation 1	Enrichment	EPHB4	1.57
96	Hashimoto thyroiditis	Enrichment	CTLA4	1.57
97	Melanoma-astrocytoma syndrome	Enrichment	CDKN2A	1.57
98	Burkitt lymphoma	Enrichment	MYC	1.57
99	Hypoparathyroidism, familial isolated, 1	Enrichment	PTH	1.57
100	Sorsby fundus dystrophy	Enrichment	TIMP3	1.57
101	Camurati-engelmann disease 1	Enrichment	TGFB1	1.57
102	Celiac disease 1	Enrichment	HLA-DQA1	1.57
103	Van buchem disease	Enrichment	LRP5	1.57
104	Immunodeficiency 32b	Enrichment	IRF8	1.57
105	Paget disease of bone 5, juvenile-onset	Enrichment	TNFRSF11B	1.57
106	Hyperparathyroidism, neonatal severe	Enrichment	TRPV6	1.57
107	Intracranial hypertension, idiopathic	Enrichment	EPHB4	1.57
108	Spondyloepimetaphyseal dysplasia, x-linked	Enrichment	ABCD1	1.57
109	Adrenoleukodystrophy	Enrichment	ABCD1	1.57
110	Hyperaldosteronism, familial, type ii	Enrichment	SATB1	1.57
111	3mc syndrome 2	Enrichment	COLEC11	1.57
112	Hypercalcemia, infantile, 1	Enrichment	CYP24A1	1.57
113	Duane-radial ray syndrome	Enrichment	SALL4	1.57
114	Melanoma, cutaneous malignant 2	Enrichment	CDKN2A	1.57
115	Sarcoidosis 1	Enrichment	HLA-DRB1	1.57
116	Autoinflammatory syndrome, familial, behcet-like 1	Enrichment	TNFAIP3	1.57
117	Osteopetrosis, autosomal recessive 2	Enrichment	TNFSF11	1.57
118	Multiple endocrine neoplasia, type iv	Enrichment	CDKN1B	1.57
119	Palmoplantar keratoderma, nonepidermolytic, focal 1	Enrichment	KRT16	1.57
120	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.57
121	Intravascular large b-cell lymphoma	Enrichment	BCL6	1.57
122	Ichthyosis, x-linked	Enrichment	STS	1.57
123	Melanoma-pancreatic cancer syndrome	Enrichment	CDKN2A	1.57
124	Camurati-engelmann disease	Enrichment	TGFB1	1.57
125	Congenital hemolytic anemia	Enrichment	G6PD	1.57
126	Loeys-dietz syndrome 4	Enrichment	TGFB2	1.57
127	Bullous pemphigoid	Enrichment	HLA-DRB1	1.57
128	Hereditary lymphedema i	Enrichment	EPHB4	1.57
129	Glucosephosphate dehydrogenase deficiency	Enrichment	G6PD	1.57
130	White sponge nevus	Enrichment	KRT13	1.57
131	Autosomal recessive infantile hypercalcemia	Enrichment	CYP24A1	1.57
132	Joint contractures, osteochondromas, and b-cell lymphoma	Enrichment	NFATC2	1.57
133	Pediatric multiple sclerosis	Enrichment	HLA-DRB1	1.57
134	Cadds	Enrichment	ABCD1	1.57
135	Hyperinsulinism due to hnf1a deficiency	Enrichment	HNF1A	1.57
136	Primary mediastinal large b-cell lymphoma	Enrichment	BCL6	1.57
137	Osteosclerosis	Enrichment	LRP5	1.57
138	Precursor t-cell acute lymphoblastic leukemia	Enrichment	CDKN2A, MYC	1.41
139	Palmoplantar keratoderma, epidermolytic, 1	Enrichment	KRT16	1.39
140	Brachydactyly, type e1	Enrichment	PTHLH	1.39
141	Hypophosphatemic rickets, autosomal dominant	Enrichment	FGF23	1.39
142	Homocystinuria due to cystathionine beta-synthase deficiency	Enrichment	CBS	1.39
143	Mycosis fungoides	Enrichment	CTLA4	1.39
144	Vitamin d hydroxylation-deficient rickets, type 1a	Enrichment	CYP27B1	1.39
