Wax and plasmalogen biosynthesis

Sources:

#	Name	Source	Genes
1	Wax and plasmalogen biosynthesis	Reactome	AGPS AWAT1 AWAT2 DHRS7B FAR1 FAR2 GNPAT (see all 7) (see less)
2	Wax biosynthesis	Reactome	AWAT1 AWAT2 FAR1 FAR2
3	Plasmalogen biosynthesis	Reactome	AGPS DHRS7B GNPAT

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	AWAT1	Acyl-CoA Wax Alcohol Acyltransferase 1	Protein Coding	2
2	AWAT2	Acyl-CoA Wax Alcohol Acyltransferase 2	Protein Coding	2
3	DHRS7B	Dehydrogenase/Reductase 7B	Protein Coding	2
4	FAR2	Fatty Acyl-CoA Reductase 2	Protein Coding	2
5	FAR1	Fatty Acyl-CoA Reductase 1	Protein Coding	2
6	GNPAT	Glyceronephosphate O-Acyltransferase	Protein Coding	2
7	AGPS	Alkylglycerone Phosphate Synthase	Protein Coding	2

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Rhizomelic chondrodysplasia punctata	Enrichment	AGPS, GNPAT	6.71
2	Rhizomelic chondrodysplasia punctata, type 2	Enrichment	GNPAT	3.66
3	Rhizomelic chondrodysplasia punctata, type 3	Enrichment	AGPS	3.66
4	Peroxisomal fatty acyl-coa reductase 1 disorder	Enrichment	FAR1	3.53
5	Cataracts, spastic paraparesis, and speech delay	Enrichment	FAR1	3.53
6	Fatty acyl-coa reductase 1 deficiency	Enrichment	FAR1	3.53

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Wax and plasmalogen biosynthesis