145	Osteopetrosis, autosomal dominant 1	Enrichment	LRP5	1.39
146	Coumarin resistance	Enrichment	CYP2C9	1.39
147	Ehlers-danlos syndrome, kyphoscoliotic type, 1	Enrichment	ABCD1	1.39
148	Immune dysregulation with autoimmunity, immunodeficiency, and lymphoproliferation	Enrichment	CTLA4	1.39
149	Keratoderma-ichthyosis-deafness syndrome, autosomal recessive	Enrichment	HNF1A	1.39
150	Familial isolated hypoparathyroidism	Enrichment	PTH	1.39
151	Asparagine synthetase deficiency	Enrichment	CTLA4	1.39
152	Lymphatic malformation 7	Enrichment	EPHB4	1.39
153	Capillary malformation-arteriovenous malformation 2	Enrichment	EPHB4	1.39
154	Chromophobe renal cell carcinoma	Enrichment	HNF1A	1.39
155	Duane retraction syndrome	Enrichment	SALL4	1.39
156	Intellectual developmental disorder, autosomal dominant 30, with speech delay and behavioral abnormalities	Enrichment	ATP2B1	1.39
157	Plod1-related kyphoscoliotic ehlers-danlos syndrome	Enrichment	ABCD1	1.39
158	Congenital microcephaly - severe encephalopathy - progressive cerebral atrophy syndrome	Enrichment	CTLA4	1.39
159	Homocystinuria	Enrichment	CBS	1.39
160	Enchondromatosis	Enrichment	HIF1A	1.39
161	Vogt-koyanagi-harada disease	Enrichment	HLA-DRB1	1.39
162	Saczary syndrome	Enrichment	CTLA4	1.39
163	Myeloma, multiple	Enrichment	CCND1, CDKN2C, RXRA	1.39
164	Tetralogy of fallot	Enrichment	EPHB4, TPM1	1.31
165	Pachyonychia congenita 1	Enrichment	KRT16	1.27
166	Temporal arteritis	Enrichment	HLA-DRB1	1.27
167	Maturity-onset diabetes of the young, type 3	Enrichment	HNF1A	1.27
168	Immunodeficiency, common variable, 1	Enrichment	CTLA4	1.27
169	Chondrocalcinosis 2	Enrichment	TNFRSF11B	1.27
170	Bone mineral density quantitative trait locus 15	Enrichment	TRPV6	1.27
171	Mantle cell lymphoma	Enrichment	CCND1	1.27
172	Retinopathy of prematurity	Enrichment	LRP5	1.27
173	Idiopathic achalasia	Enrichment	HLA-DQA1	1.27
174	Autosomal recessive osteopetrosis	Enrichment	TNFSF11	1.27
175	Pediatric systemic lupus erythematosus	Enrichment	SPP1	1.27
176	Systemic-onset juvenile idiopathic arthritis	Enrichment	HLA-DRB1	1.27
177	Vitreoretinopathy	Enrichment	LRP5	1.27
178	Clear cell papillary renal cell carcinoma	Enrichment	HNF1A	1.27
179	Hereditary angioedema with normal c1inh not related to f12 or plg variant	Enrichment	KNG1	1.27
180	Bladder cancer	Enrichment	CDKN1A, CDKN2A	1.23
181	Enchondromatosis, multiple, ollier type	Enrichment	HIF1A	1.18
182	Exudative vitreoretinopathy 1	Enrichment	LRP5	1.18
183	Von hippel-lindau syndrome	Enrichment	CCND1	1.18
184	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	G6PD	1.18
185	Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-negative	Enrichment	SALL4	1.18
186	Vitamin d-dependent rickets, type 2a	Enrichment	VDR	1.18
187	Rhabdomyosarcoma 2	Enrichment	FOXO1	1.18
188	Narcolepsy 2	Enrichment	HLA-DRB1	1.18
189	Familial woolly hair syndrome	Enrichment	KRT71	1.18
190	Inherited acute myeloid leukemia	Enrichment	CEBPA	1.18
191	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	CEBPA	1.18
192	Li-fraumeni syndrome	Enrichment	CDKN2A	1.10
193	Pierre robin syndrome	Enrichment	ATP2B1	1.10
194	Type 1 diabetes mellitus	Enrichment	HNF1A	1.10
195	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	1.10
196	Granulomatosis with polyangiitis	Enrichment	CTLA4	1.10
197	3mc syndrome	Enrichment	COLEC11	1.10
198	Adrenocortical carcinoma	Enrichment	CDKN2A	1.10
199	Clear cell renal cell carcinoma	Enrichment	HNF1A	1.10
200	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	1.10
201	Lung squamous cell carcinoma	Enrichment	CDKN2A	1.10
202	Atypical hemolytic uremic syndrome with complement gene abnormality	Enrichment	THBD	1.10
203	Capillary malformation-arteriovenous malformation 1	Enrichment	EPHB4	1.04
204	Multiple enchondromatosis, maffucci type	Enrichment	HIF1A	1.04
205	Megacolon	Enrichment	SLC8A1	1.04
206	Hypophosphatemic rickets	Enrichment	FGF23	1.04
207	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	CDKN2A	1.04
208	Hemochromatosis, type 1	Enrichment	BMP6	0.98
209	Exudative vitreoretinopathy	Enrichment	LRP5	0.98
210	Myocarditis	Enrichment	ABCD1	0.98
211	Type 2 diabetes mellitus	Enrichment	HNF1A, SLC2A4	0.95
212	Rheumatoid arthritis	Enrichment	IRF5	0.93
213	Inflammatory bowel disease 1	Enrichment	PRKCQ	0.93
214	Coronary heart disease 5	Enrichment	G6PD	0.93
215	Loeys-dietz syndrome	Enrichment	TGFB2	0.93
216	Arteriovenous malformation	Enrichment	EPHB4	0.93
217	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	CBS, TGFB2	0.92
218	Marfan syndrome	Enrichment	TGFB2	0.89
219	Leukemia, chronic lymphocytic	Enrichment	CCND1	0.89
220	Myopathy, x-linked, with excessive autophagy	Enrichment	EPHB4	0.89
221	Melanoma	Enrichment	CDKN2A	0.89
222	Autosomal non-syndromic agammaglobulinemia	Enrichment	LRRC8A	0.89
223	Asthma	Enrichment	ALOX5	0.85
224	Epilepsy, idiopathic generalized	Enrichment	ABCB1	0.85
225	Leukemia, acute lymphoblastic	Enrichment	CDKN2A	0.85
226	Diabetes mellitus	Enrichment	HNF1A	0.85
227	Presynaptic congenital myasthenic syndromes	Enrichment	COL13A1	0.85
228	Digeorge syndrome	Enrichment	HNF1A	0.82
229	Lip and oral cavity carcinoma	Enrichment	CDKN2A	0.82
230	Postsynaptic congenital myasthenic syndromes	Enrichment	COL13A1	0.82
231	Ovarian cancer	Enrichment	CDKN1B, CDKN2A, HNF1A	0.80
232	Clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly	Enrichment	ATP2B1	0.79
233	Pulmonary disease, chronic obstructive	Enrichment	VDR	0.79
234	Clubfoot	Enrichment	ATP2B1	0.79
235	Osteoporosis	Enrichment	LRP5	0.76
236	Periventricular nodular heterotopia	Enrichment	ATP2B1	0.76
237	Renal cell carcinoma, nonpapillary	Enrichment	HNF1A	0.73
238	Hypertension, essential	Enrichment	CYP3A5	0.68
239	Pancreatitis, hereditary	Enrichment	TRPV6	0.68
240	Cardiomyopathy, dilated, 1e	Enrichment	TPM1	0.68
241	Polycystic liver disease	Enrichment	LRP5	0.68
242	Autosomal dominant polycystic liver disease	Enrichment	LRP5	0.68
243	Arteriovenous malformations of the brain	Enrichment	TIMP3	0.64
244	Behcet syndrome	Enrichment	IL12A	0.64
245	Diffuse large b-cell lymphoma	Enrichment	FOXO1	0.64
246	Esophageal atresia/tracheoesophageal fistula	Enrichment	IRF8	0.64
247	Ehlers-danlos syndrome	Enrichment	TGFB2	0.64
248	Maturity-onset diabetes of the young	Enrichment	HNF1A	0.62
249	Cardiomyopathy, dilated, 1a	Enrichment	NFATC2	0.60
250	Hepatocellular carcinoma	Enrichment	VDR	0.58
251	Myocardial infarction	Enrichment	TNFSF4	0.58
252	Inherited cancer-predisposing syndrome	Enrichment	CDKN1B, CDKN2A, CEBPA	0.57
253	Brittle bone disorder	Enrichment	LRP5	0.57
254	Malaria	Enrichment	G6PD	0.57
255	Breast cancer	Enrichment	CDKN2B, HNF1A	0.56
256	Cardiomyopathy, familial hypertrophic, 1	Enrichment	TPM1	0.55
257	Pancreatic cancer	Enrichment	CDKN2A	0.54
258	Hydrops fetalis, nonimmune	Enrichment	EPHB4	0.52
259	Hirschsprung disease 1	Enrichment	ABCD1	0.48
260	Non-immune hydrops fetalis	Enrichment	EPHB4	0.46
261	Cystic fibrosis	Enrichment	TGFB1	0.45
262	Connective tissue disease	Enrichment	CBS	0.45
263	Familial hypertrophic cardiomyopathy	Enrichment	TPM1	0.44
264	Male infertility	Enrichment	CLDN2	0.43
265	Cakut	Enrichment	NRIP1	0.43
266	Left ventricular noncompaction	Enrichment	TPM1	0.42
267	Leukemia, acute myeloid	Enrichment	CEBPA	0.37
268	Gastric cancer	Enrichment	CDKN2A	0.35
269	Hypertrophic cardiomyopathy	Enrichment	TPM1	0.35
270	Thrombocytopenia	Enrichment	THBD	0.32
271	Body mass index quantitative trait locus 11	Enrichment	CDKAL1	0.30
272	Familial isolated dilated cardiomyopathy	Enrichment	TPM1	0.29
273	Hereditary breast ovarian cancer syndrome	Enrichment	SLC34A2	0.28
274	Undetermined early-onset epileptic encephalopathy	Enrichment	TRAK1	0.27
275	Primary ovarian insufficiency	Enrichment	BMP6	0.25
276	Autism	Enrichment	ATP2B1	0.20
277	Dilated cardiomyopathy	Enrichment	TPM1	0.18
278	Colorectal cancer	Enrichment	CCND1	0.16
279	Congenital nervous system abnormality	Enrichment	ABCD1	0.11
280	Nervous system disease	Enrichment	ABCD1	0.11
281	Complex neurodevelopmental disorder	Enrichment	ATP2B1	0.09
282	Hereditary retinal dystrophy	Enrichment	LRP5, TIMP3	0.04
283	Fundus dystrophy	Enrichment	LRP5, TIMP3	0.04

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Vitamin D receptor pathway

Pathway Network for Vitamin D receptor pathway

Member Pathways for Vitamin D receptor pathway

Pathways in the Vitamin D receptor pathway SuperPath

Associated Genes for Vitamin D receptor pathway

Associated Disorders for Vitamin D receptor pathway

Disorders associated with Vitamin D receptor pathway SuperPath

STRING Interaction Network for Vitamin D receptor pathway

Sources for Vitamin D receptor pathway